{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PYREXIA",
      "count": 187
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 185
    },
    {
      "term": "PNEUMONIA",
      "count": 135
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 103
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 102
    },
    {
      "term": "OFF LABEL USE",
      "count": 85
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 85
    },
    {
      "term": "ANAEMIA",
      "count": 78
    },
    {
      "term": "NEUTROPENIA",
      "count": 75
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 75
    },
    {
      "term": "DIARRHOEA",
      "count": 72
    },
    {
      "term": "SEPSIS",
      "count": 70
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 69
    },
    {
      "term": "RASH",
      "count": 68
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 66
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 58
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 57
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 55
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 53
    },
    {
      "term": "RENAL FAILURE",
      "count": 50
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 46
    },
    {
      "term": "INFECTION",
      "count": 44
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 43
    },
    {
      "term": "DYSPNOEA",
      "count": 43
    },
    {
      "term": "NAUSEA",
      "count": 43
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 42
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 41
    },
    {
      "term": "NEUROTOXICITY",
      "count": 40
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 38
    },
    {
      "term": "HYPOTENSION",
      "count": 38
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 38
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 38
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 38
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 37
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 36
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 35
    },
    {
      "term": "LIVER DISORDER",
      "count": 35
    },
    {
      "term": "PRURITUS",
      "count": 35
    },
    {
      "term": "DEATH",
      "count": 34
    },
    {
      "term": "DECREASED APPETITE",
      "count": 34
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 33
    },
    {
      "term": "VOMITING",
      "count": 33
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 32
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 32
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 31
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 30
    },
    {
      "term": "PANCYTOPENIA",
      "count": 30
    },
    {
      "term": "STOMATITIS",
      "count": 29
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 28
    },
    {
      "term": "CONSTIPATION",
      "count": 27
    },
    {
      "term": "MALAISE",
      "count": 27
    },
    {
      "term": "OVERDOSE",
      "count": 27
    },
    {
      "term": "STATUS EPILEPTICUS",
      "count": 27
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 26
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 26
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 26
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 25
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 25
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 25
    },
    {
      "term": "CYTOMEGALOVIRUS TEST POSITIVE",
      "count": 24
    },
    {
      "term": "DELIRIUM",
      "count": 24
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 24
    },
    {
      "term": "FATIGUE",
      "count": 24
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 24
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 24
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 24
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 23
    },
    {
      "term": "BACTERAEMIA",
      "count": 23
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 23
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 23
    },
    {
      "term": "CLOSTRIDIUM DIFFICILE COLITIS",
      "count": 22
    },
    {
      "term": "COVID-19",
      "count": 22
    },
    {
      "term": "DRUG INTERACTION",
      "count": 22
    },
    {
      "term": "LEUKOPENIA",
      "count": 22
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 21
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 21
    },
    {
      "term": "COUGH",
      "count": 21
    },
    {
      "term": "ERYTHEMA",
      "count": 21
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 21
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 21
    },
    {
      "term": "PAIN",
      "count": 21
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 20
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 20
    },
    {
      "term": "DRUG ERUPTION",
      "count": 20
    },
    {
      "term": "SEIZURE",
      "count": 20
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 20
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 20
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 19
    },
    {
      "term": "CELLULITIS",
      "count": 19
    },
    {
      "term": "HYPOXIA",
      "count": 19
    },
    {
      "term": "STAPHYLOCOCCAL SEPSIS",
      "count": 19
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 18
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 18
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 18
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 18
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 18
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 18
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 18
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 18
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 17
    }
  ]
}