{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 493
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 381
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 289
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 268
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 228
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 209
    },
    {
      "term": "PYREXIA",
      "count": 205
    },
    {
      "term": "NEUTROPENIA",
      "count": 204
    },
    {
      "term": "PNEUMONIA",
      "count": 190
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 186
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 173
    },
    {
      "term": "INFECTION",
      "count": 157
    },
    {
      "term": "DIARRHOEA",
      "count": 156
    },
    {
      "term": "SEPSIS",
      "count": 152
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 151
    },
    {
      "term": "ANAEMIA",
      "count": 116
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 112
    },
    {
      "term": "DEATH",
      "count": 110
    },
    {
      "term": "SECOND PRIMARY MALIGNANCY",
      "count": 106
    },
    {
      "term": "PANCYTOPENIA",
      "count": 103
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 94
    },
    {
      "term": "MALIGNANT TRANSFORMATION",
      "count": 88
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 78
    },
    {
      "term": "NAUSEA",
      "count": 78
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 78
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 75
    },
    {
      "term": "STOMATITIS",
      "count": 74
    },
    {
      "term": "LEUKOPENIA",
      "count": 73
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA RECURRENT",
      "count": 71
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 71
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 69
    },
    {
      "term": "VOMITING",
      "count": 69
    },
    {
      "term": "COLITIS",
      "count": 68
    },
    {
      "term": "NON-HODGKIN^S LYMPHOMA RECURRENT",
      "count": 68
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 67
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 66
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 65
    },
    {
      "term": "DYSPNOEA",
      "count": 65
    },
    {
      "term": "DIFFUSE LARGE B-CELL LYMPHOMA",
      "count": 64
    },
    {
      "term": "PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY",
      "count": 64
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 63
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 63
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 62
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 62
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 58
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 57
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 56
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 54
    },
    {
      "term": "STEM CELL TRANSPLANT",
      "count": 54
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 53
    },
    {
      "term": "BASAL CELL CARCINOMA",
      "count": 51
    },
    {
      "term": "CYTOPENIA",
      "count": 51
    },
    {
      "term": "MYOSITIS",
      "count": 51
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 51
    },
    {
      "term": "RENAL FAILURE",
      "count": 51
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 49
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 49
    },
    {
      "term": "PNEUMONITIS",
      "count": 49
    },
    {
      "term": "RASH",
      "count": 49
    },
    {
      "term": "HYPOTENSION",
      "count": 48
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 47
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 47
    },
    {
      "term": "ASTHENIA",
      "count": 46
    },
    {
      "term": "FATIGUE",
      "count": 46
    },
    {
      "term": "LYMPHOMA",
      "count": 45
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 44
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 44
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 44
    },
    {
      "term": "DRUG INTERACTION",
      "count": 42
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 42
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 41
    },
    {
      "term": "BACTERAEMIA",
      "count": 40
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 40
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 38
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 38
    },
    {
      "term": "CARDIOTOXICITY",
      "count": 37
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 37
    },
    {
      "term": "PULMONARY TOXICITY",
      "count": 37
    },
    {
      "term": "BLOOD STEM CELL TRANSPLANT FAILURE",
      "count": 36
    },
    {
      "term": "COVID-19",
      "count": 36
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 36
    },
    {
      "term": "HYPOGAMMAGLOBULINAEMIA",
      "count": 36
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 35
    },
    {
      "term": "LYMPHOPENIA",
      "count": 35
    },
    {
      "term": "VENOOCCLUSIVE DISEASE",
      "count": 35
    },
    {
      "term": "COUGH",
      "count": 34
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 34
    },
    {
      "term": "HERPES ZOSTER",
      "count": 34
    },
    {
      "term": "JC VIRUS INFECTION",
      "count": 34
    },
    {
      "term": "KAPOSI^S SARCOMA",
      "count": 34
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 34
    },
    {
      "term": "NEUTROPENIC COLITIS",
      "count": 33
    },
    {
      "term": "NON-HODGKIN^S LYMPHOMA",
      "count": 33
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 32
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 32
    },
    {
      "term": "HEADACHE",
      "count": 32
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 32
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 32
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 32
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 31
    }
  ]
}