{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1663
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 1029
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 929
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 888
    },
    {
      "term": "NEUTROPENIA",
      "count": 846
    },
    {
      "term": "ANAEMIA",
      "count": 824
    },
    {
      "term": "PYREXIA",
      "count": 795
    },
    {
      "term": "NAUSEA",
      "count": 758
    },
    {
      "term": "VOMITING",
      "count": 615
    },
    {
      "term": "DIARRHOEA",
      "count": 580
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 524
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 507
    },
    {
      "term": "FATIGUE",
      "count": 499
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 499
    },
    {
      "term": "ASTHENIA",
      "count": 497
    },
    {
      "term": "DEATH",
      "count": 492
    },
    {
      "term": "DYSPNOEA",
      "count": 476
    },
    {
      "term": "PNEUMONIA",
      "count": 465
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 431
    },
    {
      "term": "SEPSIS",
      "count": 423
    },
    {
      "term": "PANCYTOPENIA",
      "count": 421
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 403
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 367
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 367
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 366
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 350
    },
    {
      "term": "DECREASED APPETITE",
      "count": 348
    },
    {
      "term": "LEUKOPENIA",
      "count": 334
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 317
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 298
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 295
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 275
    },
    {
      "term": "DEHYDRATION",
      "count": 264
    },
    {
      "term": "RASH",
      "count": 252
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 251
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 246
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 236
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 212
    },
    {
      "term": "CONSTIPATION",
      "count": 211
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 211
    },
    {
      "term": "CHOLANGITIS",
      "count": 208
    },
    {
      "term": "HYPOTENSION",
      "count": 200
    },
    {
      "term": "PAIN",
      "count": 199
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 188
    },
    {
      "term": "MALAISE",
      "count": 185
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 183
    },
    {
      "term": "INFECTION",
      "count": 172
    },
    {
      "term": "ASCITES",
      "count": 169
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 169
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 169
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 169
    },
    {
      "term": "DIZZINESS",
      "count": 168
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 164
    },
    {
      "term": "RENAL FAILURE",
      "count": 161
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 157
    },
    {
      "term": "ERYTHEMA",
      "count": 157
    },
    {
      "term": "HYPERTENSION",
      "count": 154
    },
    {
      "term": "CHILLS",
      "count": 151
    },
    {
      "term": "PNEUMONITIS",
      "count": 150
    },
    {
      "term": "PRURITUS",
      "count": 147
    },
    {
      "term": "COUGH",
      "count": 146
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 145
    },
    {
      "term": "CHEST PAIN",
      "count": 145
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 144
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 141
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 139
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 138
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 129
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 128
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 121
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 120
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 120
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 119
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 117
    },
    {
      "term": "HEADACHE",
      "count": 116
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 115
    },
    {
      "term": "NEUROTOXICITY",
      "count": 115
    },
    {
      "term": "FALL",
      "count": 114
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 113
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 112
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 112
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 110
    },
    {
      "term": "CYTOPENIA",
      "count": 107
    },
    {
      "term": "TACHYCARDIA",
      "count": 106
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 105
    },
    {
      "term": "EPISTAXIS",
      "count": 104
    },
    {
      "term": "PARAESTHESIA",
      "count": 104
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 97
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 93
    },
    {
      "term": "OEDEMA",
      "count": 93
    },
    {
      "term": "BACTERAEMIA",
      "count": 92
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 92
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 92
    },
    {
      "term": "COLITIS",
      "count": 91
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 91
    },
    {
      "term": "HYPOXIA",
      "count": 90
    },
    {
      "term": "ALOPECIA",
      "count": 88
    },
    {
      "term": "MYOSITIS",
      "count": 86
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 85
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 84
    }
  ]
}