{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2273
    },
    {
      "term": "FATIGUE",
      "count": 868
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 814
    },
    {
      "term": "HEADACHE",
      "count": 773
    },
    {
      "term": "ANXIETY",
      "count": 671
    },
    {
      "term": "NAUSEA",
      "count": 671
    },
    {
      "term": "SOMNOLENCE",
      "count": 523
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 518
    },
    {
      "term": "DEPRESSION",
      "count": 501
    },
    {
      "term": "DISTURBANCE IN ATTENTION",
      "count": 451
    },
    {
      "term": "INSOMNIA",
      "count": 396
    },
    {
      "term": "DRUG SCREEN POSITIVE",
      "count": 376
    },
    {
      "term": "DIZZINESS",
      "count": 367
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 328
    },
    {
      "term": "OFF LABEL USE",
      "count": 322
    },
    {
      "term": "PAIN",
      "count": 322
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 313
    },
    {
      "term": "DRUG DIVERSION",
      "count": 307
    },
    {
      "term": "DRUG ABUSE",
      "count": 293
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 289
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 287
    },
    {
      "term": "IRRITABILITY",
      "count": 272
    },
    {
      "term": "VOMITING",
      "count": 264
    },
    {
      "term": "MALAISE",
      "count": 263
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 238
    },
    {
      "term": "DIARRHOEA",
      "count": 237
    },
    {
      "term": "DYSPNOEA",
      "count": 237
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 229
    },
    {
      "term": "FALL",
      "count": 221
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 221
    },
    {
      "term": "RASH",
      "count": 216
    },
    {
      "term": "ASTHENIA",
      "count": 210
    },
    {
      "term": "IMPAIRED DRIVING ABILITY",
      "count": 204
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 192
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 190
    },
    {
      "term": "PALPITATIONS",
      "count": 188
    },
    {
      "term": "AGITATION",
      "count": 187
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 182
    },
    {
      "term": "HYPERTENSION",
      "count": 181
    },
    {
      "term": "OVERDOSE",
      "count": 178
    },
    {
      "term": "MIGRAINE",
      "count": 176
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 173
    },
    {
      "term": "TREMOR",
      "count": 171
    },
    {
      "term": "DECREASED APPETITE",
      "count": 165
    },
    {
      "term": "ROAD TRAFFIC ACCIDENT",
      "count": 165
    },
    {
      "term": "ARTHRALGIA",
      "count": 164
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 161
    },
    {
      "term": "PRURITUS",
      "count": 159
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 158
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 155
    },
    {
      "term": "INTENTIONAL OVERDOSE",
      "count": 149
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 148
    },
    {
      "term": "THERAPEUTIC RESPONSE CHANGED",
      "count": 147
    },
    {
      "term": "BRAIN FOG",
      "count": 145
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 144
    },
    {
      "term": "AGGRESSION",
      "count": 144
    },
    {
      "term": "DRUG INTERACTION",
      "count": 139
    },
    {
      "term": "LETHARGY",
      "count": 139
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 137
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 135
    },
    {
      "term": "VISION BLURRED",
      "count": 133
    },
    {
      "term": "BACK PAIN",
      "count": 131
    },
    {
      "term": "CONSTIPATION",
      "count": 131
    },
    {
      "term": "DEATH",
      "count": 129
    },
    {
      "term": "CHEST PAIN",
      "count": 128
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 128
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 126
    },
    {
      "term": "PRODUCT ADMINISTRATION INTERRUPTED",
      "count": 125
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 125
    },
    {
      "term": "ANGER",
      "count": 124
    },
    {
      "term": "LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES",
      "count": 121
    },
    {
      "term": "DRY MOUTH",
      "count": 118
    },
    {
      "term": "PARAESTHESIA",
      "count": 117
    },
    {
      "term": "PRODUCT PHYSICAL ISSUE",
      "count": 116
    },
    {
      "term": "SLEEP DISORDER",
      "count": 115
    },
    {
      "term": "ILLNESS",
      "count": 114
    },
    {
      "term": "COVID-19",
      "count": 112
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 111
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 110
    },
    {
      "term": "SURGERY",
      "count": 109
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 108
    },
    {
      "term": "TACHYCARDIA",
      "count": 108
    },
    {
      "term": "ABNORMAL BEHAVIOUR",
      "count": 107
    },
    {
      "term": "CARDIAC ARREST",
      "count": 107
    },
    {
      "term": "DRUG EFFECT DECREASED",
      "count": 107
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 107
    },
    {
      "term": "SEIZURE",
      "count": 106
    },
    {
      "term": "STRESS",
      "count": 106
    },
    {
      "term": "DEPRESSED MOOD",
      "count": 104
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 102
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 102
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 102
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 102
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 101
    },
    {
      "term": "ADVERSE EVENT",
      "count": 100
    },
    {
      "term": "COUGH",
      "count": 97
    },
    {
      "term": "HOMICIDE",
      "count": 94
    },
    {
      "term": "MYALGIA",
      "count": 94
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 94
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 94
    }
  ]
}