{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "DRUG INEFFECTIVE",
      "count": 163
    },
    {
      "term": "ARTHRALGIA",
      "count": 146
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 141
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 140
    },
    {
      "term": "DRUG HYPERSENSITIVITY",
      "count": 134
    },
    {
      "term": "JOINT SWELLING",
      "count": 128
    },
    {
      "term": "MUSCULOSKELETAL STIFFNESS",
      "count": 128
    },
    {
      "term": "INFECTION",
      "count": 126
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 122
    },
    {
      "term": "HEPATOTOXICITY",
      "count": 118
    },
    {
      "term": "MUSCULOSKELETAL PAIN",
      "count": 117
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 117
    },
    {
      "term": "GASTROINTESTINAL TOXICITY",
      "count": 116
    },
    {
      "term": "JOINT INJURY",
      "count": 114
    },
    {
      "term": "PULMONARY TOXICITY",
      "count": 114
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 112
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 112
    },
    {
      "term": "ARTHROPATHY",
      "count": 109
    },
    {
      "term": "C-REACTIVE PROTEIN ABNORMAL",
      "count": 106
    },
    {
      "term": "JOINT STIFFNESS",
      "count": 104
    },
    {
      "term": "DRUG INTOLERANCE",
      "count": 102
    },
    {
      "term": "OFF LABEL USE",
      "count": 88
    },
    {
      "term": "NAUSEA",
      "count": 73
    },
    {
      "term": "RASH",
      "count": 69
    },
    {
      "term": "FATIGUE",
      "count": 59
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 59
    },
    {
      "term": "PAIN",
      "count": 58
    },
    {
      "term": "DIARRHOEA",
      "count": 57
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 57
    },
    {
      "term": "DYSPNOEA",
      "count": 54
    },
    {
      "term": "HEADACHE",
      "count": 50
    },
    {
      "term": "INFLAMMATION",
      "count": 50
    },
    {
      "term": "BACK PAIN",
      "count": 49
    },
    {
      "term": "PYREXIA",
      "count": 48
    },
    {
      "term": "DIZZINESS",
      "count": 45
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 43
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT DECREASED",
      "count": 43
    },
    {
      "term": "CONTRAINDICATED PRODUCT ADMINISTERED",
      "count": 42
    },
    {
      "term": "ERYTHEMA",
      "count": 42
    },
    {
      "term": "PRURITUS",
      "count": 42
    },
    {
      "term": "MALAISE",
      "count": 39
    },
    {
      "term": "VOMITING",
      "count": 39
    },
    {
      "term": "CONSTIPATION",
      "count": 33
    },
    {
      "term": "PNEUMONIA",
      "count": 30
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 28
    },
    {
      "term": "WHEEZING",
      "count": 28
    },
    {
      "term": "ANAEMIA",
      "count": 27
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 27
    },
    {
      "term": "COUGH",
      "count": 27
    },
    {
      "term": "FEELING ABNORMAL",
      "count": 25
    },
    {
      "term": "HYPERSENSITIVITY",
      "count": 25
    },
    {
      "term": "MYALGIA",
      "count": 25
    },
    {
      "term": "OCULAR HYPERAEMIA",
      "count": 25
    },
    {
      "term": "SWELLING FACE",
      "count": 24
    },
    {
      "term": "HYPERTENSION",
      "count": 23
    },
    {
      "term": "VISUAL IMPAIRMENT",
      "count": 23
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 22
    },
    {
      "term": "NASOPHARYNGITIS",
      "count": 22
    },
    {
      "term": "SINUSITIS",
      "count": 22
    },
    {
      "term": "EYE IRRITATION",
      "count": 21
    },
    {
      "term": "BLISTER",
      "count": 20
    },
    {
      "term": "FIBROMYALGIA",
      "count": 20
    },
    {
      "term": "ARTHRITIS",
      "count": 19
    },
    {
      "term": "ASTHENIA",
      "count": 19
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 19
    },
    {
      "term": "CHEST DISCOMFORT",
      "count": 19
    },
    {
      "term": "INSOMNIA",
      "count": 19
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 19
    },
    {
      "term": "RASH MACULO-PAPULAR",
      "count": 19
    },
    {
      "term": "SKIN ULCER",
      "count": 19
    },
    {
      "term": "SWELLING",
      "count": 19
    },
    {
      "term": "EYE PAIN",
      "count": 18
    },
    {
      "term": "JOINT RANGE OF MOTION DECREASED",
      "count": 18
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 18
    },
    {
      "term": "TOXIC ANTERIOR SEGMENT SYNDROME",
      "count": 18
    },
    {
      "term": "DEATH",
      "count": 17
    },
    {
      "term": "DECREASED APPETITE",
      "count": 17
    },
    {
      "term": "DRY EYE",
      "count": 17
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 17
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 17
    },
    {
      "term": "RASH PRURITIC",
      "count": 17
    },
    {
      "term": "CONJUNCTIVITIS",
      "count": 16
    },
    {
      "term": "DRY MOUTH",
      "count": 16
    },
    {
      "term": "FALL",
      "count": 16
    },
    {
      "term": "INFUSION RELATED REACTION",
      "count": 16
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 16
    },
    {
      "term": "LIVER DISORDER",
      "count": 16
    },
    {
      "term": "LUNG DISORDER",
      "count": 16
    },
    {
      "term": "ANXIETY",
      "count": 15
    },
    {
      "term": "FOLLICULITIS",
      "count": 15
    },
    {
      "term": "HALLUCINATION",
      "count": 15
    },
    {
      "term": "HYPOAESTHESIA",
      "count": 15
    },
    {
      "term": "INCORRECT DOSE ADMINISTERED",
      "count": 15
    },
    {
      "term": "PRODUCT PREPARATION ERROR",
      "count": 15
    },
    {
      "term": "PRODUCTIVE COUGH",
      "count": 15
    },
    {
      "term": "SOMNOLENCE",
      "count": 15
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 15
    },
    {
      "term": "ULCER",
      "count": 15
    },
    {
      "term": "UPPER RESPIRATORY TRACT INFECTION",
      "count": 15
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 15
    }
  ]
}