{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 163
    },
    {
      "term": "ANAEMIA",
      "count": 65
    },
    {
      "term": "FATIGUE",
      "count": 53
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 53
    },
    {
      "term": "OFF LABEL USE",
      "count": 49
    },
    {
      "term": "DIARRHOEA",
      "count": 48
    },
    {
      "term": "ARTHRALGIA",
      "count": 45
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 38
    },
    {
      "term": "DEATH",
      "count": 38
    },
    {
      "term": "NAUSEA",
      "count": 36
    },
    {
      "term": "PYREXIA",
      "count": 36
    },
    {
      "term": "RASH",
      "count": 35
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 33
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 33
    },
    {
      "term": "NEUTROPENIA",
      "count": 32
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 31
    },
    {
      "term": "ASTHENIA",
      "count": 31
    },
    {
      "term": "DYSPNOEA",
      "count": 30
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 29
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 28
    },
    {
      "term": "TOXIC SKIN ERUPTION",
      "count": 27
    },
    {
      "term": "VOMITING",
      "count": 26
    },
    {
      "term": "SEPSIS",
      "count": 23
    },
    {
      "term": "PNEUMONITIS",
      "count": 21
    },
    {
      "term": "COLITIS",
      "count": 19
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 19
    },
    {
      "term": "IMMUNOTOXICITY",
      "count": 19
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 19
    },
    {
      "term": "LUNG DISORDER",
      "count": 19
    },
    {
      "term": "PNEUMONIA",
      "count": 18
    },
    {
      "term": "PRURITUS",
      "count": 18
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 17
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 16
    },
    {
      "term": "MYOCARDITIS",
      "count": 16
    },
    {
      "term": "PAIN",
      "count": 16
    },
    {
      "term": "DECREASED APPETITE",
      "count": 14
    },
    {
      "term": "DERMATITIS BULLOUS",
      "count": 14
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 14
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 14
    },
    {
      "term": "ERYTHEMA",
      "count": 14
    },
    {
      "term": "ISCHAEMIC STROKE",
      "count": 14
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 14
    },
    {
      "term": "SKIN TOXICITY",
      "count": 14
    },
    {
      "term": "DIABETIC KETOACIDOSIS",
      "count": 13
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 13
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 13
    },
    {
      "term": "RENAL FAILURE",
      "count": 13
    },
    {
      "term": "COVID-19",
      "count": 12
    },
    {
      "term": "ENDOMETRIAL CANCER",
      "count": 12
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 12
    },
    {
      "term": "IMMUNE-MEDIATED LUNG DISEASE",
      "count": 12
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 12
    },
    {
      "term": "POLYMYALGIA RHEUMATICA",
      "count": 12
    },
    {
      "term": "AUTOIMMUNE HAEMOLYTIC ANAEMIA",
      "count": 11
    },
    {
      "term": "DEHYDRATION",
      "count": 11
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 11
    },
    {
      "term": "ENDOMETRIAL CANCER RECURRENT",
      "count": 11
    },
    {
      "term": "HYPERTHYROIDISM",
      "count": 11
    },
    {
      "term": "IMMUNE-MEDIATED ENTEROCOLITIS",
      "count": 11
    },
    {
      "term": "IMMUNE-MEDIATED MYOCARDITIS",
      "count": 11
    },
    {
      "term": "MALAISE",
      "count": 11
    },
    {
      "term": "PANCYTOPENIA",
      "count": 11
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 11
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 10
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 10
    },
    {
      "term": "AUTOIMMUNE HEPATITIS",
      "count": 10
    },
    {
      "term": "CARDIAC ARREST",
      "count": 10
    },
    {
      "term": "HYPOTENSION",
      "count": 10
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 10
    },
    {
      "term": "MYOSITIS",
      "count": 10
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 10
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 10
    },
    {
      "term": "CONSTIPATION",
      "count": 9
    },
    {
      "term": "DRY MOUTH",
      "count": 9
    },
    {
      "term": "FLUSHING",
      "count": 9
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 9
    },
    {
      "term": "HEPATITIS",
      "count": 9
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 9
    },
    {
      "term": "TROPONIN INCREASED",
      "count": 9
    },
    {
      "term": "ALOPECIA",
      "count": 8
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 8
    },
    {
      "term": "DYSPHAGIA",
      "count": 8
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 8
    },
    {
      "term": "IMMUNE-MEDIATED ARTHRITIS",
      "count": 8
    },
    {
      "term": "IMMUNE-MEDIATED HEPATITIS",
      "count": 8
    },
    {
      "term": "INTESTINAL OBSTRUCTION",
      "count": 8
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 8
    },
    {
      "term": "MYALGIA",
      "count": 8
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 8
    },
    {
      "term": "PERITONEAL NEOPLASM",
      "count": 8
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 8
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 8
    },
    {
      "term": "ANXIETY",
      "count": 7
    },
    {
      "term": "ASCITES",
      "count": 7
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 7
    },
    {
      "term": "COUGH",
      "count": 7
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 7
    },
    {
      "term": "DRUG ERUPTION",
      "count": 7
    },
    {
      "term": "ENCEPHALITIS",
      "count": 7
    },
    {
      "term": "GASTRITIS",
      "count": 7
    }
  ]
}