{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 704
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 505
    },
    {
      "term": "PYREXIA",
      "count": 444
    },
    {
      "term": "NEUTROPENIA",
      "count": 382
    },
    {
      "term": "DEATH",
      "count": 364
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 334
    },
    {
      "term": "HODGKIN^S DISEASE",
      "count": 312
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 293
    },
    {
      "term": "ANAEMIA",
      "count": 291
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 287
    },
    {
      "term": "DIARRHOEA",
      "count": 274
    },
    {
      "term": "NAUSEA",
      "count": 270
    },
    {
      "term": "PNEUMONIA",
      "count": 240
    },
    {
      "term": "VOMITING",
      "count": 224
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 223
    },
    {
      "term": "FATIGUE",
      "count": 196
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 173
    },
    {
      "term": "SEPSIS",
      "count": 170
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 169
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 162
    },
    {
      "term": "ASTHENIA",
      "count": 152
    },
    {
      "term": "DYSPNOEA",
      "count": 144
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 144
    },
    {
      "term": "HYPOTENSION",
      "count": 135
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 129
    },
    {
      "term": "RASH",
      "count": 128
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 123
    },
    {
      "term": "INFECTION",
      "count": 122
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 120
    },
    {
      "term": "LEUKOPENIA",
      "count": 117
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 115
    },
    {
      "term": "DECREASED APPETITE",
      "count": 112
    },
    {
      "term": "DEHYDRATION",
      "count": 111
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 109
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 108
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 107
    },
    {
      "term": "PANCYTOPENIA",
      "count": 106
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 106
    },
    {
      "term": "COUGH",
      "count": 102
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 99
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 98
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 96
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 93
    },
    {
      "term": "PERIPHERAL SENSORY NEUROPATHY",
      "count": 91
    },
    {
      "term": "MALAISE",
      "count": 86
    },
    {
      "term": "COVID-19",
      "count": 84
    },
    {
      "term": "CONSTIPATION",
      "count": 81
    },
    {
      "term": "PNEUMONITIS",
      "count": 80
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 79
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 76
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 76
    },
    {
      "term": "CHILLS",
      "count": 75
    },
    {
      "term": "TACHYCARDIA",
      "count": 73
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 69
    },
    {
      "term": "HEADACHE",
      "count": 67
    },
    {
      "term": "PAIN",
      "count": 65
    },
    {
      "term": "COLITIS",
      "count": 63
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 63
    },
    {
      "term": "HODGKIN^S DISEASE RECURRENT",
      "count": 63
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 62
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 61
    },
    {
      "term": "PRURITUS",
      "count": 61
    },
    {
      "term": "BLOOD LACTATE DEHYDROGENASE INCREASED",
      "count": 59
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 58
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 56
    },
    {
      "term": "HODGKIN^S DISEASE REFRACTORY",
      "count": 54
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 53
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 53
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 53
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 51
    },
    {
      "term": "LYMPHOPENIA",
      "count": 51
    },
    {
      "term": "CYTOPENIA",
      "count": 49
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 49
    },
    {
      "term": "STOMATITIS",
      "count": 48
    },
    {
      "term": "BLINDNESS",
      "count": 47
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 47
    },
    {
      "term": "DIZZINESS",
      "count": 47
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 47
    },
    {
      "term": "GAMMA-GLUTAMYLTRANSFERASE INCREASED",
      "count": 46
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 45
    },
    {
      "term": "CYTOMEGALOVIRUS CHORIORETINITIS",
      "count": 45
    },
    {
      "term": "ERYTHEMA",
      "count": 45
    },
    {
      "term": "HERPES ZOSTER",
      "count": 45
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 44
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 44
    },
    {
      "term": "HOSPITALISATION",
      "count": 43
    },
    {
      "term": "ADVERSE EVENT",
      "count": 42
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 42
    },
    {
      "term": "CELLULITIS",
      "count": 41
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 41
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 41
    },
    {
      "term": "PERIPHERAL T-CELL LYMPHOMA UNSPECIFIED",
      "count": 41
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 41
    },
    {
      "term": "ARTHRALGIA",
      "count": 40
    },
    {
      "term": "BACK PAIN",
      "count": 39
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 39
    },
    {
      "term": "PARAESTHESIA",
      "count": 38
    },
    {
      "term": "ANAPHYLACTIC REACTION",
      "count": 37
    },
    {
      "term": "FALL",
      "count": 36
    },
    {
      "term": "FEBRILE BONE MARROW APLASIA",
      "count": 36
    }
  ]
}