{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA RECURRENT",
      "count": 594
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 489
    },
    {
      "term": "DEATH",
      "count": 312
    },
    {
      "term": "PYREXIA",
      "count": 304
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 262
    },
    {
      "term": "OFF LABEL USE",
      "count": 250
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 212
    },
    {
      "term": "NEUROTOXICITY",
      "count": 208
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 189
    },
    {
      "term": "NEUTROPENIA",
      "count": 178
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 147
    },
    {
      "term": "INFECTION",
      "count": 146
    },
    {
      "term": "HEADACHE",
      "count": 123
    },
    {
      "term": "SEPSIS",
      "count": 121
    },
    {
      "term": "PNEUMONIA",
      "count": 117
    },
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA",
      "count": 113
    },
    {
      "term": "SEIZURE",
      "count": 105
    },
    {
      "term": "ANAEMIA",
      "count": 104
    },
    {
      "term": "IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME",
      "count": 104
    },
    {
      "term": "LEUKAEMIC INFILTRATION EXTRAMEDULLARY",
      "count": 103
    },
    {
      "term": "B-CELL TYPE ACUTE LEUKAEMIA",
      "count": 102
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE",
      "count": 92
    },
    {
      "term": "TREMOR",
      "count": 88
    },
    {
      "term": "B PRECURSOR TYPE ACUTE LEUKAEMIA",
      "count": 87
    },
    {
      "term": "ENCEPHALOPATHY",
      "count": 85
    },
    {
      "term": "PANCYTOPENIA",
      "count": 82
    },
    {
      "term": "CENTRAL NERVOUS SYSTEM LEUKAEMIA",
      "count": 80
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 79
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 76
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 75
    },
    {
      "term": "MINIMAL RESIDUAL DISEASE",
      "count": 74
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 73
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 72
    },
    {
      "term": "CYTOPENIA",
      "count": 69
    },
    {
      "term": "VENOOCCLUSIVE LIVER DISEASE",
      "count": 69
    },
    {
      "term": "VOMITING",
      "count": 67
    },
    {
      "term": "CHRONIC GRAFT VERSUS HOST DISEASE",
      "count": 66
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 63
    },
    {
      "term": "NAUSEA",
      "count": 61
    },
    {
      "term": "COVID-19",
      "count": 60
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 60
    },
    {
      "term": "NERVOUS SYSTEM DISORDER",
      "count": 59
    },
    {
      "term": "HYPOTENSION",
      "count": 58
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 56
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 55
    },
    {
      "term": "HYPERTENSION",
      "count": 55
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 55
    },
    {
      "term": "APHASIA",
      "count": 54
    },
    {
      "term": "RASH",
      "count": 54
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 50
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 50
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 49
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 49
    },
    {
      "term": "DIARRHOEA",
      "count": 48
    },
    {
      "term": "HYPERGLYCAEMIA",
      "count": 48
    },
    {
      "term": "STOMATITIS",
      "count": 48
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 47
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 47
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 46
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 46
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 45
    },
    {
      "term": "FATIGUE",
      "count": 44
    },
    {
      "term": "DYSPNOEA",
      "count": 43
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 43
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 42
    },
    {
      "term": "TRANSFORMATION TO ACUTE MYELOID LEUKAEMIA",
      "count": 42
    },
    {
      "term": "ACUTE LYMPHOCYTIC LEUKAEMIA REFRACTORY",
      "count": 41
    },
    {
      "term": "NEOPLASM PROGRESSION",
      "count": 41
    },
    {
      "term": "ACUTE GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 40
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 40
    },
    {
      "term": "DEVICE RELATED INFECTION",
      "count": 40
    },
    {
      "term": "HYPOXIA",
      "count": 40
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 40
    },
    {
      "term": "DYSARTHRIA",
      "count": 39
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN SKIN",
      "count": 39
    },
    {
      "term": "LEUKOPENIA",
      "count": 39
    },
    {
      "term": "ASTHENIA",
      "count": 38
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 38
    },
    {
      "term": "VENOOCCLUSIVE DISEASE",
      "count": 38
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 38
    },
    {
      "term": "BLOOD BILIRUBIN INCREASED",
      "count": 36
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 35
    },
    {
      "term": "PANCREATITIS",
      "count": 35
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 35
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 35
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 34
    },
    {
      "term": "ADVERSE EVENT",
      "count": 33
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE IN GASTROINTESTINAL TRACT",
      "count": 33
    },
    {
      "term": "LEUKAEMIA RECURRENT",
      "count": 33
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 33
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 33
    },
    {
      "term": "HYPOGAMMAGLOBULINAEMIA",
      "count": 32
    },
    {
      "term": "BACTERAEMIA",
      "count": 31
    },
    {
      "term": "CHILLS",
      "count": 31
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 31
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 31
    },
    {
      "term": "DRUG EFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 30
    },
    {
      "term": "DELIRIUM",
      "count": 29
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 29
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 29
    }
  ]
}