{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 2706
    },
    {
      "term": "FATIGUE",
      "count": 1762
    },
    {
      "term": "NEUTROPENIA",
      "count": 1640
    },
    {
      "term": "NAUSEA",
      "count": 1501
    },
    {
      "term": "METASTASES TO BONE",
      "count": 1418
    },
    {
      "term": "DEATH",
      "count": 1369
    },
    {
      "term": "DIARRHOEA",
      "count": 1319
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 1187
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 1152
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 991
    },
    {
      "term": "ASTHENIA",
      "count": 908
    },
    {
      "term": "VOMITING",
      "count": 866
    },
    {
      "term": "PAIN",
      "count": 845
    },
    {
      "term": "DYSPNOEA",
      "count": 836
    },
    {
      "term": "ANAEMIA",
      "count": 799
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 781
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 771
    },
    {
      "term": "OFF LABEL USE",
      "count": 745
    },
    {
      "term": "DECREASED APPETITE",
      "count": 721
    },
    {
      "term": "RASH",
      "count": 671
    },
    {
      "term": "ARTHRALGIA",
      "count": 667
    },
    {
      "term": "MALAISE",
      "count": 665
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 641
    },
    {
      "term": "BREAST CANCER",
      "count": 640
    },
    {
      "term": "PYREXIA",
      "count": 572
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 572
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 564
    },
    {
      "term": "COUGH",
      "count": 561
    },
    {
      "term": "ALOPECIA",
      "count": 555
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 542
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 529
    },
    {
      "term": "DIZZINESS",
      "count": 520
    },
    {
      "term": "HEADACHE",
      "count": 512
    },
    {
      "term": "LEUKOPENIA",
      "count": 495
    },
    {
      "term": "PRURITUS",
      "count": 456
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 455
    },
    {
      "term": "BACK PAIN",
      "count": 450
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 440
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 438
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 434
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 431
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 422
    },
    {
      "term": "CONSTIPATION",
      "count": 388
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 347
    },
    {
      "term": "DECREASED IMMUNE RESPONSIVENESS",
      "count": 342
    },
    {
      "term": "PNEUMONIA",
      "count": 327
    },
    {
      "term": "COVID-19",
      "count": 323
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 322
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 310
    },
    {
      "term": "TUMOUR MARKER INCREASED",
      "count": 305
    },
    {
      "term": "BONE PAIN",
      "count": 291
    },
    {
      "term": "HYPERTENSION",
      "count": 288
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 286
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 276
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 274
    },
    {
      "term": "DRY SKIN",
      "count": 274
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 273
    },
    {
      "term": "ASCITES",
      "count": 271
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 259
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 258
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 256
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 255
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 251
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 241
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 241
    },
    {
      "term": "FALL",
      "count": 240
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 237
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 236
    },
    {
      "term": "STOMATITIS",
      "count": 233
    },
    {
      "term": "METASTASIS",
      "count": 229
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 223
    },
    {
      "term": "ERYTHEMA",
      "count": 209
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 209
    },
    {
      "term": "INSOMNIA",
      "count": 208
    },
    {
      "term": "DEHYDRATION",
      "count": 206
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 204
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 202
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 199
    },
    {
      "term": "ANXIETY",
      "count": 197
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 195
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 191
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 189
    },
    {
      "term": "CARBOHYDRATE ANTIGEN 15-3 INCREASED",
      "count": 188
    },
    {
      "term": "CHEST PAIN",
      "count": 186
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 186
    },
    {
      "term": "ILLNESS",
      "count": 184
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 184
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 180
    },
    {
      "term": "PNEUMONITIS",
      "count": 180
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 178
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 178
    },
    {
      "term": "HOT FLUSH",
      "count": 176
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 174
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 172
    },
    {
      "term": "INFECTION",
      "count": 172
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 171
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 167
    },
    {
      "term": "METASTASES TO SPINE",
      "count": 166
    },
    {
      "term": "CHILLS",
      "count": 165
    },
    {
      "term": "SOMNOLENCE",
      "count": 164
    }
  ]
}