{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "RENAL FAILURE",
      "count": 502
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 465
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 438
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 393
    },
    {
      "term": "DIARRHOEA",
      "count": 345
    },
    {
      "term": "NAUSEA",
      "count": 300
    },
    {
      "term": "FATIGUE",
      "count": 275
    },
    {
      "term": "DEATH",
      "count": 262
    },
    {
      "term": "DYSPNOEA",
      "count": 254
    },
    {
      "term": "NEPHROGENIC ANAEMIA",
      "count": 212
    },
    {
      "term": "PAIN",
      "count": 211
    },
    {
      "term": "VOMITING",
      "count": 197
    },
    {
      "term": "ASTHENIA",
      "count": 195
    },
    {
      "term": "PRURITUS",
      "count": 195
    },
    {
      "term": "PNEUMONIA",
      "count": 190
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 171
    },
    {
      "term": "ANAEMIA",
      "count": 170
    },
    {
      "term": "OFF LABEL USE",
      "count": 164
    },
    {
      "term": "DIZZINESS",
      "count": 159
    },
    {
      "term": "HYPOTENSION",
      "count": 153
    },
    {
      "term": "HEADACHE",
      "count": 150
    },
    {
      "term": "FALL",
      "count": 147
    },
    {
      "term": "ANXIETY",
      "count": 146
    },
    {
      "term": "MALAISE",
      "count": 146
    },
    {
      "term": "FLUSHING",
      "count": 145
    },
    {
      "term": "PYREXIA",
      "count": 130
    },
    {
      "term": "ARTHRALGIA",
      "count": 122
    },
    {
      "term": "SEPSIS",
      "count": 121
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 119
    },
    {
      "term": "CONSTIPATION",
      "count": 118
    },
    {
      "term": "HYPERPARATHYROIDISM SECONDARY",
      "count": 115
    },
    {
      "term": "RASH",
      "count": 110
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 107
    },
    {
      "term": "RENAL INJURY",
      "count": 104
    },
    {
      "term": "HYPERTENSION",
      "count": 102
    },
    {
      "term": "DEPRESSION",
      "count": 100
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 99
    },
    {
      "term": "CARDIAC ARREST",
      "count": 94
    },
    {
      "term": "DECREASED APPETITE",
      "count": 91
    },
    {
      "term": "BACK PAIN",
      "count": 90
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 90
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 89
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 86
    },
    {
      "term": "CHEST PAIN",
      "count": 85
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 85
    },
    {
      "term": "COUGH",
      "count": 83
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 83
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 79
    },
    {
      "term": "DIALYSIS",
      "count": 79
    },
    {
      "term": "INSOMNIA",
      "count": 79
    },
    {
      "term": "ERYTHEMA",
      "count": 77
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 75
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 72
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 72
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 72
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 72
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 72
    },
    {
      "term": "CHRONIC KIDNEY DISEASE-MINERAL AND BONE DISORDER",
      "count": 71
    },
    {
      "term": "HOSPITALISATION",
      "count": 71
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 71
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 70
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 69
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 69
    },
    {
      "term": "PARAESTHESIA",
      "count": 66
    },
    {
      "term": "ANHEDONIA",
      "count": 65
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 65
    },
    {
      "term": "DRUG INTERACTION",
      "count": 65
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 65
    },
    {
      "term": "SOMNOLENCE",
      "count": 63
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 62
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 61
    },
    {
      "term": "DEHYDRATION",
      "count": 61
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 59
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 59
    },
    {
      "term": "HYPERCALCAEMIA",
      "count": 59
    },
    {
      "term": "NEUTROPENIA",
      "count": 58
    },
    {
      "term": "PULMONARY OEDEMA",
      "count": 58
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 57
    },
    {
      "term": "NEPHROGENIC SYSTEMIC FIBROSIS",
      "count": 56
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 56
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 56
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 56
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 55
    },
    {
      "term": "PERITONITIS",
      "count": 54
    },
    {
      "term": "TREATMENT NONCOMPLIANCE",
      "count": 54
    },
    {
      "term": "TREMOR",
      "count": 53
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 53
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 52
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 50
    },
    {
      "term": "INFECTION",
      "count": 50
    },
    {
      "term": "PERITONITIS BACTERIAL",
      "count": 50
    },
    {
      "term": "RENAL FAILURE ACUTE",
      "count": 50
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 49
    },
    {
      "term": "COVID-19",
      "count": 49
    },
    {
      "term": "SYNCOPE",
      "count": 49
    },
    {
      "term": "CALCIPHYLAXIS",
      "count": 48
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 48
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 47
    },
    {
      "term": "ECONOMIC PROBLEM",
      "count": 47
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 47
    }
  ]
}