{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 5923
    },
    {
      "term": "NAUSEA",
      "count": 5594
    },
    {
      "term": "NEUTROPENIA",
      "count": 4995
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 4727
    },
    {
      "term": "VOMITING",
      "count": 4707
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 4682
    },
    {
      "term": "ANAEMIA",
      "count": 4080
    },
    {
      "term": "DIARRHOEA",
      "count": 3879
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 3864
    },
    {
      "term": "PYREXIA",
      "count": 3487
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 3284
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 3255
    },
    {
      "term": "DEATH",
      "count": 2757
    },
    {
      "term": "FATIGUE",
      "count": 2561
    },
    {
      "term": "DEHYDRATION",
      "count": 2542
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 2488
    },
    {
      "term": "PNEUMONIA",
      "count": 2392
    },
    {
      "term": "SEPSIS",
      "count": 2114
    },
    {
      "term": "ASTHENIA",
      "count": 2099
    },
    {
      "term": "DYSPNOEA",
      "count": 2001
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 1979
    },
    {
      "term": "PANCYTOPENIA",
      "count": 1963
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 1932
    },
    {
      "term": "DECREASED APPETITE",
      "count": 1919
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 1750
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 1726
    },
    {
      "term": "LEUKOPENIA",
      "count": 1722
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 1625
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 1566
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 1557
    },
    {
      "term": "HYPOTENSION",
      "count": 1403
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 1373
    },
    {
      "term": "RENAL FAILURE",
      "count": 1337
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 1314
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 1288
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 1233
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 1205
    },
    {
      "term": "DYSPHAGIA",
      "count": 1194
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 1187
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 1181
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1176
    },
    {
      "term": "STOMATITIS",
      "count": 1166
    },
    {
      "term": "RASH",
      "count": 1159
    },
    {
      "term": "INFECTION",
      "count": 1136
    },
    {
      "term": "CONSTIPATION",
      "count": 1101
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 1087
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 1085
    },
    {
      "term": "PAIN",
      "count": 1056
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 1037
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 1033
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 1003
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 972
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 957
    },
    {
      "term": "DIZZINESS",
      "count": 918
    },
    {
      "term": "MALAISE",
      "count": 890
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 877
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 870
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 851
    },
    {
      "term": "HYPERTENSION",
      "count": 827
    },
    {
      "term": "HEADACHE",
      "count": 822
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 806
    },
    {
      "term": "COUGH",
      "count": 802
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 739
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 718
    },
    {
      "term": "HYPOMAGNESAEMIA",
      "count": 717
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 699
    },
    {
      "term": "CHEST PAIN",
      "count": 675
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 671
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 655
    },
    {
      "term": "PNEUMONITIS",
      "count": 643
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 634
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 628
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 627
    },
    {
      "term": "TACHYCARDIA",
      "count": 624
    },
    {
      "term": "SYNCOPE",
      "count": 616
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 611
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 603
    },
    {
      "term": "CHILLS",
      "count": 592
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 566
    },
    {
      "term": "ALOPECIA",
      "count": 562
    },
    {
      "term": "DRUG INTERACTION",
      "count": 548
    },
    {
      "term": "BACK PAIN",
      "count": 542
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 530
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 521
    },
    {
      "term": "PRURITUS",
      "count": 519
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 515
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 512
    },
    {
      "term": "OESOPHAGITIS",
      "count": 506
    },
    {
      "term": "COLITIS",
      "count": 499
    },
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 495
    },
    {
      "term": "ERYTHEMA",
      "count": 493
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 487
    },
    {
      "term": "COVID-19",
      "count": 486
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 485
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 477
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 453
    },
    {
      "term": "FALL",
      "count": 450
    },
    {
      "term": "CARDIAC ARREST",
      "count": 445
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 443
    },
    {
      "term": "ASCITES",
      "count": 441
    }
  ]
}