{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG DEPENDENCE",
      "count": 10065
    },
    {
      "term": "OVERDOSE",
      "count": 5942
    },
    {
      "term": "PAIN",
      "count": 3714
    },
    {
      "term": "DRUG ABUSE",
      "count": 2995
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME",
      "count": 2624
    },
    {
      "term": "NAUSEA",
      "count": 2576
    },
    {
      "term": "DEPENDENCE",
      "count": 2543
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2502
    },
    {
      "term": "EMOTIONAL DISTRESS",
      "count": 2475
    },
    {
      "term": "DEATH",
      "count": 2405
    },
    {
      "term": "FOETAL EXPOSURE DURING PREGNANCY",
      "count": 2210
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 2096
    },
    {
      "term": "ANXIETY",
      "count": 2095
    },
    {
      "term": "VOMITING",
      "count": 1880
    },
    {
      "term": "DRUG WITHDRAWAL SYNDROME NEONATAL",
      "count": 1822
    },
    {
      "term": "MATERNAL EXPOSURE DURING PREGNANCY",
      "count": 1597
    },
    {
      "term": "PRODUCT ADHESION ISSUE",
      "count": 1562
    },
    {
      "term": "HEADACHE",
      "count": 1540
    },
    {
      "term": "OFF LABEL USE",
      "count": 1450
    },
    {
      "term": "DEPRESSION",
      "count": 1403
    },
    {
      "term": "DIZZINESS",
      "count": 1190
    },
    {
      "term": "SOMNOLENCE",
      "count": 1130
    },
    {
      "term": "WITHDRAWAL SYNDROME",
      "count": 1117
    },
    {
      "term": "DIARRHOEA",
      "count": 1091
    },
    {
      "term": "DRUG INTERACTION",
      "count": 1083
    },
    {
      "term": "FATIGUE",
      "count": 1079
    },
    {
      "term": "DYSPNOEA",
      "count": 1044
    },
    {
      "term": "DEVELOPMENTAL DELAY",
      "count": 1036
    },
    {
      "term": "LEARNING DISABILITY",
      "count": 1003
    },
    {
      "term": "MALAISE",
      "count": 975
    },
    {
      "term": "INSOMNIA",
      "count": 964
    },
    {
      "term": "WRONG TECHNIQUE IN PRODUCT USAGE PROCESS",
      "count": 952
    },
    {
      "term": "ASTHENIA",
      "count": 924
    },
    {
      "term": "FALL",
      "count": 881
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 873
    },
    {
      "term": "ARTHRALGIA",
      "count": 798
    },
    {
      "term": "PRURITUS",
      "count": 758
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 745
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 734
    },
    {
      "term": "CONSTIPATION",
      "count": 704
    },
    {
      "term": "PRODUCT SUBSTITUTION ISSUE",
      "count": 674
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 673
    },
    {
      "term": "SUBSTANCE ABUSE",
      "count": 672
    },
    {
      "term": "RASH",
      "count": 668
    },
    {
      "term": "INTENTIONAL PRODUCT MISUSE",
      "count": 656
    },
    {
      "term": "DECREASED APPETITE",
      "count": 635
    },
    {
      "term": "PYREXIA",
      "count": 630
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 625
    },
    {
      "term": "DISABILITY",
      "count": 621
    },
    {
      "term": "PRODUCT SOLUBILITY ABNORMAL",
      "count": 616
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 615
    },
    {
      "term": "MENTAL DISORDER",
      "count": 606
    },
    {
      "term": "COMA",
      "count": 596
    },
    {
      "term": "PNEUMONIA",
      "count": 593
    },
    {
      "term": "INJURY",
      "count": 592
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 589
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 555
    },
    {
      "term": "SUICIDAL IDEATION",
      "count": 541
    },
    {
      "term": "PRODUCT QUALITY ISSUE",
      "count": 535
    },
    {
      "term": "TACHYCARDIA",
      "count": 535
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 524
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 524
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 516
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 508
    },
    {
      "term": "EXPOSURE DURING PREGNANCY",
      "count": 506
    },
    {
      "term": "DRUG USE DISORDER",
      "count": 500
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 484
    },
    {
      "term": "MUSCLE SPASMS",
      "count": 476
    },
    {
      "term": "HYPERTENSION",
      "count": 474
    },
    {
      "term": "PARAESTHESIA",
      "count": 468
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 464
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 460
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 460
    },
    {
      "term": "ORAL ADMINISTRATION COMPLICATION",
      "count": 453
    },
    {
      "term": "CHILLS",
      "count": 451
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 446
    },
    {
      "term": "DENTAL CARIES",
      "count": 445
    },
    {
      "term": "MYALGIA",
      "count": 441
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 440
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 440
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 437
    },
    {
      "term": "AGITATION",
      "count": 431
    },
    {
      "term": "SEPSIS",
      "count": 429
    },
    {
      "term": "STOMATITIS",
      "count": 428
    },
    {
      "term": "CARDIAC DISORDER",
      "count": 426
    },
    {
      "term": "GASTROOESOPHAGEAL REFLUX DISEASE",
      "count": 425
    },
    {
      "term": "DRY MOUTH",
      "count": 420
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 415
    },
    {
      "term": "NO ADVERSE EVENT",
      "count": 410
    },
    {
      "term": "TREMOR",
      "count": 407
    },
    {
      "term": "COMPLETED SUICIDE",
      "count": 393
    },
    {
      "term": "MIGRAINE",
      "count": 393
    },
    {
      "term": "SLEEP DISORDER",
      "count": 392
    },
    {
      "term": "HALLUCINATION",
      "count": 383
    },
    {
      "term": "SUICIDE ATTEMPT",
      "count": 382
    },
    {
      "term": "ROAD TRAFFIC ACCIDENT",
      "count": 380
    },
    {
      "term": "BACK PAIN",
      "count": 374
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 371
    },
    {
      "term": "COUGH",
      "count": 370
    },
    {
      "term": "SEIZURE",
      "count": 368
    }
  ]
}