{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3969
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 2429
    },
    {
      "term": "OFF LABEL USE",
      "count": 2098
    },
    {
      "term": "ARTHRALGIA",
      "count": 1811
    },
    {
      "term": "PAIN",
      "count": 1751
    },
    {
      "term": "FATIGUE",
      "count": 1523
    },
    {
      "term": "NAUSEA",
      "count": 1446
    },
    {
      "term": "HEADACHE",
      "count": 1377
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1309
    },
    {
      "term": "DIARRHOEA",
      "count": 1303
    },
    {
      "term": "RASH",
      "count": 1291
    },
    {
      "term": "JOINT SWELLING",
      "count": 1281
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 1242
    },
    {
      "term": "MALAISE",
      "count": 1145
    },
    {
      "term": "PNEUMONIA",
      "count": 1122
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 1050
    },
    {
      "term": "VOMITING",
      "count": 1016
    },
    {
      "term": "DYSPNOEA",
      "count": 1015
    },
    {
      "term": "PYREXIA",
      "count": 1004
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 994
    },
    {
      "term": "ALOPECIA",
      "count": 976
    },
    {
      "term": "SYNOVITIS",
      "count": 963
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 946
    },
    {
      "term": "PSORIATIC ARTHROPATHY",
      "count": 943
    },
    {
      "term": "ARTHROPATHY",
      "count": 926
    },
    {
      "term": "INFECTION",
      "count": 912
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 912
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 905
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 880
    },
    {
      "term": "DIZZINESS",
      "count": 880
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 834
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 833
    },
    {
      "term": "PRURITUS",
      "count": 826
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 813
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 809
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 806
    },
    {
      "term": "HYPERTENSION",
      "count": 803
    },
    {
      "term": "INSOMNIA",
      "count": 793
    },
    {
      "term": "ASTHENIA",
      "count": 789
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 757
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 756
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 751
    },
    {
      "term": "PEMPHIGUS",
      "count": 736
    },
    {
      "term": "SWELLING",
      "count": 722
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 716
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 713
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 709
    },
    {
      "term": "GLOSSODYNIA",
      "count": 700
    },
    {
      "term": "DECREASED APPETITE",
      "count": 688
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 682
    },
    {
      "term": "PSORIASIS",
      "count": 668
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 661
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 648
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 638
    },
    {
      "term": "HAND DEFORMITY",
      "count": 633
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 627
    },
    {
      "term": "ARTHRITIS",
      "count": 616
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 612
    },
    {
      "term": "WOUND",
      "count": 612
    },
    {
      "term": "FALL",
      "count": 607
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 596
    },
    {
      "term": "PERICARDITIS",
      "count": 593
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 576
    },
    {
      "term": "SEPSIS",
      "count": 548
    },
    {
      "term": "ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY POSITIVE",
      "count": 540
    },
    {
      "term": "DISCOMFORT",
      "count": 532
    },
    {
      "term": "COUGH",
      "count": 528
    },
    {
      "term": "INFLAMMATION",
      "count": 528
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 527
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 524
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 522
    },
    {
      "term": "STOMATITIS",
      "count": 513
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 508
    },
    {
      "term": "URTICARIA",
      "count": 505
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 504
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 501
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 478
    },
    {
      "term": "TYPE 2 DIABETES MELLITUS",
      "count": 477
    },
    {
      "term": "SINUSITIS",
      "count": 472
    },
    {
      "term": "FIBROMYALGIA",
      "count": 470
    },
    {
      "term": "LIVER INJURY",
      "count": 465
    },
    {
      "term": "BLISTER",
      "count": 464
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 456
    },
    {
      "term": "DEATH",
      "count": 452
    },
    {
      "term": "HELICOBACTER INFECTION",
      "count": 452
    },
    {
      "term": "INJURY",
      "count": 452
    },
    {
      "term": "SLEEP DISORDER",
      "count": 447
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 445
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 445
    },
    {
      "term": "DUODENAL ULCER PERFORATION",
      "count": 442
    },
    {
      "term": "DEPRESSION",
      "count": 441
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 436
    },
    {
      "term": "PULMONARY FIBROSIS",
      "count": 431
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 416
    },
    {
      "term": "FOLLICULITIS",
      "count": 408
    },
    {
      "term": "RHEUMATIC FEVER",
      "count": 404
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 400
    },
    {
      "term": "COVID-19",
      "count": 397
    },
    {
      "term": "GAIT INABILITY",
      "count": 397
    },
    {
      "term": "RHEUMATOID FACTOR POSITIVE",
      "count": 397
    }
  ]
}