{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 23274
    },
    {
      "term": "FATIGUE",
      "count": 18258
    },
    {
      "term": "DIARRHOEA",
      "count": 18185
    },
    {
      "term": "NAUSEA",
      "count": 15163
    },
    {
      "term": "PNEUMONIA",
      "count": 14958
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 14406
    },
    {
      "term": "DEATH",
      "count": 13876
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 13747
    },
    {
      "term": "NEUTROPENIA",
      "count": 12484
    },
    {
      "term": "PYREXIA",
      "count": 12253
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 11399
    },
    {
      "term": "DYSPNOEA",
      "count": 11302
    },
    {
      "term": "ANAEMIA",
      "count": 10015
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 9783
    },
    {
      "term": "VOMITING",
      "count": 9707
    },
    {
      "term": "ASTHENIA",
      "count": 9530
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 9159
    },
    {
      "term": "RASH",
      "count": 8992
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 8077
    },
    {
      "term": "CONSTIPATION",
      "count": 7457
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 6763
    },
    {
      "term": "SEPSIS",
      "count": 6710
    },
    {
      "term": "DECREASED APPETITE",
      "count": 6652
    },
    {
      "term": "HEADACHE",
      "count": 6282
    },
    {
      "term": "PAIN",
      "count": 6223
    },
    {
      "term": "DIZZINESS",
      "count": 6049
    },
    {
      "term": "INFECTION",
      "count": 5742
    },
    {
      "term": "HYPOTENSION",
      "count": 5501
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 5442
    },
    {
      "term": "MALAISE",
      "count": 5319
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 5089
    },
    {
      "term": "BACK PAIN",
      "count": 5073
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 4869
    },
    {
      "term": "PANCYTOPENIA",
      "count": 4823
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 4809
    },
    {
      "term": "FALL",
      "count": 4713
    },
    {
      "term": "COUGH",
      "count": 4510
    },
    {
      "term": "COVID-19",
      "count": 4449
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 4379
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 4377
    },
    {
      "term": "DEHYDRATION",
      "count": 4350
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 4242
    },
    {
      "term": "PRURITUS",
      "count": 4212
    },
    {
      "term": "ARTHRALGIA",
      "count": 4068
    },
    {
      "term": "INSOMNIA",
      "count": 3988
    },
    {
      "term": "HYPERTENSION",
      "count": 3939
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 3892
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 3846
    },
    {
      "term": "ALOPECIA",
      "count": 3781
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 3739
    },
    {
      "term": "RENAL FAILURE",
      "count": 3720
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 3706
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 3705
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 3690
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 3636
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 3558
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 3486
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 3446
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 3434
    },
    {
      "term": "LEUKOPENIA",
      "count": 3416
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 3359
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 3353
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 3343
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 3299
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 3276
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 3154
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 3093
    },
    {
      "term": "CHEST PAIN",
      "count": 3034
    },
    {
      "term": "ERYTHEMA",
      "count": 2955
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 2955
    },
    {
      "term": "ANXIETY",
      "count": 2910
    },
    {
      "term": "THROMBOSIS",
      "count": 2867
    },
    {
      "term": "PARAESTHESIA",
      "count": 2855
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 2702
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 2661
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 2614
    },
    {
      "term": "STOMATITIS",
      "count": 2595
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 2590
    },
    {
      "term": "TREMOR",
      "count": 2576
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 2569
    },
    {
      "term": "CHILLS",
      "count": 2550
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 2549
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 2525
    },
    {
      "term": "DRUG INTERACTION",
      "count": 2513
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 2437
    },
    {
      "term": "TACHYCARDIA",
      "count": 2412
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 2391
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 2340
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 2339
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 2308
    },
    {
      "term": "SOMNOLENCE",
      "count": 2273
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 2176
    },
    {
      "term": "SYNCOPE",
      "count": 2150
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 2086
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 2073
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 2071
    },
    {
      "term": "INFLUENZA",
      "count": 2064
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 2058
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 2027
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 2026
    }
  ]
}