{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DEPENDENCE",
      "count": 2282
    },
    {
      "term": "OVERDOSE",
      "count": 1309
    },
    {
      "term": "PAIN",
      "count": 587
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 580
    },
    {
      "term": "ANXIETY",
      "count": 565
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 530
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 508
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 498
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 435
    },
    {
      "term": "DEATH",
      "count": 388
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 316
    },
    {
      "term": "NAUSEA",
      "count": 303
    },
    {
      "term": "DEPRESSION",
      "count": 234
    },
    {
      "term": "OFF LABEL USE",
      "count": 234
    },
    {
      "term": "DRUG ABUSE",
      "count": 233
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 225
    },
    {
      "term": "VOMITING",
      "count": 221
    },
    {
      "term": "ILL-DEFINED DISORDER",
      "count": 219
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 215
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 210
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 209
    },
    {
      "term": "HEADACHE",
      "count": 191
    },
    {
      "term": "DIZZINESS",
      "count": 166
    },
    {
      "term": "DIARRHOEA",
      "count": 165
    },
    {
      "term": "FATIGUE",
      "count": 155
    },
    {
      "term": "INSOMNIA",
      "count": 151
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 143
    },
    {
      "term": "DYSPNOEA",
      "count": 129
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 127
    },
    {
      "term": "ARTHRALGIA",
      "count": 123
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 120
    },
    {
      "term": "FALL",
      "count": 117
    },
    {
      "term": "ASTHENIA",
      "count": 116
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 116
    },
    {
      "term": "PREMATURE BABY",
      "count": 105
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 105
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 105
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 100
    },
    {
      "term": "PRURITUS",
      "count": 100
    },
    {
      "term": "RASH",
      "count": 98
    },
    {
      "term": "PYREXIA",
      "count": 97
    },
    {
      "term": "PREMATURE DELIVERY",
      "count": 96
    },
    {
      "term": "MALAISE",
      "count": 95
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 94
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 93
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 92
    },
    {
      "term": "MIGRAINE",
      "count": 91
    },
    {
      "term": "SOMNOLENCE",
      "count": 90
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 89
    },
    {
      "term": "DRUG INTERACTION",
      "count": 84
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 83
    },
    {
      "term": "DECREASED APPETITE",
      "count": 82
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 80
    },
    {
      "term": "COMA",
      "count": 79
    },
    {
      "term": "ACCIDENTAL OVERDOSE",
      "count": 77
    },
    {
      "term": "CONSTIPATION",
      "count": 77
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 76
    },
    {
      "term": "PARAESTHESIA",
      "count": 76
    },
    {
      "term": "STOMATITIS",
      "count": 76
    },
    {
      "term": "BLEPHAROSPASM",
      "count": 75
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 75
    },
    {
      "term": "EXPOSURE VIA BREAST MILK",
      "count": 73
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 73
    },
    {
      "term": "TACHYCARDIA",
      "count": 73
    },
    {
      "term": "ASTHMA",
      "count": 72
    },
    {
      "term": "DRY MOUTH",
      "count": 72
    },
    {
      "term": "PNEUMONIA",
      "count": 72
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 71
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 71
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 70
    },
    {
      "term": "INFLAMMATION",
      "count": 70
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 70
    },
    {
      "term": "IRRITABLE BOWEL SYNDROME",
      "count": 69
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 69
    },
    {
      "term": "SEPSIS",
      "count": 69
    },
    {
      "term": "SLEEP DISORDER",
      "count": 69
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 69
    },
    {
      "term": "INJURY",
      "count": 68
    },
    {
      "term": "CHILLS",
      "count": 67
    },
    {
      "term": "JOINT SWELLING",
      "count": 67
    },
    {
      "term": "HYPERTENSION",
      "count": 66
    },
    {
      "term": "TASTE DISORDER",
      "count": 66
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 65
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 63
    },
    {
      "term": "DYSPHAGIA",
      "count": 63
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 63
    },
    {
      "term": "PERIPHERAL VENOUS DISEASE",
      "count": 62
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 61
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 60
    },
    {
      "term": "BACK INJURY",
      "count": 59
    },
    {
      "term": "HEPATIC ENZYME INCREASED",
      "count": 59
    },
    {
      "term": "IMPAIRED HEALING",
      "count": 59
    },
    {
      "term": "SYNOVITIS",
      "count": 59
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 59
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 58
    },
    {
      "term": "GLOSSODYNIA",
      "count": 58
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 58
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 58
    },
    {
      "term": "BLISTER",
      "count": 57
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 57
    }
  ]
}