{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 92
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 89
    },
    {
      "term": "NAUSEA",
      "count": 81
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 78
    },
    {
      "term": "RASH",
      "count": 76
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 63
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 62
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 62
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 56
    },
    {
      "term": "DYSPNOEA",
      "count": 51
    },
    {
      "term": "PYREXIA",
      "count": 51
    },
    {
      "term": "DIARRHOEA",
      "count": 50
    },
    {
      "term": "HYPOTENSION",
      "count": 45
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 43
    },
    {
      "term": "VOMITING",
      "count": 43
    },
    {
      "term": "MYCOBACTERIUM ABSCESSUS INFECTION",
      "count": 40
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 39
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 39
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 37
    },
    {
      "term": "ANAPHYLACTIC SHOCK",
      "count": 36
    },
    {
      "term": "PNEUMONIA",
      "count": 35
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 34
    },
    {
      "term": "OTOTOXICITY",
      "count": 33
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 32
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 32
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 32
    },
    {
      "term": "RENAL FAILURE",
      "count": 28
    },
    {
      "term": "DEAFNESS",
      "count": 26
    },
    {
      "term": "PRURITUS",
      "count": 26
    },
    {
      "term": "TACHYCARDIA",
      "count": 25
    },
    {
      "term": "CARDIAC ARREST",
      "count": 24
    },
    {
      "term": "EOSINOPHILIA",
      "count": 23
    },
    {
      "term": "NEUTROPENIA",
      "count": 23
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 22
    },
    {
      "term": "CIRCULATORY COLLAPSE",
      "count": 21
    },
    {
      "term": "PAIN",
      "count": 21
    },
    {
      "term": "CHEST PAIN",
      "count": 20
    },
    {
      "term": "COUGH",
      "count": 20
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 20
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 20
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 20
    },
    {
      "term": "ANAEMIA",
      "count": 19
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 19
    },
    {
      "term": "DEATH",
      "count": 19
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 19
    },
    {
      "term": "LEUKOPENIA",
      "count": 19
    },
    {
      "term": "PREMATURE BABY",
      "count": 19
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 19
    },
    {
      "term": "ASTHENIA",
      "count": 18
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 18
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 18
    },
    {
      "term": "SEPSIS",
      "count": 18
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 17
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 17
    },
    {
      "term": "URTICARIA",
      "count": 17
    },
    {
      "term": "DECREASED APPETITE",
      "count": 16
    },
    {
      "term": "DRUG INTERACTION",
      "count": 16
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 16
    },
    {
      "term": "PULMONARY MASS",
      "count": 16
    },
    {
      "term": "SYSTEMIC MASTOCYTOSIS",
      "count": 16
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 16
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 15
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 15
    },
    {
      "term": "ERYTHEMA",
      "count": 15
    },
    {
      "term": "HEADACHE",
      "count": 15
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 15
    },
    {
      "term": "MALAISE",
      "count": 15
    },
    {
      "term": "PANCREATITIS ACUTE",
      "count": 15
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 15
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 14
    },
    {
      "term": "CHILLS",
      "count": 14
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 14
    },
    {
      "term": "HEPATOCELLULAR INJURY",
      "count": 14
    },
    {
      "term": "PANCYTOPENIA",
      "count": 14
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 14
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 14
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 13
    },
    {
      "term": "CATATONIA",
      "count": 13
    },
    {
      "term": "DIZZINESS",
      "count": 13
    },
    {
      "term": "FATIGUE",
      "count": 13
    },
    {
      "term": "HAEMOPTYSIS",
      "count": 13
    },
    {
      "term": "NEUROTOXICITY",
      "count": 13
    },
    {
      "term": "PANCREATITIS",
      "count": 13
    },
    {
      "term": "RENAL INJURY",
      "count": 13
    },
    {
      "term": "TREMOR",
      "count": 13
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 13
    },
    {
      "term": "BRONCHIECTASIS",
      "count": 12
    },
    {
      "term": "BRONCHOSPASM",
      "count": 12
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 12
    },
    {
      "term": "LOW BIRTH WEIGHT BABY",
      "count": 12
    },
    {
      "term": "MYCOBACTERIUM CHELONAE INFECTION",
      "count": 12
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 12
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 12
    },
    {
      "term": "AGITATION",
      "count": 11
    },
    {
      "term": "ANXIETY",
      "count": 11
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 11
    },
    {
      "term": "BRADYCARDIA",
      "count": 11
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 11
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 11
    },
    {
      "term": "DEPRESSION",
      "count": 11
    }
  ]
}