{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "PLASMA CELL MYELOMA",
      "count": 5209
    },
    {
      "term": "OFF LABEL USE",
      "count": 3116
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 2259
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 1834
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1783
    },
    {
      "term": "PNEUMONIA",
      "count": 1616
    },
    {
      "term": "DEATH",
      "count": 1570
    },
    {
      "term": "DIARRHOEA",
      "count": 1427
    },
    {
      "term": "NEUTROPENIA",
      "count": 1418
    },
    {
      "term": "FATIGUE",
      "count": 1205
    },
    {
      "term": "ANAEMIA",
      "count": 1168
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 1057
    },
    {
      "term": "PYREXIA",
      "count": 993
    },
    {
      "term": "NAUSEA",
      "count": 939
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 910
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 862
    },
    {
      "term": "SEPSIS",
      "count": 810
    },
    {
      "term": "INFECTION",
      "count": 799
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 758
    },
    {
      "term": "INTENTIONAL PRODUCT USE ISSUE",
      "count": 747
    },
    {
      "term": "PLASMA CELL MYELOMA RECURRENT",
      "count": 650
    },
    {
      "term": "PANCYTOPENIA",
      "count": 643
    },
    {
      "term": "DYSPNOEA",
      "count": 616
    },
    {
      "term": "RASH",
      "count": 599
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 598
    },
    {
      "term": "VOMITING",
      "count": 577
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 575
    },
    {
      "term": "ASTHENIA",
      "count": 557
    },
    {
      "term": "CONSTIPATION",
      "count": 548
    },
    {
      "term": "COVID-19",
      "count": 513
    },
    {
      "term": "PLASMA CELL MYELOMA REFRACTORY",
      "count": 497
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 457
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 455
    },
    {
      "term": "POLYNEUROPATHY",
      "count": 430
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 427
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 425
    },
    {
      "term": "HYPOTENSION",
      "count": 424
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 407
    },
    {
      "term": "DIZZINESS",
      "count": 404
    },
    {
      "term": "DECREASED APPETITE",
      "count": 402
    },
    {
      "term": "RENAL FAILURE",
      "count": 390
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 381
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 377
    },
    {
      "term": "UNEVALUABLE EVENT",
      "count": 376
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 342
    },
    {
      "term": "LEUKOPENIA",
      "count": 329
    },
    {
      "term": "PAIN",
      "count": 318
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 317
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 314
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 314
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 312
    },
    {
      "term": "FALL",
      "count": 303
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 299
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 290
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 289
    },
    {
      "term": "SYNCOPE",
      "count": 289
    },
    {
      "term": "HERPES ZOSTER",
      "count": 287
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 285
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 283
    },
    {
      "term": "DEHYDRATION",
      "count": 282
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 278
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 263
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 263
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 260
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 254
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 254
    },
    {
      "term": "CYTOPENIA",
      "count": 253
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 251
    },
    {
      "term": "COUGH",
      "count": 249
    },
    {
      "term": "HYPERTENSION",
      "count": 249
    },
    {
      "term": "BACK PAIN",
      "count": 246
    },
    {
      "term": "HEADACHE",
      "count": 243
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 241
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 239
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 237
    },
    {
      "term": "INSOMNIA",
      "count": 236
    },
    {
      "term": "THERAPEUTIC RESPONSE DECREASED",
      "count": 235
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 229
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 216
    },
    {
      "term": "MALAISE",
      "count": 216
    },
    {
      "term": "PERIPHERAL SENSORY NEUROPATHY",
      "count": 216
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 211
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 209
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 200
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 199
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 197
    },
    {
      "term": "PARAESTHESIA",
      "count": 197
    },
    {
      "term": "LYMPHOPENIA",
      "count": 196
    },
    {
      "term": "GASTROINTESTINAL TOXICITY",
      "count": 192
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 192
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 191
    },
    {
      "term": "PLASMACYTOMA",
      "count": 190
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 190
    },
    {
      "term": "CHILLS",
      "count": 189
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 189
    },
    {
      "term": "NEUROTOXICITY",
      "count": 188
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 187
    },
    {
      "term": "ORTHOSTATIC HYPOTENSION",
      "count": 187
    },
    {
      "term": "PRURITUS",
      "count": 187
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 186
    }
  ]
}