{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1396
    },
    {
      "term": "PYREXIA",
      "count": 952
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 834
    },
    {
      "term": "NEUTROPENIA",
      "count": 597
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 529
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 528
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 493
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 490
    },
    {
      "term": "SEPSIS",
      "count": 451
    },
    {
      "term": "PANCYTOPENIA",
      "count": 428
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 417
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 414
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 414
    },
    {
      "term": "PNEUMONIA",
      "count": 404
    },
    {
      "term": "DIARRHOEA",
      "count": 384
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 382
    },
    {
      "term": "INFECTION",
      "count": 374
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 326
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 323
    },
    {
      "term": "NAUSEA",
      "count": 317
    },
    {
      "term": "ANAEMIA",
      "count": 305
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 300
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 298
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 296
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 286
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 278
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 271
    },
    {
      "term": "DEATH",
      "count": 257
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 257
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 252
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 246
    },
    {
      "term": "CHRONIC GRAFT VERSUS HOST DISEASE",
      "count": 243
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 243
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 226
    },
    {
      "term": "ADENOVIRUS INFECTION",
      "count": 225
    },
    {
      "term": "RENAL FAILURE",
      "count": 216
    },
    {
      "term": "HYPOTENSION",
      "count": 203
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 203
    },
    {
      "term": "VOMITING",
      "count": 202
    },
    {
      "term": "DYSPNOEA",
      "count": 199
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 193
    },
    {
      "term": "PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY",
      "count": 193
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION",
      "count": 191
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 190
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 181
    },
    {
      "term": "HYPERTENSION",
      "count": 175
    },
    {
      "term": "RASH",
      "count": 175
    },
    {
      "term": "STOMATITIS",
      "count": 174
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 173
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 169
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 168
    },
    {
      "term": "FATIGUE",
      "count": 167
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 164
    },
    {
      "term": "HYPOGAMMAGLOBULINAEMIA",
      "count": 164
    },
    {
      "term": "MALAISE",
      "count": 162
    },
    {
      "term": "IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME",
      "count": 154
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 153
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 151
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 150
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 149
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 149
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 147
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 145
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN INTESTINE",
      "count": 142
    },
    {
      "term": "ASTHENIA",
      "count": 142
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 139
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 138
    },
    {
      "term": "HERPES ZOSTER",
      "count": 137
    },
    {
      "term": "HEADACHE",
      "count": 136
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 136
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 133
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 132
    },
    {
      "term": "CYTOPENIA",
      "count": 130
    },
    {
      "term": "POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME",
      "count": 128
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 127
    },
    {
      "term": "NEUROTOXICITY",
      "count": 127
    },
    {
      "term": "BACTERAEMIA",
      "count": 124
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 122
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 120
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 120
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 117
    },
    {
      "term": "STEM CELL TRANSPLANT",
      "count": 116
    },
    {
      "term": "HERPES SIMPLEX",
      "count": 115
    },
    {
      "term": "HYPOXIA",
      "count": 114
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 113
    },
    {
      "term": "COUGH",
      "count": 113
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 113
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 112
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 112
    },
    {
      "term": "STAPHYLOCOCCAL SEPSIS",
      "count": 111
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 110
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 109
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 107
    },
    {
      "term": "VENOOCCLUSIVE DISEASE",
      "count": 107
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 106
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 103
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 102
    },
    {
      "term": "ASCITES",
      "count": 101
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 100
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 98
    }
  ]
}