{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 96
    },
    {
      "term": "NAUSEA",
      "count": 87
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 84
    },
    {
      "term": "PYREXIA",
      "count": 75
    },
    {
      "term": "MACULAR DEGENERATION",
      "count": 72
    },
    {
      "term": "ANAEMIA",
      "count": 71
    },
    {
      "term": "HEADACHE",
      "count": 71
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 70
    },
    {
      "term": "CONSTIPATION",
      "count": 69
    },
    {
      "term": "PAIN",
      "count": 69
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 68
    },
    {
      "term": "MALAISE",
      "count": 66
    },
    {
      "term": "COLITIS",
      "count": 65
    },
    {
      "term": "ERYTHEMA",
      "count": 65
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 64
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 64
    },
    {
      "term": "PARAESTHESIA ORAL",
      "count": 64
    },
    {
      "term": "RADICULOPATHY",
      "count": 64
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 64
    },
    {
      "term": "CHRONIC SINUSITIS",
      "count": 63
    },
    {
      "term": "FEMALE GENITAL TRACT FISTULA",
      "count": 63
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 63
    },
    {
      "term": "PROCTITIS",
      "count": 63
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 63
    },
    {
      "term": "VAGINAL DISCHARGE",
      "count": 63
    },
    {
      "term": "VAGINAL FLATULENCE",
      "count": 63
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 62
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 62
    },
    {
      "term": "PROCEDURAL PAIN",
      "count": 60
    },
    {
      "term": "DYSPEPSIA",
      "count": 59
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 25
    },
    {
      "term": "DIARRHOEA",
      "count": 20
    },
    {
      "term": "VOMITING",
      "count": 20
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 19
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 17
    },
    {
      "term": "FATIGUE",
      "count": 17
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 16
    },
    {
      "term": "PRURITUS",
      "count": 16
    },
    {
      "term": "PRODUCT PRESCRIBING ERROR",
      "count": 14
    },
    {
      "term": "DRUG INTERACTION",
      "count": 13
    },
    {
      "term": "HYPOTENSION",
      "count": 12
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 11
    },
    {
      "term": "BLISTER",
      "count": 10
    },
    {
      "term": "DYSPNOEA",
      "count": 10
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 9
    },
    {
      "term": "EPISTAXIS",
      "count": 9
    },
    {
      "term": "FALL",
      "count": 9
    },
    {
      "term": "HOSPITALISATION",
      "count": 9
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 9
    },
    {
      "term": "NIKOLSKY^S SIGN",
      "count": 9
    },
    {
      "term": "SEIZURE",
      "count": 9
    },
    {
      "term": "VASCULAR DEVICE INFECTION",
      "count": 9
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 8
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 8
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 7
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 7
    },
    {
      "term": "RESTLESSNESS",
      "count": 7
    },
    {
      "term": "ANGINA PECTORIS",
      "count": 6
    },
    {
      "term": "BRAIN OEDEMA",
      "count": 6
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 6
    },
    {
      "term": "COVID-19",
      "count": 6
    },
    {
      "term": "DEATH",
      "count": 6
    },
    {
      "term": "PSEUDOMONAL SEPSIS",
      "count": 6
    },
    {
      "term": "STREPTOCOCCAL SEPSIS",
      "count": 6
    },
    {
      "term": "SYNCOPE",
      "count": 6
    },
    {
      "term": "UNDERDOSE",
      "count": 6
    },
    {
      "term": "VERTIGO",
      "count": 6
    },
    {
      "term": "BLINDNESS",
      "count": 5
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 5
    },
    {
      "term": "COUGH",
      "count": 5
    },
    {
      "term": "DIZZINESS",
      "count": 5
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 5
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 5
    },
    {
      "term": "PARONYCHIA",
      "count": 5
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 5
    },
    {
      "term": "SEPSIS",
      "count": 5
    },
    {
      "term": "SKIN FISSURES",
      "count": 5
    },
    {
      "term": "VARICOSE VEIN",
      "count": 5
    },
    {
      "term": "ASTHENIA",
      "count": 4
    },
    {
      "term": "BACK PAIN",
      "count": 4
    },
    {
      "term": "BALANCE DISORDER",
      "count": 4
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 4
    },
    {
      "term": "CARDIAC ARREST",
      "count": 4
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 4
    },
    {
      "term": "CARDIOMYOPATHY",
      "count": 4
    },
    {
      "term": "CHILLS",
      "count": 4
    },
    {
      "term": "DECREASED APPETITE",
      "count": 4
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 4
    },
    {
      "term": "DRUG ABUSE",
      "count": 4
    },
    {
      "term": "DYSPNOEA EXERTIONAL",
      "count": 4
    },
    {
      "term": "ECZEMA",
      "count": 4
    },
    {
      "term": "ENTERITIS",
      "count": 4
    },
    {
      "term": "HAEMODYNAMIC INSTABILITY",
      "count": 4
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 4
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 4
    },
    {
      "term": "INFECTION",
      "count": 4
    },
    {
      "term": "LYMPHOEDEMA",
      "count": 4
    },
    {
      "term": "METASTASES TO CENTRAL NERVOUS SYSTEM",
      "count": 4
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 4
    },
    {
      "term": "MYALGIA",
      "count": 4
    }
  ]
}