{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MYELOSUPPRESSION",
      "count": 647
    },
    {
      "term": "NAUSEA",
      "count": 506
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 446
    },
    {
      "term": "VOMITING",
      "count": 405
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 362
    },
    {
      "term": "PYREXIA",
      "count": 334
    },
    {
      "term": "ASTHENIA",
      "count": 311
    },
    {
      "term": "NEUTROPENIA",
      "count": 285
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 256
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 251
    },
    {
      "term": "DIARRHOEA",
      "count": 228
    },
    {
      "term": "OFF LABEL USE",
      "count": 223
    },
    {
      "term": "FATIGUE",
      "count": 188
    },
    {
      "term": "DECREASED APPETITE",
      "count": 172
    },
    {
      "term": "ANAEMIA",
      "count": 163
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 157
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 140
    },
    {
      "term": "DYSPNOEA",
      "count": 132
    },
    {
      "term": "LEUKOPENIA",
      "count": 128
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 116
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 113
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 111
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 103
    },
    {
      "term": "ALOPECIA",
      "count": 100
    },
    {
      "term": "PAIN",
      "count": 95
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 94
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 93
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 91
    },
    {
      "term": "DIZZINESS",
      "count": 88
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 87
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 85
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 85
    },
    {
      "term": "PNEUMONIA",
      "count": 84
    },
    {
      "term": "LIVER INJURY",
      "count": 81
    },
    {
      "term": "BACK PAIN",
      "count": 79
    },
    {
      "term": "HEADACHE",
      "count": 77
    },
    {
      "term": "PANCYTOPENIA",
      "count": 76
    },
    {
      "term": "CONSTIPATION",
      "count": 74
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 74
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 72
    },
    {
      "term": "DYSPHAGIA",
      "count": 71
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 71
    },
    {
      "term": "DEATH",
      "count": 70
    },
    {
      "term": "RASH",
      "count": 70
    },
    {
      "term": "MALAISE",
      "count": 69
    },
    {
      "term": "SEPSIS",
      "count": 69
    },
    {
      "term": "PARAESTHESIA",
      "count": 68
    },
    {
      "term": "INFECTION",
      "count": 66
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 66
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 65
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 64
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 63
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 63
    },
    {
      "term": "METASTASES TO BONE",
      "count": 63
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 62
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 62
    },
    {
      "term": "CARDIOTOXICITY",
      "count": 62
    },
    {
      "term": "DEHYDRATION",
      "count": 62
    },
    {
      "term": "GRANULOCYTE COUNT DECREASED",
      "count": 62
    },
    {
      "term": "COUGH",
      "count": 61
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 60
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 56
    },
    {
      "term": "BREAST CANCER",
      "count": 54
    },
    {
      "term": "EJECTION FRACTION DECREASED",
      "count": 53
    },
    {
      "term": "PALPITATIONS",
      "count": 53
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 52
    },
    {
      "term": "ARTHRALGIA",
      "count": 51
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 51
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 50
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 49
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 48
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 47
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 47
    },
    {
      "term": "CHEST PAIN",
      "count": 46
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 46
    },
    {
      "term": "MYALGIA",
      "count": 46
    },
    {
      "term": "BREAST CANCER METASTATIC",
      "count": 45
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 45
    },
    {
      "term": "STOMATITIS",
      "count": 45
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 44
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 44
    },
    {
      "term": "DISCOMFORT",
      "count": 42
    },
    {
      "term": "ERYTHEMA",
      "count": 42
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 42
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 41
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 41
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 40
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 40
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 39
    },
    {
      "term": "CARDIOMYOPATHY",
      "count": 39
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 38
    },
    {
      "term": "RHINORRHOEA",
      "count": 38
    },
    {
      "term": "CHILLS",
      "count": 37
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 36
    },
    {
      "term": "HYPOTENSION",
      "count": 36
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 36
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 35
    },
    {
      "term": "LEFT VENTRICULAR DYSFUNCTION",
      "count": 35
    },
    {
      "term": "CARDIAC DYSFUNCTION",
      "count": 33
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 32
    }
  ]
}