{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 71
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 39
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 36
    },
    {
      "term": "PYREXIA",
      "count": 33
    },
    {
      "term": "VOMITING",
      "count": 30
    },
    {
      "term": "ERYTHEMA",
      "count": 19
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 19
    },
    {
      "term": "DECREASED APPETITE",
      "count": 18
    },
    {
      "term": "DIARRHOEA",
      "count": 18
    },
    {
      "term": "MALAISE",
      "count": 18
    },
    {
      "term": "NEUTROPENIA",
      "count": 16
    },
    {
      "term": "DYSPNOEA",
      "count": 15
    },
    {
      "term": "PRURITUS",
      "count": 15
    },
    {
      "term": "RASH",
      "count": 15
    },
    {
      "term": "CHILLS",
      "count": 14
    },
    {
      "term": "NAUSEA",
      "count": 14
    },
    {
      "term": "DEATH",
      "count": 13
    },
    {
      "term": "HYPERTENSION",
      "count": 13
    },
    {
      "term": "BACK PAIN",
      "count": 12
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 12
    },
    {
      "term": "TREMOR",
      "count": 12
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 11
    },
    {
      "term": "CELLULITIS",
      "count": 10
    },
    {
      "term": "PALLOR",
      "count": 10
    },
    {
      "term": "TACHYCARDIA",
      "count": 10
    },
    {
      "term": "CHOLESTASIS",
      "count": 9
    },
    {
      "term": "HYPOTENSION",
      "count": 9
    },
    {
      "term": "PRESYNCOPE",
      "count": 9
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 9
    },
    {
      "term": "SEIZURE",
      "count": 9
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 9
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 9
    },
    {
      "term": "AUTONOMIC NERVOUS SYSTEM IMBALANCE",
      "count": 8
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 8
    },
    {
      "term": "EOSINOPHILIA",
      "count": 8
    },
    {
      "term": "RENAL FAILURE",
      "count": 8
    },
    {
      "term": "SUDDEN DEATH",
      "count": 8
    },
    {
      "term": "CHEST PAIN",
      "count": 7
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 7
    },
    {
      "term": "HEPATOCELLULAR INJURY",
      "count": 7
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 7
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 7
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 7
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 7
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 6
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 6
    },
    {
      "term": "CARDIAC ARREST",
      "count": 6
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 6
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 6
    },
    {
      "term": "DIZZINESS",
      "count": 6
    },
    {
      "term": "ENDOCARDITIS",
      "count": 6
    },
    {
      "term": "FLUSHING",
      "count": 6
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 6
    },
    {
      "term": "SEPSIS",
      "count": 6
    },
    {
      "term": "THERAPEUTIC PRODUCT CROSS-REACTIVITY",
      "count": 6
    },
    {
      "term": "URTICARIA",
      "count": 6
    },
    {
      "term": "ABSCESS LIMB",
      "count": 5
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 5
    },
    {
      "term": "ANAEMIA",
      "count": 5
    },
    {
      "term": "BACTERAEMIA",
      "count": 5
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 5
    },
    {
      "term": "DEAFNESS NEUROSENSORY",
      "count": 5
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 5
    },
    {
      "term": "LEUKOPENIA",
      "count": 5
    },
    {
      "term": "MIXED LIVER INJURY",
      "count": 5
    },
    {
      "term": "PAIN",
      "count": 5
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 5
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 5
    },
    {
      "term": "ARTHRALGIA",
      "count": 4
    },
    {
      "term": "ARTHRITIS INFECTIVE",
      "count": 4
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 4
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 4
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 4
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 4
    },
    {
      "term": "HYPOXIA",
      "count": 4
    },
    {
      "term": "INFECTION",
      "count": 4
    },
    {
      "term": "INFLAMMATION",
      "count": 4
    },
    {
      "term": "MULTIPLE-DRUG RESISTANCE",
      "count": 4
    },
    {
      "term": "PELVIC HAEMORRHAGE",
      "count": 4
    },
    {
      "term": "PRODUCT PREPARATION ISSUE",
      "count": 4
    },
    {
      "term": "RASH PRURITIC",
      "count": 4
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 4
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 4
    },
    {
      "term": "VANCOMYCIN INFUSION REACTION",
      "count": 4
    },
    {
      "term": "ADMINISTRATION SITE EXTRAVASATION",
      "count": 3
    },
    {
      "term": "ADVERSE DRUG REACTION",
      "count": 3
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 3
    },
    {
      "term": "ANAPHYLACTOID REACTION",
      "count": 3
    },
    {
      "term": "ANGIOEDEMA",
      "count": 3
    },
    {
      "term": "BICYTOPENIA",
      "count": 3
    },
    {
      "term": "COLD SWEAT",
      "count": 3
    },
    {
      "term": "DEBRIDEMENT",
      "count": 3
    },
    {
      "term": "DEVICE RELATED INFECTION",
      "count": 3
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 3
    },
    {
      "term": "FATIGUE",
      "count": 3
    },
    {
      "term": "HAEMATURIA",
      "count": 3
    },
    {
      "term": "HEAD AND NECK CANCER",
      "count": 3
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 3
    },
    {
      "term": "HEPATITIS",
      "count": 3
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 3
    }
  ]
}