{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 149
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 120
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 80
    },
    {
      "term": "NEUTROPENIA",
      "count": 74
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 61
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 57
    },
    {
      "term": "PANCYTOPENIA",
      "count": 36
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 35
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 34
    },
    {
      "term": "LEUKOPENIA",
      "count": 29
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 29
    },
    {
      "term": "DEATH",
      "count": 28
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 27
    },
    {
      "term": "DIARRHOEA",
      "count": 25
    },
    {
      "term": "PYREXIA",
      "count": 25
    },
    {
      "term": "RENAL FAILURE",
      "count": 25
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 25
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 23
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 21
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 20
    },
    {
      "term": "ASPERGILLOSIS",
      "count": 19
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 19
    },
    {
      "term": "PNEUMONIA",
      "count": 19
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 18
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 18
    },
    {
      "term": "CYTOMEGALOVIRUS CHORIORETINITIS",
      "count": 17
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 17
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 17
    },
    {
      "term": "SEPSIS",
      "count": 17
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 17
    },
    {
      "term": "CYTOMEGALOVIRUS COLITIS",
      "count": 15
    },
    {
      "term": "STENOTROPHOMONAS INFECTION",
      "count": 15
    },
    {
      "term": "ANAEMIA",
      "count": 14
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 14
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 14
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 14
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 13
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 13
    },
    {
      "term": "CONVULSION",
      "count": 12
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 12
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 12
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 12
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 12
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 12
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 12
    },
    {
      "term": "PNEUMONIA CYTOMEGALOVIRAL",
      "count": 12
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 12
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 12
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 12
    },
    {
      "term": "VOMITING",
      "count": 12
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 11
    },
    {
      "term": "BRAIN ABSCESS",
      "count": 11
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 11
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 11
    },
    {
      "term": "POST PROCEDURAL COMPLICATION",
      "count": 11
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 11
    },
    {
      "term": "DEHYDRATION",
      "count": 10
    },
    {
      "term": "NAUSEA",
      "count": 10
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 10
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 10
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 9
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 9
    },
    {
      "term": "BLOOD PRESSURE FLUCTUATION",
      "count": 9
    },
    {
      "term": "CHOLESTASIS",
      "count": 9
    },
    {
      "term": "FUSARIUM INFECTION",
      "count": 9
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 9
    },
    {
      "term": "HYPOTENSION",
      "count": 9
    },
    {
      "term": "INFECTION",
      "count": 9
    },
    {
      "term": "INTRACRANIAL INFECTION",
      "count": 9
    },
    {
      "term": "RASH",
      "count": 9
    },
    {
      "term": "SHOCK",
      "count": 9
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 9
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 8
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 8
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 8
    },
    {
      "term": "CYTOMEGALOVIRUS TEST POSITIVE",
      "count": 8
    },
    {
      "term": "DECREASED APPETITE",
      "count": 8
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 8
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 8
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 8
    },
    {
      "term": "LUNG DISORDER",
      "count": 8
    },
    {
      "term": "RETINAL TOXICITY",
      "count": 8
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 8
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 7
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 7
    },
    {
      "term": "ASTHENIA",
      "count": 7
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 7
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 7
    },
    {
      "term": "EPILEPSY",
      "count": 7
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION",
      "count": 7
    },
    {
      "term": "IMPRISONMENT",
      "count": 7
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 7
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 7
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 6
    },
    {
      "term": "BLINDNESS",
      "count": 6
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 6
    },
    {
      "term": "CARDIAC ARREST",
      "count": 6
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 6
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 6
    },
    {
      "term": "COUGH",
      "count": 6
    }
  ]
}