{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG RESISTANCE",
      "count": 204
    },
    {
      "term": "DRUG INTERACTION",
      "count": 198
    },
    {
      "term": "VIROLOGIC FAILURE",
      "count": 181
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 170
    },
    {
      "term": "VIRAL MUTATION IDENTIFIED",
      "count": 135
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 113
    },
    {
      "term": "DEATH",
      "count": 107
    },
    {
      "term": "LIPODYSTROPHY ACQUIRED",
      "count": 88
    },
    {
      "term": "CD4 LYMPHOCYTES DECREASED",
      "count": 85
    },
    {
      "term": "CD4/CD8 RATIO DECREASED",
      "count": 77
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 72
    },
    {
      "term": "MITOCHONDRIAL TOXICITY",
      "count": 72
    },
    {
      "term": "EYELID PTOSIS",
      "count": 71
    },
    {
      "term": "DIPLOPIA",
      "count": 70
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 61
    },
    {
      "term": "PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA",
      "count": 60
    },
    {
      "term": "OFF LABEL USE",
      "count": 59
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 56
    },
    {
      "term": "ANAEMIA",
      "count": 53
    },
    {
      "term": "RASH",
      "count": 53
    },
    {
      "term": "NAUSEA",
      "count": 50
    },
    {
      "term": "PYREXIA",
      "count": 47
    },
    {
      "term": "PREMATURE BABY",
      "count": 43
    },
    {
      "term": "DIARRHOEA",
      "count": 42
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 42
    },
    {
      "term": "RENAL FAILURE",
      "count": 41
    },
    {
      "term": "ASTHENIA",
      "count": 38
    },
    {
      "term": "PNEUMONIA",
      "count": 35
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 33
    },
    {
      "term": "DEPRESSION",
      "count": 32
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 32
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 32
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 31
    },
    {
      "term": "OPHTHALMOPLEGIA",
      "count": 30
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 29
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 28
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 28
    },
    {
      "term": "FATIGUE",
      "count": 28
    },
    {
      "term": "INSOMNIA",
      "count": 28
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 28
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 27
    },
    {
      "term": "AGITATION",
      "count": 26
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 26
    },
    {
      "term": "PANCYTOPENIA",
      "count": 26
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 26
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 26
    },
    {
      "term": "VOMITING",
      "count": 26
    },
    {
      "term": "ABORTION SPONTANEOUS",
      "count": 25
    },
    {
      "term": "CHEST PAIN",
      "count": 25
    },
    {
      "term": "CUSHING^S SYNDROME",
      "count": 25
    },
    {
      "term": "PAIN",
      "count": 25
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 24
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 24
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 24
    },
    {
      "term": "PANCREATITIS",
      "count": 23
    },
    {
      "term": "ERYTHEMA",
      "count": 22
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 22
    },
    {
      "term": "PARAESTHESIA",
      "count": 22
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 21
    },
    {
      "term": "HEADACHE",
      "count": 21
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 21
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 21
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 20
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 20
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 20
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 20
    },
    {
      "term": "VIRAL LOAD INCREASED",
      "count": 20
    },
    {
      "term": "NEUTROPENIA",
      "count": 19
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 19
    },
    {
      "term": "CD4 LYMPHOCYTES ABNORMAL",
      "count": 18
    },
    {
      "term": "DIZZINESS",
      "count": 18
    },
    {
      "term": "DRUG EXPOSURE DURING PREGNANCY",
      "count": 18
    },
    {
      "term": "EXOMPHALOS",
      "count": 18
    },
    {
      "term": "PROSTATE CANCER",
      "count": 18
    },
    {
      "term": "ANXIETY",
      "count": 17
    },
    {
      "term": "CHOLESTASIS",
      "count": 17
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 17
    },
    {
      "term": "DRUG LEVEL DECREASED",
      "count": 17
    },
    {
      "term": "HEPATITIS C",
      "count": 17
    },
    {
      "term": "OESOPHAGEAL CANDIDIASIS",
      "count": 17
    },
    {
      "term": "ADVERSE EVENT",
      "count": 16
    },
    {
      "term": "ARTHRALGIA",
      "count": 16
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 16
    },
    {
      "term": "BLOOD HIV RNA INCREASED",
      "count": 16
    },
    {
      "term": "BLOOD LACTIC ACID INCREASED",
      "count": 16
    },
    {
      "term": "DYSPHAGIA",
      "count": 16
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 16
    },
    {
      "term": "HYPERTENSION",
      "count": 16
    },
    {
      "term": "HYPOTENSION",
      "count": 16
    },
    {
      "term": "LEUKOPENIA",
      "count": 16
    },
    {
      "term": "PROTEINURIA",
      "count": 16
    },
    {
      "term": "SEPSIS",
      "count": 16
    },
    {
      "term": "BLADDER AGENESIS",
      "count": 15
    },
    {
      "term": "CYTOMEGALOVIRUS CHORIORETINITIS",
      "count": 15
    },
    {
      "term": "DYSPNOEA",
      "count": 15
    },
    {
      "term": "ENLARGED CLITORIS",
      "count": 15
    },
    {
      "term": "EXTRAOCULAR MUSCLE PARESIS",
      "count": 15
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 15
    },
    {
      "term": "IMMUNE RECONSTITUTION SYNDROME",
      "count": 15
    },
    {
      "term": "MYCOBACTERIAL INFECTION",
      "count": 15
    }
  ]
}