{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 731
    },
    {
      "term": "OFF LABEL USE",
      "count": 682
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 576
    },
    {
      "term": "PYREXIA",
      "count": 503
    },
    {
      "term": "EOSINOPHILIC PNEUMONIA",
      "count": 478
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 380
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 371
    },
    {
      "term": "EOSINOPHILIA",
      "count": 364
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 331
    },
    {
      "term": "CHILLS",
      "count": 300
    },
    {
      "term": "NEUTROPENIA",
      "count": 288
    },
    {
      "term": "RASH",
      "count": 284
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 280
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 269
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 253
    },
    {
      "term": "PNEUMONITIS",
      "count": 251
    },
    {
      "term": "DYSPNOEA",
      "count": 239
    },
    {
      "term": "DRUG INTERACTION",
      "count": 226
    },
    {
      "term": "SEPSIS",
      "count": 217
    },
    {
      "term": "PNEUMONIA",
      "count": 215
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 208
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 197
    },
    {
      "term": "NAUSEA",
      "count": 189
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 178
    },
    {
      "term": "DEATH",
      "count": 169
    },
    {
      "term": "CHOLESTASIS",
      "count": 165
    },
    {
      "term": "TREMOR",
      "count": 164
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 163
    },
    {
      "term": "LEUKOPENIA",
      "count": 152
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 151
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 151
    },
    {
      "term": "EOSINOPHILIC PNEUMONIA ACUTE",
      "count": 149
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 149
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 145
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 140
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 140
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 137
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 137
    },
    {
      "term": "HYPOTENSION",
      "count": 134
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 134
    },
    {
      "term": "PANCYTOPENIA",
      "count": 132
    },
    {
      "term": "DIARRHOEA",
      "count": 127
    },
    {
      "term": "ANAEMIA",
      "count": 125
    },
    {
      "term": "RENAL FAILURE",
      "count": 123
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 122
    },
    {
      "term": "BACTERAEMIA",
      "count": 121
    },
    {
      "term": "MALAISE",
      "count": 117
    },
    {
      "term": "PRURITUS",
      "count": 117
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 116
    },
    {
      "term": "FATIGUE",
      "count": 115
    },
    {
      "term": "LUNG DISORDER",
      "count": 115
    },
    {
      "term": "ASTHENIA",
      "count": 114
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 114
    },
    {
      "term": "STAPHYLOCOCCAL BACTERAEMIA",
      "count": 112
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 107
    },
    {
      "term": "MYALGIA",
      "count": 104
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 103
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 99
    },
    {
      "term": "VOMITING",
      "count": 99
    },
    {
      "term": "INFECTION",
      "count": 95
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 94
    },
    {
      "term": "ERYTHEMA",
      "count": 94
    },
    {
      "term": "PAIN",
      "count": 91
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 86
    },
    {
      "term": "URTICARIA",
      "count": 81
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 80
    },
    {
      "term": "LOWER RESPIRATORY TRACT INFECTION",
      "count": 73
    },
    {
      "term": "ARTHRALGIA",
      "count": 72
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 71
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 71
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 70
    },
    {
      "term": "OSTEOMYELITIS",
      "count": 70
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 70
    },
    {
      "term": "TACHYCARDIA",
      "count": 69
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 68
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 68
    },
    {
      "term": "COUGH",
      "count": 67
    },
    {
      "term": "HYPOXIA",
      "count": 67
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 66
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 66
    },
    {
      "term": "HEADACHE",
      "count": 65
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 65
    },
    {
      "term": "CHEST PAIN",
      "count": 63
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 63
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 61
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 60
    },
    {
      "term": "DIZZINESS",
      "count": 60
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 59
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 59
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 58
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 58
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 57
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 56
    },
    {
      "term": "BACK PAIN",
      "count": 55
    },
    {
      "term": "CARDIAC ARREST",
      "count": 55
    },
    {
      "term": "DRUG ERUPTION",
      "count": 55
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 55
    },
    {
      "term": "SYSTEMIC CANDIDA",
      "count": 55
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 54
    },
    {
      "term": "CELLULITIS",
      "count": 53
    }
  ]
}