{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 377
    },
    {
      "term": "NAUSEA",
      "count": 289
    },
    {
      "term": "CONSTIPATION",
      "count": 257
    },
    {
      "term": "ANAEMIA",
      "count": 244
    },
    {
      "term": "PAIN",
      "count": 231
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 227
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 220
    },
    {
      "term": "PYREXIA",
      "count": 208
    },
    {
      "term": "HEADACHE",
      "count": 192
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 191
    },
    {
      "term": "VOMITING",
      "count": 177
    },
    {
      "term": "DYSPNOEA",
      "count": 176
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 146
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 143
    },
    {
      "term": "SEPSIS",
      "count": 142
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 139
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 138
    },
    {
      "term": "DIARRHOEA",
      "count": 137
    },
    {
      "term": "MALAISE",
      "count": 134
    },
    {
      "term": "FATIGUE",
      "count": 127
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 125
    },
    {
      "term": "STRESS",
      "count": 116
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 115
    },
    {
      "term": "SOMNOLENCE",
      "count": 114
    },
    {
      "term": "MACULAR DEGENERATION",
      "count": 112
    },
    {
      "term": "ASTHENIA",
      "count": 110
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 110
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 105
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 105
    },
    {
      "term": "COLITIS",
      "count": 104
    },
    {
      "term": "ERYTHEMA",
      "count": 104
    },
    {
      "term": "DYSPEPSIA",
      "count": 102
    },
    {
      "term": "RECTAL HAEMORRHAGE",
      "count": 101
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 100
    },
    {
      "term": "PARAESTHESIA ORAL",
      "count": 99
    },
    {
      "term": "COLITIS ULCERATIVE",
      "count": 98
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 98
    },
    {
      "term": "CHRONIC SINUSITIS",
      "count": 97
    },
    {
      "term": "VAGINAL DISCHARGE",
      "count": 97
    },
    {
      "term": "ASCITES",
      "count": 96
    },
    {
      "term": "FREQUENT BOWEL MOVEMENTS",
      "count": 96
    },
    {
      "term": "PROCTITIS",
      "count": 96
    },
    {
      "term": "RADICULOPATHY",
      "count": 96
    },
    {
      "term": "THROMBOSIS",
      "count": 96
    },
    {
      "term": "FEMALE GENITAL TRACT FISTULA",
      "count": 95
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 95
    },
    {
      "term": "VAGINAL FLATULENCE",
      "count": 95
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 94
    },
    {
      "term": "SWELLING",
      "count": 92
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 91
    },
    {
      "term": "PROCEDURAL PAIN",
      "count": 91
    },
    {
      "term": "FALL",
      "count": 90
    },
    {
      "term": "APPENDICITIS",
      "count": 89
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 89
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 88
    },
    {
      "term": "NEURALGIA",
      "count": 88
    },
    {
      "term": "APPENDICOLITH",
      "count": 87
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 87
    },
    {
      "term": "HYPERTENSION",
      "count": 87
    },
    {
      "term": "MYASTHENIA GRAVIS",
      "count": 86
    },
    {
      "term": "SLEEP DISORDER",
      "count": 85
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 84
    },
    {
      "term": "HYPERPHOSPHATAEMIA",
      "count": 80
    },
    {
      "term": "INCORRECT ROUTE OF PRODUCT ADMINISTRATION",
      "count": 80
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 80
    },
    {
      "term": "DEATH",
      "count": 79
    },
    {
      "term": "HYPOPHOSPHATAEMIA",
      "count": 79
    },
    {
      "term": "DRUG INTERACTION",
      "count": 78
    },
    {
      "term": "HYPOTENSION",
      "count": 77
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 74
    },
    {
      "term": "DRY MOUTH",
      "count": 73
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 71
    },
    {
      "term": "ACTIVATED PARTIAL THROMBOPLASTIN TIME PROLONGED",
      "count": 70
    },
    {
      "term": "PNEUMONIA",
      "count": 70
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 68
    },
    {
      "term": "BLOOD PHOSPHORUS INCREASED",
      "count": 65
    },
    {
      "term": "ANALGESIC THERAPY",
      "count": 64
    },
    {
      "term": "BLOOD CHOLESTEROL INCREASED",
      "count": 64
    },
    {
      "term": "SLEEP DISORDER THERAPY",
      "count": 64
    },
    {
      "term": "DRUG THERAPY",
      "count": 63
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 61
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 61
    },
    {
      "term": "ULCER",
      "count": 60
    },
    {
      "term": "BLOOD URIC ACID INCREASED",
      "count": 58
    },
    {
      "term": "COUGH",
      "count": 58
    },
    {
      "term": "GOUT",
      "count": 58
    },
    {
      "term": "MOBILITY DECREASED",
      "count": 58
    },
    {
      "term": "HYPERLIPIDAEMIA",
      "count": 57
    },
    {
      "term": "TROPONIN INCREASED",
      "count": 56
    },
    {
      "term": "TREMOR",
      "count": 55
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 54
    },
    {
      "term": "OVERDOSE",
      "count": 52
    },
    {
      "term": "BALANCE DISORDER",
      "count": 51
    },
    {
      "term": "ORTHOSTATIC HYPOTENSION",
      "count": 51
    },
    {
      "term": "ANTICOAGULANT THERAPY",
      "count": 50
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 50
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 50
    },
    {
      "term": "ANTACID THERAPY",
      "count": 49
    },
    {
      "term": "ASTHMA",
      "count": 49
    },
    {
      "term": "BLOOD CALCIUM DECREASED",
      "count": 49
    }
  ]
}