{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 4661
    },
    {
      "term": "OFF LABEL USE",
      "count": 4000
    },
    {
      "term": "PYREXIA",
      "count": 3419
    },
    {
      "term": "NAUSEA",
      "count": 2926
    },
    {
      "term": "DIARRHOEA",
      "count": 2863
    },
    {
      "term": "DRUG INTERACTION",
      "count": 2785
    },
    {
      "term": "FATIGUE",
      "count": 2527
    },
    {
      "term": "PAIN",
      "count": 2408
    },
    {
      "term": "HEADACHE",
      "count": 2324
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 2319
    },
    {
      "term": "PNEUMONIA",
      "count": 2295
    },
    {
      "term": "RASH",
      "count": 2014
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1924
    },
    {
      "term": "DYSPNOEA",
      "count": 1898
    },
    {
      "term": "VOMITING",
      "count": 1833
    },
    {
      "term": "DEATH",
      "count": 1825
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1731
    },
    {
      "term": "NEUTROPENIA",
      "count": 1642
    },
    {
      "term": "SEPSIS",
      "count": 1582
    },
    {
      "term": "ANAEMIA",
      "count": 1559
    },
    {
      "term": "RENAL FAILURE",
      "count": 1538
    },
    {
      "term": "ASTHENIA",
      "count": 1367
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1349
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 1336
    },
    {
      "term": "CONSTIPATION",
      "count": 1303
    },
    {
      "term": "INFECTION",
      "count": 1243
    },
    {
      "term": "DIZZINESS",
      "count": 1223
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1201
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1200
    },
    {
      "term": "MALAISE",
      "count": 1153
    },
    {
      "term": "PANCYTOPENIA",
      "count": 1151
    },
    {
      "term": "ANXIETY",
      "count": 1107
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1096
    },
    {
      "term": "HYPOTENSION",
      "count": 1082
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1078
    },
    {
      "term": "BACK PAIN",
      "count": 1038
    },
    {
      "term": "ARTHRALGIA",
      "count": 1021
    },
    {
      "term": "PRURITUS",
      "count": 1018
    },
    {
      "term": "HYPERTENSION",
      "count": 1013
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1008
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 968
    },
    {
      "term": "COUGH",
      "count": 964
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 943
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 941
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 929
    },
    {
      "term": "ERYTHEMA",
      "count": 914
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 881
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 874
    },
    {
      "term": "FALL",
      "count": 853
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 836
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 792
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 789
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 780
    },
    {
      "term": "DEHYDRATION",
      "count": 771
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 770
    },
    {
      "term": "DEPRESSION",
      "count": 750
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 750
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 750
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 716
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 708
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 696
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 680
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 676
    },
    {
      "term": "ASTHMA",
      "count": 673
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 666
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 658
    },
    {
      "term": "SINUSITIS",
      "count": 656
    },
    {
      "term": "CHEST PAIN",
      "count": 648
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 642
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 624
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 623
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 621
    },
    {
      "term": "DYSPHAGIA",
      "count": 619
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 617
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 614
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 611
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 604
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 603
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 602
    },
    {
      "term": "JOINT SWELLING",
      "count": 602
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 601
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 599
    },
    {
      "term": "RASH ERYTHEMATOUS",
      "count": 596
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 593
    },
    {
      "term": "LEUKOPENIA",
      "count": 590
    },
    {
      "term": "INSOMNIA",
      "count": 586
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 582
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 578
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 569
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 558
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 556
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 553
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 550
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 548
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 547
    },
    {
      "term": "OVERDOSE",
      "count": 546
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 541
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 540
    },
    {
      "term": "ALOPECIA",
      "count": 537
    },
    {
      "term": "SOMNOLENCE",
      "count": 536
    }
  ]
}