{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "NAUSEA",
      "count": 1529
    },
    {
      "term": "OFF LABEL USE",
      "count": 1201
    },
    {
      "term": "DIARRHOEA",
      "count": 1190
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 1123
    },
    {
      "term": "VOMITING",
      "count": 1093
    },
    {
      "term": "DYSPNOEA",
      "count": 1077
    },
    {
      "term": "RENAL FAILURE",
      "count": 1076
    },
    {
      "term": "FATIGUE",
      "count": 1033
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 965
    },
    {
      "term": "DEATH",
      "count": 916
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 874
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 854
    },
    {
      "term": "PAIN",
      "count": 834
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 825
    },
    {
      "term": "HEADACHE",
      "count": 822
    },
    {
      "term": "CONSTIPATION",
      "count": 797
    },
    {
      "term": "ANAEMIA",
      "count": 781
    },
    {
      "term": "ASTHENIA",
      "count": 771
    },
    {
      "term": "PYREXIA",
      "count": 754
    },
    {
      "term": "END STAGE RENAL DISEASE",
      "count": 730
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 695
    },
    {
      "term": "PNEUMONIA",
      "count": 672
    },
    {
      "term": "MALAISE",
      "count": 636
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 586
    },
    {
      "term": "FALL",
      "count": 560
    },
    {
      "term": "DIZZINESS",
      "count": 557
    },
    {
      "term": "SEPSIS",
      "count": 539
    },
    {
      "term": "HYPERTENSION",
      "count": 538
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 528
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 495
    },
    {
      "term": "RECALLED PRODUCT",
      "count": 487
    },
    {
      "term": "PRURITUS",
      "count": 479
    },
    {
      "term": "ARTHRALGIA",
      "count": 467
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 461
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 450
    },
    {
      "term": "HYPERCALCAEMIA",
      "count": 426
    },
    {
      "term": "DECREASED APPETITE",
      "count": 421
    },
    {
      "term": "HYPOTENSION",
      "count": 412
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 400
    },
    {
      "term": "COUGH",
      "count": 397
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 396
    },
    {
      "term": "ABDOMINAL DISTENSION",
      "count": 382
    },
    {
      "term": "RASH",
      "count": 380
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 371
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 370
    },
    {
      "term": "BACK PAIN",
      "count": 365
    },
    {
      "term": "NEPHROGENIC ANAEMIA",
      "count": 364
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 361
    },
    {
      "term": "ANXIETY",
      "count": 357
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 355
    },
    {
      "term": "SOMNOLENCE",
      "count": 345
    },
    {
      "term": "STRESS",
      "count": 339
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 336
    },
    {
      "term": "HYPERPARATHYROIDISM SECONDARY",
      "count": 327
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 326
    },
    {
      "term": "DRUG INTERACTION",
      "count": 316
    },
    {
      "term": "ERYTHEMA",
      "count": 307
    },
    {
      "term": "ASCITES",
      "count": 303
    },
    {
      "term": "CHEST PAIN",
      "count": 299
    },
    {
      "term": "DEHYDRATION",
      "count": 293
    },
    {
      "term": "THROMBOSIS",
      "count": 289
    },
    {
      "term": "DRY MOUTH",
      "count": 281
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 280
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 277
    },
    {
      "term": "CARDIOGENIC SHOCK",
      "count": 276
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 274
    },
    {
      "term": "APPENDICITIS",
      "count": 271
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 268
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 267
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 265
    },
    {
      "term": "APPENDICOLITH",
      "count": 254
    },
    {
      "term": "DEPRESSION",
      "count": 249
    },
    {
      "term": "PARAESTHESIA",
      "count": 245
    },
    {
      "term": "RENAL INJURY",
      "count": 241
    },
    {
      "term": "SWELLING",
      "count": 241
    },
    {
      "term": "BLOOD CALCIUM DECREASED",
      "count": 237
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 237
    },
    {
      "term": "DYSPEPSIA",
      "count": 234
    },
    {
      "term": "INSOMNIA",
      "count": 231
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 231
    },
    {
      "term": "TREMOR",
      "count": 230
    },
    {
      "term": "CHRONIC OBSTRUCTIVE PULMONARY DISEASE",
      "count": 222
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 222
    },
    {
      "term": "VENTRICULAR FIBRILLATION",
      "count": 221
    },
    {
      "term": "BLOOD PHOSPHORUS INCREASED",
      "count": 220
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 218
    },
    {
      "term": "GOUT",
      "count": 217
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 216
    },
    {
      "term": "HAEMATOCHEZIA",
      "count": 215
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 214
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 213
    },
    {
      "term": "MYALGIA",
      "count": 211
    },
    {
      "term": "HOSPITALISATION",
      "count": 208
    },
    {
      "term": "CARDIAC ARREST",
      "count": 207
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 205
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 202
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 200
    },
    {
      "term": "COVID-19",
      "count": 197
    },
    {
      "term": "RENAL DISORDER",
      "count": 195
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 194
    }
  ]
}