{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 297
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 151
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 145
    },
    {
      "term": "PANCYTOPENIA",
      "count": 116
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 102
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 98
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 92
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 80
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 80
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 79
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 77
    },
    {
      "term": "ENCEPHALITIS CYTOMEGALOVIRUS",
      "count": 77
    },
    {
      "term": "PYREXIA",
      "count": 64
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 63
    },
    {
      "term": "GENERALISED OEDEMA",
      "count": 61
    },
    {
      "term": "LUNG DISORDER",
      "count": 60
    },
    {
      "term": "EPSTEIN-BARR VIRAEMIA",
      "count": 56
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 56
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 51
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 46
    },
    {
      "term": "APLASTIC ANAEMIA",
      "count": 45
    },
    {
      "term": "DIARRHOEA",
      "count": 41
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 41
    },
    {
      "term": "RENAL FAILURE",
      "count": 37
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 36
    },
    {
      "term": "CYTOMEGALOVIRUS CHORIORETINITIS",
      "count": 35
    },
    {
      "term": "PNEUMONIA",
      "count": 35
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 32
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 31
    },
    {
      "term": "SEPSIS",
      "count": 31
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 30
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 28
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 27
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 27
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 26
    },
    {
      "term": "NAUSEA",
      "count": 23
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 22
    },
    {
      "term": "HERPES SIMPLEX",
      "count": 21
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 21
    },
    {
      "term": "NEUTROPENIA",
      "count": 21
    },
    {
      "term": "PNEUMONIA CYTOMEGALOVIRAL",
      "count": 21
    },
    {
      "term": "VOMITING",
      "count": 21
    },
    {
      "term": "CHRONIC GRAFT VERSUS HOST DISEASE",
      "count": 20
    },
    {
      "term": "CYTOMEGALOVIRUS TEST POSITIVE",
      "count": 20
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 20
    },
    {
      "term": "HUMAN HERPESVIRUS 6 INFECTION",
      "count": 20
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 20
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 20
    },
    {
      "term": "INFECTION",
      "count": 19
    },
    {
      "term": "HAEMATURIA",
      "count": 18
    },
    {
      "term": "RETINITIS VIRAL",
      "count": 18
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 18
    },
    {
      "term": "VIRAL HAEMORRHAGIC CYSTITIS",
      "count": 18
    },
    {
      "term": "ANAEMIA",
      "count": 17
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 17
    },
    {
      "term": "LEUKOPENIA",
      "count": 16
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 16
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 15
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 15
    },
    {
      "term": "DEATH",
      "count": 15
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 15
    },
    {
      "term": "RENAL TUBULAR DISORDER",
      "count": 15
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 14
    },
    {
      "term": "DYSPNOEA",
      "count": 14
    },
    {
      "term": "RENAL TUBULAR INJURY",
      "count": 14
    },
    {
      "term": "ACIDOSIS HYPERCHLORAEMIC",
      "count": 13
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 13
    },
    {
      "term": "HYPOMAGNESAEMIA",
      "count": 13
    },
    {
      "term": "HYPOURICAEMIA",
      "count": 13
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 13
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 12
    },
    {
      "term": "GLYCOSURIA",
      "count": 12
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 12
    },
    {
      "term": "CYTOMEGALOVIRUS GASTRITIS",
      "count": 11
    },
    {
      "term": "HYPERTENSION",
      "count": 11
    },
    {
      "term": "PARAESTHESIA",
      "count": 11
    },
    {
      "term": "VARICELLA ZOSTER VIRUS INFECTION",
      "count": 11
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 11
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 10
    },
    {
      "term": "COLITIS",
      "count": 10
    },
    {
      "term": "CYTOMEGALOVIRUS ENTEROCOLITIS",
      "count": 10
    },
    {
      "term": "DRUG INTERACTION",
      "count": 10
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 10
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 10
    },
    {
      "term": "LEUKAEMIA",
      "count": 10
    },
    {
      "term": "PAIN",
      "count": 10
    },
    {
      "term": "SEIZURE",
      "count": 10
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 10
    },
    {
      "term": "CYTOMEGALOVIRUS OESOPHAGITIS",
      "count": 9
    },
    {
      "term": "HYPOTENSION",
      "count": 9
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 9
    },
    {
      "term": "LYMPHOPENIA",
      "count": 9
    },
    {
      "term": "OESOPHAGEAL CANDIDIASIS",
      "count": 9
    },
    {
      "term": "ORGAN FAILURE",
      "count": 9
    },
    {
      "term": "STOMATITIS",
      "count": 9
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 9
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 9
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE",
      "count": 8
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 8
    },
    {
      "term": "ASCITES",
      "count": 8
    }
  ]
}