{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 1111
    },
    {
      "term": "PYREXIA",
      "count": 695
    },
    {
      "term": "NAUSEA",
      "count": 688
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 635
    },
    {
      "term": "ANAEMIA",
      "count": 562
    },
    {
      "term": "DIARRHOEA",
      "count": 519
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 492
    },
    {
      "term": "PNEUMONIA",
      "count": 476
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 467
    },
    {
      "term": "NEUTROPENIA",
      "count": 466
    },
    {
      "term": "VOMITING",
      "count": 463
    },
    {
      "term": "DYSPNOEA",
      "count": 461
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 455
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 453
    },
    {
      "term": "FATIGUE",
      "count": 443
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 437
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 432
    },
    {
      "term": "DECREASED APPETITE",
      "count": 409
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 371
    },
    {
      "term": "RASH",
      "count": 364
    },
    {
      "term": "DEATH",
      "count": 343
    },
    {
      "term": "PAIN",
      "count": 323
    },
    {
      "term": "CONSTIPATION",
      "count": 294
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 292
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 282
    },
    {
      "term": "HEADACHE",
      "count": 281
    },
    {
      "term": "MALAISE",
      "count": 281
    },
    {
      "term": "ASTHENIA",
      "count": 279
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 274
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 240
    },
    {
      "term": "SEPSIS",
      "count": 235
    },
    {
      "term": "ALOPECIA",
      "count": 234
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 233
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 228
    },
    {
      "term": "PRURITUS",
      "count": 223
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 222
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 221
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 216
    },
    {
      "term": "DIZZINESS",
      "count": 209
    },
    {
      "term": "STOMATITIS",
      "count": 205
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 202
    },
    {
      "term": "INFECTION",
      "count": 200
    },
    {
      "term": "COUGH",
      "count": 197
    },
    {
      "term": "ARTHRALGIA",
      "count": 192
    },
    {
      "term": "HYPERTENSION",
      "count": 188
    },
    {
      "term": "INSOMNIA",
      "count": 187
    },
    {
      "term": "ERYTHEMA",
      "count": 184
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 181
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 175
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 170
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 168
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 167
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 166
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 165
    },
    {
      "term": "PANCYTOPENIA",
      "count": 161
    },
    {
      "term": "BACK PAIN",
      "count": 160
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 160
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 160
    },
    {
      "term": "COVID-19",
      "count": 159
    },
    {
      "term": "LEUKOPENIA",
      "count": 159
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 159
    },
    {
      "term": "HYPOTENSION",
      "count": 158
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 157
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 148
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 142
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 139
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 138
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 137
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 136
    },
    {
      "term": "CHILLS",
      "count": 135
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 132
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 129
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 125
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 125
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 124
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 122
    },
    {
      "term": "EYE PAIN",
      "count": 121
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 121
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 120
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 120
    },
    {
      "term": "DEHYDRATION",
      "count": 118
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 118
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 117
    },
    {
      "term": "ANXIETY",
      "count": 115
    },
    {
      "term": "RENAL FAILURE",
      "count": 115
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 114
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 114
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 112
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 112
    },
    {
      "term": "FALL",
      "count": 111
    },
    {
      "term": "HYPOALBUMINAEMIA",
      "count": 111
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 111
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 110
    },
    {
      "term": "CHEST PAIN",
      "count": 110
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 110
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 110
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 109
    },
    {
      "term": "TACHYCARDIA",
      "count": 107
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 106
    },
    {
      "term": "SEIZURE",
      "count": 106
    }
  ]
}