{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 332
    },
    {
      "term": "OFF LABEL USE",
      "count": 237
    },
    {
      "term": "PYREXIA",
      "count": 230
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 198
    },
    {
      "term": "SEPSIS",
      "count": 192
    },
    {
      "term": "NEUTROPENIA",
      "count": 154
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 143
    },
    {
      "term": "HYPOTENSION",
      "count": 140
    },
    {
      "term": "PANCYTOPENIA",
      "count": 135
    },
    {
      "term": "NAUSEA",
      "count": 133
    },
    {
      "term": "VOMITING",
      "count": 128
    },
    {
      "term": "PNEUMONIA",
      "count": 119
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 116
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 111
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 110
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 109
    },
    {
      "term": "DEATH",
      "count": 108
    },
    {
      "term": "DIARRHOEA",
      "count": 108
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 106
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 100
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 97
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 96
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 93
    },
    {
      "term": "RENAL FAILURE",
      "count": 92
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 89
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 87
    },
    {
      "term": "OEDEMA",
      "count": 84
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 83
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 82
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 81
    },
    {
      "term": "DYSPNOEA",
      "count": 81
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 79
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 77
    },
    {
      "term": "INFECTION",
      "count": 74
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 74
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 71
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 66
    },
    {
      "term": "CAPILLARY LEAK SYNDROME",
      "count": 65
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 64
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 63
    },
    {
      "term": "RASH",
      "count": 63
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 56
    },
    {
      "term": "ANAEMIA",
      "count": 55
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 54
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 53
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 51
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 48
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 48
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 47
    },
    {
      "term": "TACHYCARDIA",
      "count": 46
    },
    {
      "term": "APLASIA",
      "count": 45
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 45
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 45
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 45
    },
    {
      "term": "ADENOVIRUS INFECTION",
      "count": 44
    },
    {
      "term": "DECREASED APPETITE",
      "count": 44
    },
    {
      "term": "BLOOD CULTURE POSITIVE",
      "count": 43
    },
    {
      "term": "CARDIAC ARREST",
      "count": 42
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 42
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 42
    },
    {
      "term": "HEADACHE",
      "count": 42
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 42
    },
    {
      "term": "SKIN TOXICITY",
      "count": 42
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 41
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 40
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 40
    },
    {
      "term": "HYPOXIA",
      "count": 40
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 39
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 39
    },
    {
      "term": "RESPIRATORY DISTRESS",
      "count": 39
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 39
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 38
    },
    {
      "term": "VENOOCCLUSIVE DISEASE",
      "count": 38
    },
    {
      "term": "CYSTITIS HAEMORRHAGIC",
      "count": 37
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 37
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 36
    },
    {
      "term": "STOMATITIS",
      "count": 36
    },
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA RECURRENT",
      "count": 35
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 35
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 35
    },
    {
      "term": "ASCITES",
      "count": 34
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 34
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 34
    },
    {
      "term": "PNEUMONIA FUNGAL",
      "count": 34
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 34
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 33
    },
    {
      "term": "ASTHENIA",
      "count": 33
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 33
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 32
    },
    {
      "term": "ERYTHEMA",
      "count": 32
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 32
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 31
    },
    {
      "term": "HYPERTENSION",
      "count": 31
    },
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA",
      "count": 30
    },
    {
      "term": "PAIN",
      "count": 30
    },
    {
      "term": "BACTERIAL SEPSIS",
      "count": 29
    },
    {
      "term": "DIALYSIS",
      "count": 29
    },
    {
      "term": "HYPOGAMMAGLOBULINAEMIA",
      "count": 29
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 29
    },
    {
      "term": "COLITIS",
      "count": 28
    }
  ]
}