{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 7946
    },
    {
      "term": "OFF LABEL USE",
      "count": 5358
    },
    {
      "term": "PYREXIA",
      "count": 4307
    },
    {
      "term": "NEUTROPENIA",
      "count": 3829
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3208
    },
    {
      "term": "SEPSIS",
      "count": 3069
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 3042
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 2804
    },
    {
      "term": "PNEUMONIA",
      "count": 2427
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 2219
    },
    {
      "term": "PANCYTOPENIA",
      "count": 2207
    },
    {
      "term": "DEATH",
      "count": 2085
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 1964
    },
    {
      "term": "NAUSEA",
      "count": 1903
    },
    {
      "term": "ANAEMIA",
      "count": 1884
    },
    {
      "term": "INFECTION",
      "count": 1880
    },
    {
      "term": "DIARRHOEA",
      "count": 1876
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 1848
    },
    {
      "term": "VOMITING",
      "count": 1805
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1785
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1719
    },
    {
      "term": "HYPOTENSION",
      "count": 1529
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 1372
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 1359
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1312
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 1303
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 1300
    },
    {
      "term": "HEADACHE",
      "count": 1098
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1052
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 1000
    },
    {
      "term": "DYSPNOEA",
      "count": 986
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 936
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 923
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 910
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 907
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 869
    },
    {
      "term": "RENAL FAILURE",
      "count": 869
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 862
    },
    {
      "term": "RASH",
      "count": 861
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 833
    },
    {
      "term": "TACHYCARDIA",
      "count": 825
    },
    {
      "term": "ASTHENIA",
      "count": 821
    },
    {
      "term": "STOMATITIS",
      "count": 804
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 796
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 794
    },
    {
      "term": "COLITIS",
      "count": 786
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 786
    },
    {
      "term": "FATIGUE",
      "count": 784
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 770
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 769
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 768
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 762
    },
    {
      "term": "NEUROTOXICITY",
      "count": 750
    },
    {
      "term": "LEUKOPENIA",
      "count": 738
    },
    {
      "term": "DRUG INTERACTION",
      "count": 710
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 668
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 662
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 651
    },
    {
      "term": "CHILLS",
      "count": 649
    },
    {
      "term": "BACTERAEMIA",
      "count": 643
    },
    {
      "term": "HYPOXIA",
      "count": 624
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 621
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 618
    },
    {
      "term": "COVID-19",
      "count": 615
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 614
    },
    {
      "term": "COUGH",
      "count": 605
    },
    {
      "term": "DECREASED APPETITE",
      "count": 603
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 592
    },
    {
      "term": "HYPERTENSION",
      "count": 584
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 579
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 578
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 575
    },
    {
      "term": "CYTOPENIA",
      "count": 552
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 550
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 548
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 547
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 544
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 527
    },
    {
      "term": "POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME",
      "count": 527
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 525
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 517
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 517
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 513
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 513
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 505
    },
    {
      "term": "CARDIAC ARREST",
      "count": 503
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 496
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 491
    },
    {
      "term": "SEIZURE",
      "count": 491
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 487
    },
    {
      "term": "CELLULITIS",
      "count": 485
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 485
    },
    {
      "term": "PAIN",
      "count": 481
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA RECURRENT",
      "count": 480
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 479
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 473
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 452
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 434
    },
    {
      "term": "BLOOD CULTURE POSITIVE",
      "count": 433
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 432
    }
  ]
}