{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 417
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 360
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 359
    },
    {
      "term": "DEATH",
      "count": 322
    },
    {
      "term": "HEPATITIS B",
      "count": 261
    },
    {
      "term": "DIARRHOEA",
      "count": 259
    },
    {
      "term": "PYREXIA",
      "count": 258
    },
    {
      "term": "FATIGUE",
      "count": 241
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 233
    },
    {
      "term": "PNEUMONIA",
      "count": 214
    },
    {
      "term": "NAUSEA",
      "count": 210
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 176
    },
    {
      "term": "ANAEMIA",
      "count": 170
    },
    {
      "term": "ASTHENIA",
      "count": 169
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 159
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 159
    },
    {
      "term": "NEUTROPENIA",
      "count": 155
    },
    {
      "term": "HEPATITIS B REACTIVATION",
      "count": 153
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 151
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 149
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 144
    },
    {
      "term": "DECREASED APPETITE",
      "count": 142
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 140
    },
    {
      "term": "VIRAL MUTATION IDENTIFIED",
      "count": 136
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 133
    },
    {
      "term": "HEADACHE",
      "count": 132
    },
    {
      "term": "HEPATOCELLULAR CARCINOMA",
      "count": 132
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 130
    },
    {
      "term": "DYSPNOEA",
      "count": 129
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 127
    },
    {
      "term": "PAIN",
      "count": 124
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 121
    },
    {
      "term": "VOMITING",
      "count": 116
    },
    {
      "term": "RASH",
      "count": 108
    },
    {
      "term": "ASCITES",
      "count": 105
    },
    {
      "term": "RENAL FAILURE",
      "count": 104
    },
    {
      "term": "DRUG INTERACTION",
      "count": 103
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 102
    },
    {
      "term": "DIZZINESS",
      "count": 101
    },
    {
      "term": "COVID-19",
      "count": 99
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 99
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 99
    },
    {
      "term": "SEPSIS",
      "count": 96
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 94
    },
    {
      "term": "HEPATIC CIRRHOSIS",
      "count": 94
    },
    {
      "term": "ARTHRALGIA",
      "count": 93
    },
    {
      "term": "MALAISE",
      "count": 90
    },
    {
      "term": "VIRAL LOAD INCREASED",
      "count": 90
    },
    {
      "term": "HEPATITIS B DNA INCREASED",
      "count": 89
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 89
    },
    {
      "term": "HYPERTENSION",
      "count": 88
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 88
    },
    {
      "term": "HOSPITALISATION",
      "count": 84
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 83
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 81
    },
    {
      "term": "BACK PAIN",
      "count": 80
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 80
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 79
    },
    {
      "term": "PRURITUS",
      "count": 78
    },
    {
      "term": "CONSTIPATION",
      "count": 77
    },
    {
      "term": "LEUKOPENIA",
      "count": 77
    },
    {
      "term": "INFECTION",
      "count": 76
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 75
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 74
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 74
    },
    {
      "term": "HYPOTENSION",
      "count": 74
    },
    {
      "term": "COUGH",
      "count": 71
    },
    {
      "term": "FALL",
      "count": 71
    },
    {
      "term": "VIRAL INFECTION",
      "count": 71
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 70
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 70
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 67
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 65
    },
    {
      "term": "HEPATIC ENCEPHALOPATHY",
      "count": 64
    },
    {
      "term": "BONE PAIN",
      "count": 62
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 60
    },
    {
      "term": "JAUNDICE",
      "count": 60
    },
    {
      "term": "CHILLS",
      "count": 59
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 59
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 59
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 59
    },
    {
      "term": "MYALGIA",
      "count": 58
    },
    {
      "term": "OSTEOMALACIA",
      "count": 58
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 57
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 57
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 57
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 56
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 55
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 55
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 54
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 54
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 54
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 52
    },
    {
      "term": "PROTEINURIA",
      "count": 52
    },
    {
      "term": "ANXIETY",
      "count": 51
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 51
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 51
    },
    {
      "term": "FANCONI SYNDROME ACQUIRED",
      "count": 50
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 50
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 50
    }
  ]
}