{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "BRADYCARDIA",
      "count": 188
    },
    {
      "term": "OFF LABEL USE",
      "count": 161
    },
    {
      "term": "CARDIAC ARREST",
      "count": 110
    },
    {
      "term": "HYPOTENSION",
      "count": 94
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 87
    },
    {
      "term": "DRUG INTERACTION",
      "count": 75
    },
    {
      "term": "PRODUCT ADMINISTERED TO PATIENT OF INAPPROPRIATE AGE",
      "count": 71
    },
    {
      "term": "PYREXIA",
      "count": 69
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 64
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 57
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 56
    },
    {
      "term": "DIABETES INSIPIDUS",
      "count": 55
    },
    {
      "term": "ARTERIOSPASM CORONARY",
      "count": 50
    },
    {
      "term": "AGITATION",
      "count": 48
    },
    {
      "term": "OVERDOSE",
      "count": 45
    },
    {
      "term": "TACHYCARDIA",
      "count": 43
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 42
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 41
    },
    {
      "term": "PNEUMONIA",
      "count": 39
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 39
    },
    {
      "term": "RESPIRATORY DEPRESSION",
      "count": 38
    },
    {
      "term": "DRUG ADMINISTERED TO PATIENT OF INAPPROPRIATE AGE",
      "count": 37
    },
    {
      "term": "SOMNOLENCE",
      "count": 36
    },
    {
      "term": "TORSADE DE POINTES",
      "count": 36
    },
    {
      "term": "GENERALISED TONIC-CLONIC SEIZURE",
      "count": 35
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 34
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 34
    },
    {
      "term": "HYPERTENSION",
      "count": 34
    },
    {
      "term": "HYPERTHERMIA",
      "count": 33
    },
    {
      "term": "DELIRIUM",
      "count": 32
    },
    {
      "term": "DYSPNOEA",
      "count": 32
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 31
    },
    {
      "term": "SINUS BRADYCARDIA",
      "count": 31
    },
    {
      "term": "UPPER AIRWAY OBSTRUCTION",
      "count": 31
    },
    {
      "term": "HYPOXIA",
      "count": 30
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 30
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 29
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 28
    },
    {
      "term": "SEDATION COMPLICATION",
      "count": 28
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 28
    },
    {
      "term": "VENTRICULAR TACHYCARDIA",
      "count": 28
    },
    {
      "term": "VOMITING",
      "count": 28
    },
    {
      "term": "APNOEA",
      "count": 27
    },
    {
      "term": "SEIZURE",
      "count": 26
    },
    {
      "term": "SINUS ARREST",
      "count": 26
    },
    {
      "term": "MYOCLONUS",
      "count": 25
    },
    {
      "term": "NAUSEA",
      "count": 25
    },
    {
      "term": "SEPSIS",
      "count": 25
    },
    {
      "term": "SYNCOPE",
      "count": 25
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 24
    },
    {
      "term": "ATRIOVENTRICULAR BLOCK COMPLETE",
      "count": 24
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 22
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 22
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 22
    },
    {
      "term": "SEIZURE LIKE PHENOMENA",
      "count": 22
    },
    {
      "term": "TACHYPNOEA",
      "count": 22
    },
    {
      "term": "DRUG WITHDRAWAL CONVULSIONS",
      "count": 21
    },
    {
      "term": "DEATH",
      "count": 20
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 20
    },
    {
      "term": "FLOPPY IRIS SYNDROME",
      "count": 20
    },
    {
      "term": "HYPOTONIA",
      "count": 20
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 20
    },
    {
      "term": "HYPOCAPNIA",
      "count": 19
    },
    {
      "term": "POLYURIA",
      "count": 19
    },
    {
      "term": "ATRIOVENTRICULAR BLOCK SECOND DEGREE",
      "count": 18
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 18
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 18
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 18
    },
    {
      "term": "HEART RATE DECREASED",
      "count": 18
    },
    {
      "term": "ANAEMIA",
      "count": 17
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 17
    },
    {
      "term": "HYPOTHERMIA",
      "count": 17
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 17
    },
    {
      "term": "RENAL FAILURE",
      "count": 17
    },
    {
      "term": "BLOOD LACTIC ACID INCREASED",
      "count": 16
    },
    {
      "term": "DIARRHOEA",
      "count": 16
    },
    {
      "term": "HYPERTHERMIA MALIGNANT",
      "count": 16
    },
    {
      "term": "INTESTINAL PSEUDO-OBSTRUCTION",
      "count": 16
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 16
    },
    {
      "term": "SEDATION",
      "count": 16
    },
    {
      "term": "WRONG PRODUCT ADMINISTERED",
      "count": 16
    },
    {
      "term": "ILEUS",
      "count": 15
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 15
    },
    {
      "term": "RESPIRATORY ACIDOSIS",
      "count": 15
    },
    {
      "term": "SHOCK",
      "count": 15
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 15
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 14
    },
    {
      "term": "HYPERNATRAEMIA",
      "count": 14
    },
    {
      "term": "HYPERPYREXIA",
      "count": 14
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 14
    },
    {
      "term": "OBSTRUCTIVE AIRWAYS DISORDER",
      "count": 14
    },
    {
      "term": "PAIN",
      "count": 14
    },
    {
      "term": "RENAL ISCHAEMIA",
      "count": 14
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 14
    },
    {
      "term": "RESTLESSNESS",
      "count": 14
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 14
    },
    {
      "term": "BRADYARRHYTHMIA",
      "count": 13
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 13
    },
    {
      "term": "GLOSSOPTOSIS",
      "count": 13
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 13
    }
  ]
}