{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 212
    },
    {
      "term": "PYREXIA",
      "count": 166
    },
    {
      "term": "NAUSEA",
      "count": 128
    },
    {
      "term": "DRUG INTERACTION",
      "count": 121
    },
    {
      "term": "VOMITING",
      "count": 120
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 105
    },
    {
      "term": "COUGH",
      "count": 92
    },
    {
      "term": "DYSPNOEA",
      "count": 91
    },
    {
      "term": "OFF LABEL USE",
      "count": 91
    },
    {
      "term": "DIARRHOEA",
      "count": 89
    },
    {
      "term": "IMMUNE RECONSTITUTION SYNDROME",
      "count": 87
    },
    {
      "term": "ANAEMIA",
      "count": 82
    },
    {
      "term": "PNEUMONIA",
      "count": 78
    },
    {
      "term": "MYCOBACTERIUM AVIUM COMPLEX INFECTION",
      "count": 75
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 74
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 70
    },
    {
      "term": "FATIGUE",
      "count": 68
    },
    {
      "term": "RASH",
      "count": 68
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 68
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 66
    },
    {
      "term": "HEADACHE",
      "count": 65
    },
    {
      "term": "NEUTROPENIA",
      "count": 65
    },
    {
      "term": "DECREASED APPETITE",
      "count": 64
    },
    {
      "term": "PARADOXICAL DRUG REACTION",
      "count": 63
    },
    {
      "term": "ASTHENIA",
      "count": 62
    },
    {
      "term": "HEPATITIS",
      "count": 61
    },
    {
      "term": "TUBERCULOSIS",
      "count": 60
    },
    {
      "term": "ARTHRALGIA",
      "count": 54
    },
    {
      "term": "MALAISE",
      "count": 54
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 53
    },
    {
      "term": "PANCYTOPENIA",
      "count": 53
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 52
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 49
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 49
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 48
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 48
    },
    {
      "term": "DIZZINESS",
      "count": 47
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 46
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 44
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 43
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 43
    },
    {
      "term": "PRURITUS",
      "count": 43
    },
    {
      "term": "PULMONARY TUBERCULOSIS",
      "count": 43
    },
    {
      "term": "OPTIC NEURITIS",
      "count": 41
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 41
    },
    {
      "term": "JAUNDICE",
      "count": 40
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 38
    },
    {
      "term": "DEATH",
      "count": 38
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 38
    },
    {
      "term": "ACUTE HEPATIC FAILURE",
      "count": 36
    },
    {
      "term": "BLINDNESS",
      "count": 36
    },
    {
      "term": "VISION BLURRED",
      "count": 36
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 35
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 34
    },
    {
      "term": "SEPSIS",
      "count": 34
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 32
    },
    {
      "term": "HYPOTENSION",
      "count": 32
    },
    {
      "term": "ATYPICAL MYCOBACTERIAL INFECTION",
      "count": 31
    },
    {
      "term": "PAIN",
      "count": 31
    },
    {
      "term": "RENAL FAILURE",
      "count": 31
    },
    {
      "term": "LEUKOPENIA",
      "count": 30
    },
    {
      "term": "TINNITUS",
      "count": 30
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 29
    },
    {
      "term": "OPTIC NEUROPATHY",
      "count": 29
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 28
    },
    {
      "term": "DISSEMINATED TUBERCULOSIS",
      "count": 28
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 28
    },
    {
      "term": "VISUAL ACUITY REDUCED",
      "count": 28
    },
    {
      "term": "DYSPHONIA",
      "count": 27
    },
    {
      "term": "HYPERTENSION",
      "count": 27
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 27
    },
    {
      "term": "DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 26
    },
    {
      "term": "LIVER DISORDER",
      "count": 26
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 26
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 26
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 25
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 25
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 25
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 25
    },
    {
      "term": "CHEST PAIN",
      "count": 24
    },
    {
      "term": "COVID-19",
      "count": 24
    },
    {
      "term": "FALL",
      "count": 24
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 24
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 24
    },
    {
      "term": "HYPERTRANSAMINASAEMIA",
      "count": 24
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 24
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 23
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 23
    },
    {
      "term": "EOSINOPHILIA",
      "count": 23
    },
    {
      "term": "ERYTHEMA",
      "count": 23
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 23
    },
    {
      "term": "HAEMOPTYSIS",
      "count": 23
    },
    {
      "term": "HEPATIC ENCEPHALOPATHY",
      "count": 23
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 23
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 23
    },
    {
      "term": "BLOOD ALKALINE PHOSPHATASE INCREASED",
      "count": 22
    },
    {
      "term": "CHOLESTASIS",
      "count": 22
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 22
    },
    {
      "term": "MYALGIA",
      "count": 22
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 21
    }
  ]
}