{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 8598
    },
    {
      "term": "NEUTROPENIA",
      "count": 7554
    },
    {
      "term": "ANAEMIA",
      "count": 7307
    },
    {
      "term": "NAUSEA",
      "count": 7229
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 6650
    },
    {
      "term": "DIARRHOEA",
      "count": 6329
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 6105
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 6082
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 6006
    },
    {
      "term": "DYSPNOEA",
      "count": 5689
    },
    {
      "term": "VOMITING",
      "count": 5292
    },
    {
      "term": "PYREXIA",
      "count": 4931
    },
    {
      "term": "FATIGUE",
      "count": 4797
    },
    {
      "term": "DEATH",
      "count": 4368
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 4338
    },
    {
      "term": "ASTHENIA",
      "count": 3942
    },
    {
      "term": "PANCYTOPENIA",
      "count": 3712
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 3525
    },
    {
      "term": "PNEUMONIA",
      "count": 3370
    },
    {
      "term": "RASH",
      "count": 3205
    },
    {
      "term": "DECREASED APPETITE",
      "count": 2906
    },
    {
      "term": "SEPSIS",
      "count": 2806
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 2805
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 2689
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 2683
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 2671
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 2612
    },
    {
      "term": "ALOPECIA",
      "count": 2578
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 2534
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 2396
    },
    {
      "term": "ERYTHEMA",
      "count": 2363
    },
    {
      "term": "DEHYDRATION",
      "count": 2349
    },
    {
      "term": "HYPOTENSION",
      "count": 2349
    },
    {
      "term": "LEUKOPENIA",
      "count": 2265
    },
    {
      "term": "CONSTIPATION",
      "count": 2196
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 2161
    },
    {
      "term": "PRURITUS",
      "count": 1901
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 1897
    },
    {
      "term": "MALAISE",
      "count": 1882
    },
    {
      "term": "COUGH",
      "count": 1765
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 1736
    },
    {
      "term": "PAIN",
      "count": 1728
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 1709
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 1676
    },
    {
      "term": "HYPERTENSION",
      "count": 1647
    },
    {
      "term": "INFECTION",
      "count": 1613
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 1610
    },
    {
      "term": "DIZZINESS",
      "count": 1592
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 1576
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 1555
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 1535
    },
    {
      "term": "PNEUMONITIS",
      "count": 1467
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 1427
    },
    {
      "term": "CHEST PAIN",
      "count": 1401
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 1376
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 1374
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 1372
    },
    {
      "term": "HEADACHE",
      "count": 1362
    },
    {
      "term": "RENAL FAILURE",
      "count": 1345
    },
    {
      "term": "COLITIS",
      "count": 1337
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 1310
    },
    {
      "term": "ARTHRALGIA",
      "count": 1299
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 1270
    },
    {
      "term": "FLUSHING",
      "count": 1241
    },
    {
      "term": "BACK PAIN",
      "count": 1233
    },
    {
      "term": "TACHYCARDIA",
      "count": 1225
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 1219
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 1214
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 1169
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 1142
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 1142
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 1119
    },
    {
      "term": "DYSPHAGIA",
      "count": 1091
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 1081
    },
    {
      "term": "EPISTAXIS",
      "count": 1052
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 1050
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 1033
    },
    {
      "term": "STOMATITIS",
      "count": 1016
    },
    {
      "term": "PARAESTHESIA",
      "count": 987
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 980
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 968
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 966
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 955
    },
    {
      "term": "CHILLS",
      "count": 946
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 944
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 942
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 924
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 904
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 888
    },
    {
      "term": "CYTOPENIA",
      "count": 886
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 867
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 864
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 864
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 848
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 843
    },
    {
      "term": "MYALGIA",
      "count": 839
    },
    {
      "term": "METASTASES TO LIVER",
      "count": 828
    },
    {
      "term": "SYNCOPE",
      "count": 827
    },
    {
      "term": "ANXIETY",
      "count": 824
    },
    {
      "term": "HYPOMAGNESAEMIA",
      "count": 806
    }
  ]
}