{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 111
    },
    {
      "term": "EYE IRRITATION",
      "count": 80
    },
    {
      "term": "OFF LABEL USE",
      "count": 58
    },
    {
      "term": "OCULAR HYPERAEMIA",
      "count": 47
    },
    {
      "term": "FATIGUE",
      "count": 46
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 45
    },
    {
      "term": "GLAUCOMA",
      "count": 45
    },
    {
      "term": "VISION BLURRED",
      "count": 45
    },
    {
      "term": "EYE PAIN",
      "count": 41
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 39
    },
    {
      "term": "PRODUCT CONTAINER ISSUE",
      "count": 38
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 37
    },
    {
      "term": "PNEUMONIA",
      "count": 36
    },
    {
      "term": "HYPERTENSION",
      "count": 35
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 33
    },
    {
      "term": "DIARRHOEA",
      "count": 32
    },
    {
      "term": "PAIN",
      "count": 32
    },
    {
      "term": "VOMITING",
      "count": 32
    },
    {
      "term": "ARTHRALGIA",
      "count": 31
    },
    {
      "term": "DYSPNOEA",
      "count": 31
    },
    {
      "term": "HEADACHE",
      "count": 31
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 31
    },
    {
      "term": "INTRAOCULAR PRESSURE INCREASED",
      "count": 31
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 31
    },
    {
      "term": "DIZZINESS",
      "count": 30
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 30
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 29
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 29
    },
    {
      "term": "NAUSEA",
      "count": 29
    },
    {
      "term": "DEATH",
      "count": 27
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 26
    },
    {
      "term": "ASTHENIA",
      "count": 25
    },
    {
      "term": "RASH",
      "count": 25
    },
    {
      "term": "BRONCHITIS",
      "count": 24
    },
    {
      "term": "COLITIS MICROSCOPIC",
      "count": 23
    },
    {
      "term": "DIVERTICULITIS",
      "count": 23
    },
    {
      "term": "FALL",
      "count": 23
    },
    {
      "term": "SYNOVITIS",
      "count": 22
    },
    {
      "term": "EYE PRURITUS",
      "count": 20
    },
    {
      "term": "PRURITUS",
      "count": 19
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 18
    },
    {
      "term": "INSOMNIA",
      "count": 18
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 18
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 18
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 17
    },
    {
      "term": "MALAISE",
      "count": 17
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 17
    },
    {
      "term": "PRODUCT DELIVERY MECHANISM ISSUE",
      "count": 17
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 17
    },
    {
      "term": "SCIATICA",
      "count": 17
    },
    {
      "term": "SKIN REACTION",
      "count": 17
    },
    {
      "term": "THYROID DISORDER",
      "count": 17
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 17
    },
    {
      "term": "CATARACT",
      "count": 16
    },
    {
      "term": "COUGH",
      "count": 16
    },
    {
      "term": "DYSGEUSIA",
      "count": 16
    },
    {
      "term": "ERYTHEMA",
      "count": 16
    },
    {
      "term": "EYE SWELLING",
      "count": 16
    },
    {
      "term": "PYREXIA",
      "count": 16
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 15
    },
    {
      "term": "CONSTIPATION",
      "count": 15
    },
    {
      "term": "COVID-19",
      "count": 15
    },
    {
      "term": "INJECTION SITE REACTION",
      "count": 15
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 15
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 15
    },
    {
      "term": "BURNING SENSATION",
      "count": 14
    },
    {
      "term": "HAND DEFORMITY",
      "count": 14
    },
    {
      "term": "PRODUCT STORAGE ERROR",
      "count": 14
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 14
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 13
    },
    {
      "term": "HOT FLUSH",
      "count": 13
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 13
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 13
    },
    {
      "term": "INSTILLATION SITE PAIN",
      "count": 13
    },
    {
      "term": "LACRIMATION INCREASED",
      "count": 13
    },
    {
      "term": "LIQUID PRODUCT PHYSICAL ISSUE",
      "count": 13
    },
    {
      "term": "OCULAR DISCOMFORT",
      "count": 13
    },
    {
      "term": "DISCOMFORT",
      "count": 12
    },
    {
      "term": "HALLUCINATION",
      "count": 12
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 12
    },
    {
      "term": "PRODUCT PACKAGING QUANTITY ISSUE",
      "count": 12
    },
    {
      "term": "BACK PAIN",
      "count": 11
    },
    {
      "term": "BLINDNESS",
      "count": 11
    },
    {
      "term": "DECREASED APPETITE",
      "count": 11
    },
    {
      "term": "DRUG INTERACTION",
      "count": 11
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 11
    },
    {
      "term": "HYPOTENSION",
      "count": 11
    },
    {
      "term": "MYALGIA",
      "count": 11
    },
    {
      "term": "SOMNOLENCE",
      "count": 11
    },
    {
      "term": "DRY EYE",
      "count": 10
    },
    {
      "term": "PRODUCT PACKAGING ISSUE",
      "count": 10
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 9
    },
    {
      "term": "BRADYCARDIA",
      "count": 9
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 9
    },
    {
      "term": "INJECTION SITE PAIN",
      "count": 9
    },
    {
      "term": "INSTILLATION SITE IRRITATION",
      "count": 9
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 9
    },
    {
      "term": "PRODUCT RESIDUE PRESENT",
      "count": 9
    },
    {
      "term": "SINUSITIS",
      "count": 9
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 9
    }
  ]
}