{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 352
    },
    {
      "term": "OFF LABEL USE",
      "count": 87
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 81
    },
    {
      "term": "PNEUMONIA",
      "count": 64
    },
    {
      "term": "PYREXIA",
      "count": 64
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 64
    },
    {
      "term": "DEATH",
      "count": 63
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 61
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 61
    },
    {
      "term": "SEPSIS",
      "count": 57
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 56
    },
    {
      "term": "DRUG INTERACTION",
      "count": 53
    },
    {
      "term": "SYSTEMIC CANDIDA",
      "count": 53
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 52
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 51
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 51
    },
    {
      "term": "RENAL FAILURE",
      "count": 49
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 48
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 44
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 43
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 42
    },
    {
      "term": "NEUTROPENIA",
      "count": 42
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 41
    },
    {
      "term": "DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS",
      "count": 40
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 38
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 38
    },
    {
      "term": "SYSTEMIC MYCOSIS",
      "count": 37
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 36
    },
    {
      "term": "ANAEMIA",
      "count": 36
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 35
    },
    {
      "term": "DIARRHOEA",
      "count": 35
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 35
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 35
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 34
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 32
    },
    {
      "term": "TOXIC EPIDERMAL NECROLYSIS",
      "count": 32
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 31
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 31
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 30
    },
    {
      "term": "RASH",
      "count": 28
    },
    {
      "term": "LEUKOPENIA",
      "count": 27
    },
    {
      "term": "HYPOTENSION",
      "count": 26
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 25
    },
    {
      "term": "NAUSEA",
      "count": 25
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 24
    },
    {
      "term": "PANCYTOPENIA",
      "count": 23
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 23
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 23
    },
    {
      "term": "VOMITING",
      "count": 23
    },
    {
      "term": "ACUTE GENERALISED EXANTHEMATOUS PUSTULOSIS",
      "count": 22
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 22
    },
    {
      "term": "EOSINOPHILIA",
      "count": 22
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 22
    },
    {
      "term": "ACTINIC KERATOSIS",
      "count": 21
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 21
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 21
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 21
    },
    {
      "term": "DYSPLASTIC NAEVUS",
      "count": 21
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 21
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 21
    },
    {
      "term": "ORAL CANDIDIASIS",
      "count": 21
    },
    {
      "term": "PHOTODERMATOSIS",
      "count": 21
    },
    {
      "term": "PHOTOSENSITIVITY REACTION",
      "count": 21
    },
    {
      "term": "SOLAR LENTIGO",
      "count": 21
    },
    {
      "term": "SQUAMOUS CELL CARCINOMA OF SKIN",
      "count": 21
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 21
    },
    {
      "term": "CHOLESTASIS",
      "count": 20
    },
    {
      "term": "DYSPNOEA",
      "count": 20
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 20
    },
    {
      "term": "UNRESPONSIVE TO STIMULI",
      "count": 20
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 20
    },
    {
      "term": "BACK PAIN",
      "count": 19
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 19
    },
    {
      "term": "HYPERBILIRUBINAEMIA",
      "count": 19
    },
    {
      "term": "MULTI-ORGAN FAILURE",
      "count": 19
    },
    {
      "term": "PROTEIN URINE PRESENT",
      "count": 19
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 19
    },
    {
      "term": "STEVENS-JOHNSON SYNDROME",
      "count": 19
    },
    {
      "term": "TOXIC SKIN ERUPTION",
      "count": 19
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 19
    },
    {
      "term": "BACTERAEMIA",
      "count": 18
    },
    {
      "term": "CARDIAC ARREST",
      "count": 18
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 18
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 18
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 18
    },
    {
      "term": "INFECTION",
      "count": 18
    },
    {
      "term": "MUCORMYCOSIS",
      "count": 18
    },
    {
      "term": "PROCEDURAL PAIN",
      "count": 18
    },
    {
      "term": "STAPHYLOCOCCAL BACTERAEMIA",
      "count": 18
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 18
    },
    {
      "term": "BLOOD CULTURE POSITIVE",
      "count": 17
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 17
    },
    {
      "term": "INCISION SITE PAIN",
      "count": 17
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 17
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 17
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 17
    },
    {
      "term": "NEUTROPHIL COUNT INCREASED",
      "count": 17
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 16
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 16
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 16
    }
  ]
}