{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 3936
    },
    {
      "term": "OVERDOSE",
      "count": 2456
    },
    {
      "term": "DEATH",
      "count": 2080
    },
    {
      "term": "DRUG ABUSE",
      "count": 1765
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 1418
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 1288
    },
    {
      "term": "CARDIAC ARREST",
      "count": 924
    },
    {
      "term": "RESPIRATORY ARREST",
      "count": 748
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 738
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 633
    },
    {
      "term": "NAUSEA",
      "count": 624
    },
    {
      "term": "PAIN",
      "count": 586
    },
    {
      "term": "WRONG TECHNIQUE IN DRUG USAGE PROCESS",
      "count": 489
    },
    {
      "term": "OFF LABEL USE",
      "count": 469
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 458
    },
    {
      "term": "HYPOTENSION",
      "count": 452
    },
    {
      "term": "VOMITING",
      "count": 437
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 388
    },
    {
      "term": "DRUG INTERACTION",
      "count": 384
    },
    {
      "term": "DYSPNOEA",
      "count": 356
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 347
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 338
    },
    {
      "term": "DEPRESSION",
      "count": 332
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 322
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 312
    },
    {
      "term": "SOMNOLENCE",
      "count": 312
    },
    {
      "term": "PYREXIA",
      "count": 295
    },
    {
      "term": "CONSTIPATION",
      "count": 291
    },
    {
      "term": "ANXIETY",
      "count": 286
    },
    {
      "term": "HEADACHE",
      "count": 284
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 275
    },
    {
      "term": "INCORRECT ROUTE OF PRODUCT ADMINISTRATION",
      "count": 261
    },
    {
      "term": "MALAISE",
      "count": 261
    },
    {
      "term": "FATIGUE",
      "count": 256
    },
    {
      "term": "DIARRHOEA",
      "count": 255
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 254
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 237
    },
    {
      "term": "DYSPHAGIA",
      "count": 230
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 227
    },
    {
      "term": "DIZZINESS",
      "count": 224
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 218
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 214
    },
    {
      "term": "BACK PAIN",
      "count": 214
    },
    {
      "term": "PNEUMONIA",
      "count": 211
    },
    {
      "term": "BRADYCARDIA",
      "count": 205
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 202
    },
    {
      "term": "HYPERTENSION",
      "count": 199
    },
    {
      "term": "ANAEMIA",
      "count": 195
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 193
    },
    {
      "term": "ASTHENIA",
      "count": 191
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 184
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 181
    },
    {
      "term": "TACHYCARDIA",
      "count": 181
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 171
    },
    {
      "term": "AGITATION",
      "count": 165
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 165
    },
    {
      "term": "ARTHRALGIA",
      "count": 163
    },
    {
      "term": "PRODUCT ADHESION ISSUE",
      "count": 163
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 159
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 156
    },
    {
      "term": "ASTHMA",
      "count": 155
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 155
    },
    {
      "term": "SEPSIS",
      "count": 155
    },
    {
      "term": "DELIRIUM",
      "count": 153
    },
    {
      "term": "FALL",
      "count": 153
    },
    {
      "term": "INSOMNIA",
      "count": 149
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 147
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 146
    },
    {
      "term": "PREMATURE BABY",
      "count": 144
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 143
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 142
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 141
    },
    {
      "term": "RENAL FAILURE",
      "count": 141
    },
    {
      "term": "DECREASED APPETITE",
      "count": 140
    },
    {
      "term": "PRURITUS",
      "count": 140
    },
    {
      "term": "LEARNING DISORDER",
      "count": 139
    },
    {
      "term": "SPEECH DISORDER DEVELOPMENTAL",
      "count": 138
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 137
    },
    {
      "term": "DRUG PRESCRIBING ERROR",
      "count": 137
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 135
    },
    {
      "term": "COLITIS",
      "count": 129
    },
    {
      "term": "COMA",
      "count": 129
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 125
    },
    {
      "term": "ERYTHEMA",
      "count": 122
    },
    {
      "term": "HYPOXIA",
      "count": 122
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 121
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 119
    },
    {
      "term": "INCORRECT ROUTE OF DRUG ADMINISTRATION",
      "count": 118
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 117
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 115
    },
    {
      "term": "RASH",
      "count": 115
    },
    {
      "term": "DEHYDRATION",
      "count": 112
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 111
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 109
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 108
    },
    {
      "term": "MIOSIS",
      "count": 107
    },
    {
      "term": "DYSPEPSIA",
      "count": 105
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 104
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 104
    },
    {
      "term": "SEIZURE",
      "count": 104
    }
  ]
}