{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 554
    },
    {
      "term": "OFF LABEL USE",
      "count": 502
    },
    {
      "term": "DEATH",
      "count": 429
    },
    {
      "term": "PNEUMONIA",
      "count": 427
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 403
    },
    {
      "term": "NEUTROPENIA",
      "count": 371
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 364
    },
    {
      "term": "PYREXIA",
      "count": 353
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 338
    },
    {
      "term": "FATIGUE",
      "count": 322
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 300
    },
    {
      "term": "NAUSEA",
      "count": 278
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 278
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 277
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 269
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 242
    },
    {
      "term": "INFECTION",
      "count": 241
    },
    {
      "term": "SEPSIS",
      "count": 237
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 233
    },
    {
      "term": "DIARRHOEA",
      "count": 216
    },
    {
      "term": "ASTHENIA",
      "count": 212
    },
    {
      "term": "ANAEMIA",
      "count": 205
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 202
    },
    {
      "term": "PANCYTOPENIA",
      "count": 194
    },
    {
      "term": "TRANSFUSION",
      "count": 194
    },
    {
      "term": "FULL BLOOD COUNT ABNORMAL",
      "count": 180
    },
    {
      "term": "DYSPNOEA",
      "count": 178
    },
    {
      "term": "CONSTIPATION",
      "count": 141
    },
    {
      "term": "VOMITING",
      "count": 141
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 140
    },
    {
      "term": "THERAPY INTERRUPTED",
      "count": 139
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 135
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 127
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 127
    },
    {
      "term": "DECREASED APPETITE",
      "count": 112
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 111
    },
    {
      "term": "HYPOTENSION",
      "count": 108
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 101
    },
    {
      "term": "DIZZINESS",
      "count": 100
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 99
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 92
    },
    {
      "term": "CYTOPENIA",
      "count": 86
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 85
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 84
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 82
    },
    {
      "term": "FALL",
      "count": 81
    },
    {
      "term": "HEADACHE",
      "count": 80
    },
    {
      "term": "BACTERAEMIA",
      "count": 78
    },
    {
      "term": "COVID-19",
      "count": 77
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 76
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 76
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 75
    },
    {
      "term": "MALAISE",
      "count": 74
    },
    {
      "term": "PAIN",
      "count": 73
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 71
    },
    {
      "term": "COUGH",
      "count": 70
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 67
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 67
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 67
    },
    {
      "term": "RASH",
      "count": 65
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 63
    },
    {
      "term": "CHILLS",
      "count": 62
    },
    {
      "term": "EASTERN COOPERATIVE ONCOLOGY GROUP PERFORMANCE STATUS WORSENED",
      "count": 62
    },
    {
      "term": "PLATELET TRANSFUSION",
      "count": 62
    },
    {
      "term": "CELLULITIS",
      "count": 60
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 60
    },
    {
      "term": "LUNG INFECTION",
      "count": 60
    },
    {
      "term": "ARTHRALGIA",
      "count": 59
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 58
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 55
    },
    {
      "term": "BIOPSY BONE MARROW",
      "count": 53
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 53
    },
    {
      "term": "EPISTAXIS",
      "count": 52
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 52
    },
    {
      "term": "HYPOXIA",
      "count": 51
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 50
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 48
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 48
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 48
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 48
    },
    {
      "term": "BLOOD PRODUCT TRANSFUSION DEPENDENT",
      "count": 47
    },
    {
      "term": "LEUKOPENIA",
      "count": 47
    },
    {
      "term": "STOMATITIS",
      "count": 47
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 46
    },
    {
      "term": "BACK PAIN",
      "count": 45
    },
    {
      "term": "HAEMORRHAGE",
      "count": 45
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 45
    },
    {
      "term": "CHEST PAIN",
      "count": 44
    },
    {
      "term": "DEHYDRATION",
      "count": 44
    },
    {
      "term": "PNEUMONIA FUNGAL",
      "count": 44
    },
    {
      "term": "CARDIAC ARREST",
      "count": 43
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 42
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 42
    },
    {
      "term": "RENAL FAILURE",
      "count": 42
    },
    {
      "term": "COLITIS",
      "count": 41
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 40
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 40
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 39
    },
    {
      "term": "ILLNESS",
      "count": 39
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 39
    }
  ]
}