{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 159
    },
    {
      "term": "NAUSEA",
      "count": 148
    },
    {
      "term": "HEADACHE",
      "count": 102
    },
    {
      "term": "VOMITING",
      "count": 97
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 94
    },
    {
      "term": "INJECTION SITE REACTION",
      "count": 90
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 87
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 85
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 77
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 61
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 61
    },
    {
      "term": "PAIN",
      "count": 59
    },
    {
      "term": "DRUG ABUSE",
      "count": 55
    },
    {
      "term": "MALAISE",
      "count": 54
    },
    {
      "term": "OFF LABEL USE",
      "count": 52
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 51
    },
    {
      "term": "ANXIETY",
      "count": 50
    },
    {
      "term": "DIZZINESS",
      "count": 45
    },
    {
      "term": "DENTAL CARIES",
      "count": 44
    },
    {
      "term": "DRUG DEPENDENCE",
      "count": 41
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 38
    },
    {
      "term": "PRODUCT SOLUBILITY ABNORMAL",
      "count": 38
    },
    {
      "term": "INSOMNIA",
      "count": 33
    },
    {
      "term": "TOOTH LOSS",
      "count": 32
    },
    {
      "term": "DIARRHOEA",
      "count": 31
    },
    {
      "term": "OVERDOSE",
      "count": 30
    },
    {
      "term": "CHILLS",
      "count": 29
    },
    {
      "term": "DYSPNOEA",
      "count": 29
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 29
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 28
    },
    {
      "term": "FATIGUE",
      "count": 26
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 26
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 25
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 25
    },
    {
      "term": "SOMNOLENCE",
      "count": 24
    },
    {
      "term": "TREMOR",
      "count": 24
    },
    {
      "term": "ASTHENIA",
      "count": 23
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 23
    },
    {
      "term": "CONSTIPATION",
      "count": 23
    },
    {
      "term": "ILLNESS",
      "count": 22
    },
    {
      "term": "RHINORRHOEA",
      "count": 22
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 21
    },
    {
      "term": "TOOTH FRACTURE",
      "count": 21
    },
    {
      "term": "RASH",
      "count": 20
    },
    {
      "term": "RESTLESSNESS",
      "count": 20
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 19
    },
    {
      "term": "PRODUCT DOSE OMISSION ISSUE",
      "count": 19
    },
    {
      "term": "PRODUCT PACKAGING QUANTITY ISSUE",
      "count": 19
    },
    {
      "term": "DRUG USE DISORDER",
      "count": 18
    },
    {
      "term": "DEPRESSION",
      "count": 17
    },
    {
      "term": "MYALGIA",
      "count": 17
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 16
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 16
    },
    {
      "term": "ARTHRALGIA",
      "count": 15
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 15
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 15
    },
    {
      "term": "RESTLESS LEGS SYNDROME",
      "count": 15
    },
    {
      "term": "SEROTONIN SYNDROME",
      "count": 15
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 14
    },
    {
      "term": "DEATH",
      "count": 14
    },
    {
      "term": "DRUG INTERACTION",
      "count": 14
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 14
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 14
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 13
    },
    {
      "term": "PRODUCT PHYSICAL ISSUE",
      "count": 13
    },
    {
      "term": "PRURITUS",
      "count": 13
    },
    {
      "term": "STOMATITIS",
      "count": 13
    },
    {
      "term": "VISION BLURRED",
      "count": 13
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 13
    },
    {
      "term": "AGITATION",
      "count": 12
    },
    {
      "term": "DECREASED APPETITE",
      "count": 12
    },
    {
      "term": "DEPRESSED LEVEL OF CONSCIOUSNESS",
      "count": 12
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 12
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 12
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 12
    },
    {
      "term": "PRODUCT DISPENSING ERROR",
      "count": 12
    },
    {
      "term": "PRODUCT TASTE ABNORMAL",
      "count": 12
    },
    {
      "term": "BACK PAIN",
      "count": 11
    },
    {
      "term": "DELIRIUM",
      "count": 11
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 11
    },
    {
      "term": "DRY MOUTH",
      "count": 11
    },
    {
      "term": "HEART RATE INCREASED",
      "count": 11
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 11
    },
    {
      "term": "IRRITABILITY",
      "count": 11
    },
    {
      "term": "LETHARGY",
      "count": 11
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 11
    },
    {
      "term": "MENTAL STATUS CHANGES",
      "count": 11
    },
    {
      "term": "ORAL DISCOMFORT",
      "count": 11
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 11
    },
    {
      "term": "PYREXIA",
      "count": 11
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 11
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 11
    },
    {
      "term": "TOOTH DISORDER",
      "count": 11
    },
    {
      "term": "UNDERDOSE",
      "count": 11
    },
    {
      "term": "ACCIDENTAL EXPOSURE TO PRODUCT BY CHILD",
      "count": 10
    },
    {
      "term": "CHEST PAIN",
      "count": 10
    },
    {
      "term": "COLD SWEAT",
      "count": 10
    },
    {
      "term": "DRUG DIVERSION",
      "count": 10
    },
    {
      "term": "FALL",
      "count": 10
    },
    {
      "term": "HYPERTENSION",
      "count": 10
    }
  ]
}