{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FATIGUE",
      "count": 850
    },
    {
      "term": "DEATH",
      "count": 617
    },
    {
      "term": "PROSTATIC SPECIFIC ANTIGEN INCREASED",
      "count": 584
    },
    {
      "term": "PROSTATE CANCER",
      "count": 517
    },
    {
      "term": "HOT FLUSH",
      "count": 505
    },
    {
      "term": "ASTHENIA",
      "count": 489
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 453
    },
    {
      "term": "NAUSEA",
      "count": 359
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 351
    },
    {
      "term": "DIARRHOEA",
      "count": 325
    },
    {
      "term": "DIZZINESS",
      "count": 321
    },
    {
      "term": "DYSPNOEA",
      "count": 310
    },
    {
      "term": "OFF LABEL USE",
      "count": 299
    },
    {
      "term": "DECREASED APPETITE",
      "count": 298
    },
    {
      "term": "ANAEMIA",
      "count": 286
    },
    {
      "term": "FALL",
      "count": 254
    },
    {
      "term": "METASTASES TO BONE",
      "count": 253
    },
    {
      "term": "PNEUMONIA",
      "count": 249
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 248
    },
    {
      "term": "PAIN",
      "count": 222
    },
    {
      "term": "CONSTIPATION",
      "count": 220
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 217
    },
    {
      "term": "DRUG INTERACTION",
      "count": 215
    },
    {
      "term": "ARTHRALGIA",
      "count": 210
    },
    {
      "term": "BACK PAIN",
      "count": 203
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 203
    },
    {
      "term": "MALAISE",
      "count": 201
    },
    {
      "term": "PYREXIA",
      "count": 177
    },
    {
      "term": "PROSTATE CANCER METASTATIC",
      "count": 174
    },
    {
      "term": "HAEMATURIA",
      "count": 171
    },
    {
      "term": "HYPERTENSION",
      "count": 167
    },
    {
      "term": "HEADACHE",
      "count": 166
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 162
    },
    {
      "term": "INSOMNIA",
      "count": 161
    },
    {
      "term": "VOMITING",
      "count": 155
    },
    {
      "term": "HYPOTENSION",
      "count": 151
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 149
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 142
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 138
    },
    {
      "term": "RASH",
      "count": 135
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 134
    },
    {
      "term": "GAIT DISTURBANCE",
      "count": 132
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 124
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 114
    },
    {
      "term": "BONE PAIN",
      "count": 111
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 106
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 106
    },
    {
      "term": "OSTEONECROSIS OF JAW",
      "count": 105
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 105
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 104
    },
    {
      "term": "URINARY RETENTION",
      "count": 104
    },
    {
      "term": "DEHYDRATION",
      "count": 102
    },
    {
      "term": "DEMENTIA ALZHEIMER^S TYPE",
      "count": 102
    },
    {
      "term": "CHEST PAIN",
      "count": 100
    },
    {
      "term": "NEUTROPENIA",
      "count": 100
    },
    {
      "term": "MEMORY IMPAIRMENT",
      "count": 98
    },
    {
      "term": "SOMNOLENCE",
      "count": 98
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 97
    },
    {
      "term": "SYNCOPE",
      "count": 97
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 96
    },
    {
      "term": "RENAL FAILURE",
      "count": 96
    },
    {
      "term": "ELECTROCARDIOGRAM QT PROLONGED",
      "count": 94
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 94
    },
    {
      "term": "HYPERHIDROSIS",
      "count": 94
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 92
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 91
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 91
    },
    {
      "term": "MYALGIA",
      "count": 91
    },
    {
      "term": "PRURITUS",
      "count": 86
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 85
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 84
    },
    {
      "term": "GYNAECOMASTIA",
      "count": 84
    },
    {
      "term": "MYOCARDIAL INFARCTION",
      "count": 82
    },
    {
      "term": "POLLAKIURIA",
      "count": 82
    },
    {
      "term": "COUGH",
      "count": 80
    },
    {
      "term": "METASTASES TO LYMPH NODES",
      "count": 78
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 78
    },
    {
      "term": "NEUROPATHY PERIPHERAL",
      "count": 76
    },
    {
      "term": "RENAL DISORDER",
      "count": 75
    },
    {
      "term": "ABDOMINAL DISCOMFORT",
      "count": 74
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 74
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 72
    },
    {
      "term": "HAEMORRHAGE",
      "count": 72
    },
    {
      "term": "METASTASES TO LUNG",
      "count": 71
    },
    {
      "term": "HORMONE-REFRACTORY PROSTATE CANCER",
      "count": 70
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 70
    },
    {
      "term": "HOSPITALISATION",
      "count": 68
    },
    {
      "term": "SEPSIS",
      "count": 68
    },
    {
      "term": "DEPRESSION",
      "count": 67
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 67
    },
    {
      "term": "ABDOMINAL PAIN UPPER",
      "count": 66
    },
    {
      "term": "DYSPHAGIA",
      "count": 66
    },
    {
      "term": "DYSURIA",
      "count": 66
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 65
    },
    {
      "term": "HYPOCALCAEMIA",
      "count": 65
    },
    {
      "term": "UNDERDOSE",
      "count": 65
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 64
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 63
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 63
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 62
    }
  ]
}