{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "TREATMENT FAILURE",
      "count": 2281
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1479
    },
    {
      "term": "EYE IRRITATION",
      "count": 803
    },
    {
      "term": "OFF LABEL USE",
      "count": 745
    },
    {
      "term": "EYE PAIN",
      "count": 700
    },
    {
      "term": "FATIGUE",
      "count": 650
    },
    {
      "term": "HEADACHE",
      "count": 543
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 513
    },
    {
      "term": "VISION BLURRED",
      "count": 504
    },
    {
      "term": "PAIN",
      "count": 462
    },
    {
      "term": "OCULAR HYPERAEMIA",
      "count": 437
    },
    {
      "term": "INTRAOCULAR PRESSURE INCREASED",
      "count": 427
    },
    {
      "term": "GLAUCOMA",
      "count": 421
    },
    {
      "term": "DIARRHOEA",
      "count": 414
    },
    {
      "term": "DYSPNOEA",
      "count": 408
    },
    {
      "term": "DIZZINESS",
      "count": 406
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 396
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 387
    },
    {
      "term": "RASH",
      "count": 363
    },
    {
      "term": "NAUSEA",
      "count": 350
    },
    {
      "term": "DEATH",
      "count": 344
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 329
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 326
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 305
    },
    {
      "term": "ASTHENIA",
      "count": 303
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 293
    },
    {
      "term": "FALL",
      "count": 290
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 288
    },
    {
      "term": "PNEUMONIA",
      "count": 271
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 270
    },
    {
      "term": "PYREXIA",
      "count": 268
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 267
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 260
    },
    {
      "term": "SOMNOLENCE",
      "count": 259
    },
    {
      "term": "VOMITING",
      "count": 258
    },
    {
      "term": "HYPERTENSION",
      "count": 247
    },
    {
      "term": "DYSGEUSIA",
      "count": 245
    },
    {
      "term": "COVID-19",
      "count": 239
    },
    {
      "term": "DEPRESSION",
      "count": 238
    },
    {
      "term": "PRURITUS",
      "count": 235
    },
    {
      "term": "ARTHRALGIA",
      "count": 229
    },
    {
      "term": "EYE PRURITUS",
      "count": 227
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 227
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 220
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 215
    },
    {
      "term": "PRODUCT CONTAINER ISSUE",
      "count": 212
    },
    {
      "term": "COUGH",
      "count": 210
    },
    {
      "term": "CONSTIPATION",
      "count": 208
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 206
    },
    {
      "term": "PALPITATIONS",
      "count": 202
    },
    {
      "term": "MALAISE",
      "count": 195
    },
    {
      "term": "ARTHRITIS",
      "count": 192
    },
    {
      "term": "LACRIMATION INCREASED",
      "count": 188
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 178
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 178
    },
    {
      "term": "VERTIGO",
      "count": 174
    },
    {
      "term": "DECREASED APPETITE",
      "count": 172
    },
    {
      "term": "TINNITUS",
      "count": 171
    },
    {
      "term": "STRESS",
      "count": 170
    },
    {
      "term": "BRONCHITIS",
      "count": 167
    },
    {
      "term": "MIGRAINE",
      "count": 167
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 167
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 165
    },
    {
      "term": "BACK PAIN",
      "count": 163
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 163
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 163
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 162
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 161
    },
    {
      "term": "CATARACT",
      "count": 159
    },
    {
      "term": "EYE SWELLING",
      "count": 159
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 157
    },
    {
      "term": "INSOMNIA",
      "count": 157
    },
    {
      "term": "SWOLLEN TONGUE",
      "count": 154
    },
    {
      "term": "NIGHTMARE",
      "count": 153
    },
    {
      "term": "ECZEMA",
      "count": 152
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 151
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 151
    },
    {
      "term": "DRY EYE",
      "count": 148
    },
    {
      "term": "MEDICATION ERROR",
      "count": 148
    },
    {
      "term": "GINGIVAL PAIN",
      "count": 144
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 142
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 142
    },
    {
      "term": "BRONCHIECTASIS",
      "count": 141
    },
    {
      "term": "ERYTHEMA",
      "count": 140
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 139
    },
    {
      "term": "HYPOTENSION",
      "count": 139
    },
    {
      "term": "PAROSMIA",
      "count": 139
    },
    {
      "term": "RHINITIS",
      "count": 138
    },
    {
      "term": "SYSTEMIC LUPUS ERYTHEMATOSUS",
      "count": 137
    },
    {
      "term": "BURNS SECOND DEGREE",
      "count": 136
    },
    {
      "term": "CARDIAC MURMUR",
      "count": 136
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 136
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 136
    },
    {
      "term": "DIVERTICULITIS",
      "count": 135
    },
    {
      "term": "HYPOPNOEA",
      "count": 135
    },
    {
      "term": "IMPAIRED WORK ABILITY",
      "count": 135
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 135
    },
    {
      "term": "CATARRH",
      "count": 133
    },
    {
      "term": "IMPAIRED QUALITY OF LIFE",
      "count": 133
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 133
    }
  ]
}