{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 85
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 27
    },
    {
      "term": "EPISTAXIS",
      "count": 24
    },
    {
      "term": "ADAMTS13 ACTIVITY DECREASED",
      "count": 23
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 21
    },
    {
      "term": "HEADACHE",
      "count": 19
    },
    {
      "term": "THROMBOTIC THROMBOCYTOPENIC PURPURA",
      "count": 19
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 16
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 16
    },
    {
      "term": "DRUG EFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 14
    },
    {
      "term": "HAEMORRHAGE",
      "count": 14
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 14
    },
    {
      "term": "CONTUSION",
      "count": 13
    },
    {
      "term": "PYREXIA",
      "count": 13
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 12
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 11
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 11
    },
    {
      "term": "HYPERTENSION",
      "count": 11
    },
    {
      "term": "THROMBOSIS",
      "count": 11
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 10
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 10
    },
    {
      "term": "FATIGUE",
      "count": 10
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 10
    },
    {
      "term": "FOETAL GROWTH RESTRICTION",
      "count": 10
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 10
    },
    {
      "term": "INJECTION SITE PAIN",
      "count": 10
    },
    {
      "term": "ASTHENIA",
      "count": 9
    },
    {
      "term": "INJECTION SITE BRUISING",
      "count": 9
    },
    {
      "term": "NAUSEA",
      "count": 9
    },
    {
      "term": "OLIGOHYDRAMNIOS",
      "count": 9
    },
    {
      "term": "DIARRHOEA",
      "count": 8
    },
    {
      "term": "PARAESTHESIA",
      "count": 8
    },
    {
      "term": "PLACENTAL OEDEMA",
      "count": 8
    },
    {
      "term": "PNEUMONIA",
      "count": 8
    },
    {
      "term": "SEIZURE",
      "count": 8
    },
    {
      "term": "VAGINAL HAEMORRHAGE",
      "count": 8
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 7
    },
    {
      "term": "GINGIVAL BLEEDING",
      "count": 7
    },
    {
      "term": "IMMUNE THROMBOCYTOPENIA",
      "count": 7
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 7
    },
    {
      "term": "ANAEMIA",
      "count": 6
    },
    {
      "term": "BACK PAIN",
      "count": 6
    },
    {
      "term": "CARDIAC ARREST",
      "count": 6
    },
    {
      "term": "COVID-19",
      "count": 6
    },
    {
      "term": "DIZZINESS",
      "count": 6
    },
    {
      "term": "DYSPNOEA",
      "count": 6
    },
    {
      "term": "HAEMOLYTIC ANAEMIA",
      "count": 6
    },
    {
      "term": "INFECTION",
      "count": 6
    },
    {
      "term": "MELAENA",
      "count": 6
    },
    {
      "term": "PLACENTAL INSUFFICIENCY",
      "count": 6
    },
    {
      "term": "PRE-ECLAMPSIA",
      "count": 6
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 6
    },
    {
      "term": "SERUM SICKNESS",
      "count": 6
    },
    {
      "term": "ADAMTS13 ACTIVITY ABNORMAL",
      "count": 5
    },
    {
      "term": "ANXIETY",
      "count": 5
    },
    {
      "term": "ARTHRALGIA",
      "count": 5
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 5
    },
    {
      "term": "CONSTIPATION",
      "count": 5
    },
    {
      "term": "FOETAL DEATH",
      "count": 5
    },
    {
      "term": "FOETAL DISTRESS SYNDROME",
      "count": 5
    },
    {
      "term": "FOOD POISONING",
      "count": 5
    },
    {
      "term": "LIVER FUNCTION TEST ABNORMAL",
      "count": 5
    },
    {
      "term": "MYALGIA",
      "count": 5
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 5
    },
    {
      "term": "RASH",
      "count": 5
    },
    {
      "term": "RED BLOOD CELL COUNT DECREASED",
      "count": 5
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 4
    },
    {
      "term": "CATHETER SITE HAEMORRHAGE",
      "count": 4
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 4
    },
    {
      "term": "HEAVY MENSTRUAL BLEEDING",
      "count": 4
    },
    {
      "term": "HOSPITALISATION",
      "count": 4
    },
    {
      "term": "HUMORAL IMMUNE DEFECT",
      "count": 4
    },
    {
      "term": "HYPOTENSION",
      "count": 4
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 4
    },
    {
      "term": "INJECTION SITE ERYTHEMA",
      "count": 4
    },
    {
      "term": "INJECTION SITE HAEMORRHAGE",
      "count": 4
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 4
    },
    {
      "term": "LYMPHADENOPATHY",
      "count": 4
    },
    {
      "term": "MALAISE",
      "count": 4
    },
    {
      "term": "NEUROTOXICITY",
      "count": 4
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 4
    },
    {
      "term": "PLATELET COUNT ABNORMAL",
      "count": 4
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 4
    },
    {
      "term": "RASH PRURITIC",
      "count": 4
    },
    {
      "term": "REBOUND EFFECT",
      "count": 4
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 4
    },
    {
      "term": "SEPSIS",
      "count": 4
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 4
    },
    {
      "term": "SKIN REACTION",
      "count": 4
    },
    {
      "term": "SUBDURAL HAEMATOMA",
      "count": 4
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 4
    },
    {
      "term": "VISION BLURRED",
      "count": 4
    },
    {
      "term": "VOMITING",
      "count": 4
    },
    {
      "term": "WHITE BLOOD CELL COUNT INCREASED",
      "count": 4
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 3
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 3
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 3
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 3
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 3
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 3
    }
  ]
}