{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INTERACTION",
      "count": 988
    },
    {
      "term": "VIROLOGIC FAILURE",
      "count": 615
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 564
    },
    {
      "term": "OFF LABEL USE",
      "count": 496
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 454
    },
    {
      "term": "VIRAL MUTATION IDENTIFIED",
      "count": 402
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 386
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 365
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 353
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 309
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 305
    },
    {
      "term": "DEATH",
      "count": 289
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 276
    },
    {
      "term": "IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME",
      "count": 262
    },
    {
      "term": "DIARRHOEA",
      "count": 255
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 241
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 227
    },
    {
      "term": "NAUSEA",
      "count": 211
    },
    {
      "term": "PYREXIA",
      "count": 206
    },
    {
      "term": "PREMATURE BABY",
      "count": 195
    },
    {
      "term": "VOMITING",
      "count": 194
    },
    {
      "term": "BLOOD HIV RNA INCREASED",
      "count": 190
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 187
    },
    {
      "term": "ABORTION SPONTANEOUS",
      "count": 186
    },
    {
      "term": "CUSHING^S SYNDROME",
      "count": 174
    },
    {
      "term": "LIPODYSTROPHY ACQUIRED",
      "count": 157
    },
    {
      "term": "ANAEMIA",
      "count": 154
    },
    {
      "term": "RASH",
      "count": 151
    },
    {
      "term": "HEADACHE",
      "count": 145
    },
    {
      "term": "FATIGUE",
      "count": 142
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 139
    },
    {
      "term": "OSTEOPOROSIS",
      "count": 127
    },
    {
      "term": "ASTHENIA",
      "count": 123
    },
    {
      "term": "CD4 LYMPHOCYTES DECREASED",
      "count": 117
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 117
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 110
    },
    {
      "term": "DEPRESSION",
      "count": 109
    },
    {
      "term": "MALAISE",
      "count": 108
    },
    {
      "term": "EYELID PTOSIS",
      "count": 106
    },
    {
      "term": "MITOCHONDRIAL TOXICITY",
      "count": 105
    },
    {
      "term": "PNEUMONIA",
      "count": 105
    },
    {
      "term": "DIPLOPIA",
      "count": 104
    },
    {
      "term": "ANXIETY",
      "count": 99
    },
    {
      "term": "PAIN",
      "count": 99
    },
    {
      "term": "LOW BIRTH WEIGHT BABY",
      "count": 98
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 97
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 96
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 92
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 92
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 91
    },
    {
      "term": "HYPERTENSION",
      "count": 91
    },
    {
      "term": "PANCYTOPENIA",
      "count": 91
    },
    {
      "term": "VIRAL LOAD INCREASED",
      "count": 90
    },
    {
      "term": "MYALGIA",
      "count": 87
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 86
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 85
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 85
    },
    {
      "term": "DYSLIPIDAEMIA",
      "count": 85
    },
    {
      "term": "DYSPNOEA",
      "count": 85
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 85
    },
    {
      "term": "LIVE BIRTH",
      "count": 84
    },
    {
      "term": "RENAL FAILURE",
      "count": 84
    },
    {
      "term": "PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA",
      "count": 82
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 81
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 79
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 78
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 77
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 77
    },
    {
      "term": "NEUTROPENIA",
      "count": 73
    },
    {
      "term": "HYPOTENSION",
      "count": 72
    },
    {
      "term": "CD4/CD8 RATIO DECREASED",
      "count": 71
    },
    {
      "term": "GENOTYPE DRUG RESISTANCE TEST POSITIVE",
      "count": 71
    },
    {
      "term": "INSOMNIA",
      "count": 71
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 69
    },
    {
      "term": "ARTHRALGIA",
      "count": 68
    },
    {
      "term": "DECREASED APPETITE",
      "count": 68
    },
    {
      "term": "OSTEONECROSIS",
      "count": 66
    },
    {
      "term": "SEPSIS",
      "count": 66
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 65
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 65
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 64
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 62
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 60
    },
    {
      "term": "DIZZINESS",
      "count": 58
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 58
    },
    {
      "term": "ABORTION INDUCED",
      "count": 57
    },
    {
      "term": "DRUG EXPOSURE DURING PREGNANCY",
      "count": 57
    },
    {
      "term": "CHEST PAIN",
      "count": 56
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 56
    },
    {
      "term": "CARDIAC ARREST",
      "count": 55
    },
    {
      "term": "KAPOSI^S SARCOMA",
      "count": 55
    },
    {
      "term": "COVID-19",
      "count": 54
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 54
    },
    {
      "term": "DYSPHAGIA",
      "count": 53
    },
    {
      "term": "HEPATITIS C",
      "count": 53
    },
    {
      "term": "OVERDOSE",
      "count": 53
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 52
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 52
    },
    {
      "term": "PANCREATITIS",
      "count": 52
    },
    {
      "term": "ERYTHEMA",
      "count": 51
    }
  ]
}