{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 66
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 50
    },
    {
      "term": "OVERDOSE",
      "count": 37
    },
    {
      "term": "OFF LABEL USE",
      "count": 32
    },
    {
      "term": "METABOLIC ACIDOSIS",
      "count": 25
    },
    {
      "term": "HYPOTENSION",
      "count": 19
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 18
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 17
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 17
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 16
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 16
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 13
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 12
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 11
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 11
    },
    {
      "term": "ACUTE HEPATIC FAILURE",
      "count": 10
    },
    {
      "term": "COAGULOPATHY",
      "count": 10
    },
    {
      "term": "TACHYCARDIA",
      "count": 9
    },
    {
      "term": "COMA",
      "count": 8
    },
    {
      "term": "LIVER INJURY",
      "count": 8
    },
    {
      "term": "ACIDOSIS",
      "count": 7
    },
    {
      "term": "BRAIN HERNIATION",
      "count": 7
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 7
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 7
    },
    {
      "term": "ALCOHOL POISONING",
      "count": 6
    },
    {
      "term": "ANION GAP",
      "count": 6
    },
    {
      "term": "HAEMODIALYSIS",
      "count": 6
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 6
    },
    {
      "term": "TACHYPNOEA",
      "count": 6
    },
    {
      "term": "BRAIN DEATH",
      "count": 5
    },
    {
      "term": "DRUG ABUSE",
      "count": 5
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 5
    },
    {
      "term": "HYPOTHERMIA",
      "count": 5
    },
    {
      "term": "PANCREATITIS",
      "count": 5
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 5
    },
    {
      "term": "SHOCK",
      "count": 5
    },
    {
      "term": "ANALGESIC DRUG LEVEL INCREASED",
      "count": 4
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 4
    },
    {
      "term": "BLOOD OSMOLARITY INCREASED",
      "count": 4
    },
    {
      "term": "CARDIAC ARREST",
      "count": 4
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 4
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 3
    },
    {
      "term": "ANION GAP INCREASED",
      "count": 3
    },
    {
      "term": "BRADYCARDIA",
      "count": 3
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 3
    },
    {
      "term": "CYANOSIS",
      "count": 3
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 3
    },
    {
      "term": "DRUG ADMINISTRATION ERROR",
      "count": 3
    },
    {
      "term": "DRUG INTERACTION",
      "count": 3
    },
    {
      "term": "DRUG TOXICITY",
      "count": 3
    },
    {
      "term": "ELECTROCARDIOGRAM QRS COMPLEX PROLONGED",
      "count": 3
    },
    {
      "term": "HAEMORRHAGE",
      "count": 3
    },
    {
      "term": "HYPERTENSION",
      "count": 3
    },
    {
      "term": "LEUKOCYTOSIS",
      "count": 3
    },
    {
      "term": "OSMOLAR GAP INCREASED",
      "count": 3
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 3
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 3
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 3
    },
    {
      "term": "SINUS TACHYCARDIA",
      "count": 3
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 2
    },
    {
      "term": "ASTHENIA",
      "count": 2
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 2
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 2
    },
    {
      "term": "BLOOD LACTIC ACID INCREASED",
      "count": 2
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 2
    },
    {
      "term": "BRAIN INJURY",
      "count": 2
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 2
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 2
    },
    {
      "term": "DEATH",
      "count": 2
    },
    {
      "term": "DELIRIUM",
      "count": 2
    },
    {
      "term": "DIALYSIS",
      "count": 2
    },
    {
      "term": "DIFFUSE AXONAL INJURY",
      "count": 2
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 2
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 2
    },
    {
      "term": "FATIGUE",
      "count": 2
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 2
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 2
    },
    {
      "term": "HYPERAMMONAEMIA",
      "count": 2
    },
    {
      "term": "HYPERKALIURIA",
      "count": 2
    },
    {
      "term": "HYPOPHAGIA",
      "count": 2
    },
    {
      "term": "INTESTINAL ISCHAEMIA",
      "count": 2
    },
    {
      "term": "INTRACRANIAL PRESSURE INCREASED",
      "count": 2
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 2
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 2
    },
    {
      "term": "NAUSEA",
      "count": 2
    },
    {
      "term": "OSMOLAR GAP",
      "count": 2
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 2
    },
    {
      "term": "PRODUCT PRESCRIBING ISSUE",
      "count": 2
    },
    {
      "term": "PYREXIA",
      "count": 2
    },
    {
      "term": "PYROGLUTAMIC ACIDOSIS",
      "count": 2
    },
    {
      "term": "REBOUND EFFECT",
      "count": 2
    },
    {
      "term": "RENAL CELL CARCINOMA",
      "count": 2
    },
    {
      "term": "RENAL FAILURE",
      "count": 2
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 2
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 2
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 2
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 2
    },
    {
      "term": "SOMNOLENCE",
      "count": 2
    },
    {
      "term": "STARVATION KETOACIDOSIS",
      "count": 2
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 2
    }
  ]
}