{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 129
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 81
    },
    {
      "term": "DEATH",
      "count": 70
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 44
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 39
    },
    {
      "term": "NEUTROPENIA",
      "count": 38
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 36
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 31
    },
    {
      "term": "PYREXIA",
      "count": 31
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 28
    },
    {
      "term": "RASH",
      "count": 26
    },
    {
      "term": "EOSINOPHILIA",
      "count": 25
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 22
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 22
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 21
    },
    {
      "term": "LEUKOPENIA",
      "count": 20
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 19
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 17
    },
    {
      "term": "HYPOPHAGIA",
      "count": 17
    },
    {
      "term": "ANAEMIA",
      "count": 15
    },
    {
      "term": "RENAL FAILURE",
      "count": 14
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 13
    },
    {
      "term": "DRUG INTERACTION",
      "count": 13
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 13
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 13
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 13
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 13
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 13
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 13
    },
    {
      "term": "BACTERAEMIA",
      "count": 12
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF DRUG ADMINISTRATION",
      "count": 12
    },
    {
      "term": "PRURITUS",
      "count": 12
    },
    {
      "term": "PANCYTOPENIA",
      "count": 11
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 11
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 10
    },
    {
      "term": "DYSPNOEA",
      "count": 10
    },
    {
      "term": "EOSINOPHILIC PNEUMONIA",
      "count": 10
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 10
    },
    {
      "term": "INTERNATIONAL NORMALISED RATIO INCREASED",
      "count": 10
    },
    {
      "term": "PNEUMONIA",
      "count": 10
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 10
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 9
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 9
    },
    {
      "term": "STAPHYLOCOCCAL BACTERAEMIA",
      "count": 9
    },
    {
      "term": "DIARRHOEA",
      "count": 8
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 8
    },
    {
      "term": "INFLAMMATORY MARKER INCREASED",
      "count": 8
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 8
    },
    {
      "term": "BACK PAIN",
      "count": 7
    },
    {
      "term": "ENDOCARDITIS",
      "count": 7
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 7
    },
    {
      "term": "HAEMARTHROSIS",
      "count": 7
    },
    {
      "term": "HEPATIC CYTOLYSIS",
      "count": 7
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 7
    },
    {
      "term": "HYPOTENSION",
      "count": 7
    },
    {
      "term": "INFECTION",
      "count": 7
    },
    {
      "term": "INTERVERTEBRAL DISCITIS",
      "count": 7
    },
    {
      "term": "NAUSEA",
      "count": 7
    },
    {
      "term": "RASH ERYTHEMATOUS",
      "count": 7
    },
    {
      "term": "VOMITING",
      "count": 7
    },
    {
      "term": "ARTERIOSCLEROSIS",
      "count": 6
    },
    {
      "term": "ASYMPTOMATIC BACTERIURIA",
      "count": 6
    },
    {
      "term": "ATROPHY",
      "count": 6
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 6
    },
    {
      "term": "CHILLS",
      "count": 6
    },
    {
      "term": "EOSINOPHILIC PNEUMONIA ACUTE",
      "count": 6
    },
    {
      "term": "FIBROSIS",
      "count": 6
    },
    {
      "term": "INCORRECT DRUG ADMINISTRATION DURATION",
      "count": 6
    },
    {
      "term": "MALAISE",
      "count": 6
    },
    {
      "term": "OSTEOMYELITIS",
      "count": 6
    },
    {
      "term": "OSTEONECROSIS",
      "count": 6
    },
    {
      "term": "SEPSIS",
      "count": 6
    },
    {
      "term": "SOMNOLENCE",
      "count": 6
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 6
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 6
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 5
    },
    {
      "term": "CARDIAC ARREST",
      "count": 5
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 5
    },
    {
      "term": "CHEST PAIN",
      "count": 5
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 5
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 5
    },
    {
      "term": "HAEMOLYSIS",
      "count": 5
    },
    {
      "term": "HAEMOLYTIC ANAEMIA",
      "count": 5
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 5
    },
    {
      "term": "NEUROTOXICITY",
      "count": 5
    },
    {
      "term": "OSTEOMYELITIS ACUTE",
      "count": 5
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 5
    },
    {
      "term": "TOXIC SKIN ERUPTION",
      "count": 5
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 4
    },
    {
      "term": "ABSCESS",
      "count": 4
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 4
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 4
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 4
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 4
    },
    {
      "term": "COUGH",
      "count": 4
    },
    {
      "term": "COVID-19",
      "count": 4
    },
    {
      "term": "DENTAL CARIES",
      "count": 4
    },
    {
      "term": "ERYTHEMA",
      "count": 4
    },
    {
      "term": "FATIGUE",
      "count": 4
    },
    {
      "term": "HAEMATOMA",
      "count": 4
    }
  ]
}