{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 909
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 831
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION",
      "count": 744
    },
    {
      "term": "TRANSPLANT REJECTION",
      "count": 693
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 480
    },
    {
      "term": "KIDNEY TRANSPLANT REJECTION",
      "count": 427
    },
    {
      "term": "PYREXIA",
      "count": 402
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 390
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 380
    },
    {
      "term": "DIARRHOEA",
      "count": 352
    },
    {
      "term": "POLYOMAVIRUS-ASSOCIATED NEPHROPATHY",
      "count": 347
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 347
    },
    {
      "term": "SEPSIS",
      "count": 338
    },
    {
      "term": "PNEUMONIA",
      "count": 332
    },
    {
      "term": "ANAEMIA",
      "count": 326
    },
    {
      "term": "THROMBOTIC MICROANGIOPATHY",
      "count": 326
    },
    {
      "term": "LEUKOPENIA",
      "count": 320
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 309
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 298
    },
    {
      "term": "NEUTROPENIA",
      "count": 286
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 270
    },
    {
      "term": "BK VIRUS INFECTION",
      "count": 260
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 260
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 243
    },
    {
      "term": "CYTOMEGALOVIRUS VIRAEMIA",
      "count": 238
    },
    {
      "term": "COMPLICATIONS OF TRANSPLANTED KIDNEY",
      "count": 232
    },
    {
      "term": "POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER",
      "count": 232
    },
    {
      "term": "PANCYTOPENIA",
      "count": 230
    },
    {
      "term": "DRUG INTERACTION",
      "count": 229
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 226
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 214
    },
    {
      "term": "COVID-19",
      "count": 187
    },
    {
      "term": "INFECTION",
      "count": 182
    },
    {
      "term": "RENAL TUBULAR NECROSIS",
      "count": 182
    },
    {
      "term": "KAPOSI^S SARCOMA",
      "count": 181
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 178
    },
    {
      "term": "MUCORMYCOSIS",
      "count": 178
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 176
    },
    {
      "term": "RENAL FAILURE",
      "count": 170
    },
    {
      "term": "EPSTEIN-BARR VIRUS INFECTION",
      "count": 169
    },
    {
      "term": "NEPHROPATHY TOXIC",
      "count": 166
    },
    {
      "term": "TUBULOINTERSTITIAL NEPHRITIS",
      "count": 163
    },
    {
      "term": "DRUG RESISTANCE",
      "count": 149
    },
    {
      "term": "HYPERTENSION",
      "count": 144
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 139
    },
    {
      "term": "DELAYED GRAFT FUNCTION",
      "count": 138
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 137
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 135
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 134
    },
    {
      "term": "NAUSEA",
      "count": 134
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 132
    },
    {
      "term": "ENTEROCOCCAL INFECTION",
      "count": 131
    },
    {
      "term": "POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME",
      "count": 131
    },
    {
      "term": "IMMUNOSUPPRESSANT DRUG LEVEL INCREASED",
      "count": 129
    },
    {
      "term": "VOMITING",
      "count": 127
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 124
    },
    {
      "term": "TRANSPLANT DYSFUNCTION",
      "count": 123
    },
    {
      "term": "CYTOMEGALOVIRUS INFECTION REACTIVATION",
      "count": 117
    },
    {
      "term": "ESCHERICHIA INFECTION",
      "count": 112
    },
    {
      "term": "DEATH",
      "count": 111
    },
    {
      "term": "DYSPNOEA",
      "count": 111
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 109
    },
    {
      "term": "PARVOVIRUS B19 INFECTION",
      "count": 109
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 108
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 108
    },
    {
      "term": "BACTERIAL INFECTION",
      "count": 107
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 107
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 107
    },
    {
      "term": "STRONGYLOIDIASIS",
      "count": 107
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 106
    },
    {
      "term": "PROTEINURIA",
      "count": 103
    },
    {
      "term": "FOCAL SEGMENTAL GLOMERULOSCLEROSIS",
      "count": 99
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 99
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 98
    },
    {
      "term": "DISSEMINATED INTRAVASCULAR COAGULATION",
      "count": 95
    },
    {
      "term": "KLEBSIELLA INFECTION",
      "count": 95
    },
    {
      "term": "TRANSPLANT FAILURE",
      "count": 95
    },
    {
      "term": "BACTERAEMIA",
      "count": 94
    },
    {
      "term": "HYPOTENSION",
      "count": 94
    },
    {
      "term": "ASCITES",
      "count": 92
    },
    {
      "term": "HYPERAMMONAEMIA",
      "count": 91
    },
    {
      "term": "CHRONIC ALLOGRAFT NEPHROPATHY",
      "count": 88
    },
    {
      "term": "CYTOMEGALOVIRUS COLITIS",
      "count": 87
    },
    {
      "term": "HYDRONEPHROSIS",
      "count": 87
    },
    {
      "term": "BLOOD GLUCOSE INCREASED",
      "count": 84
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 84
    },
    {
      "term": "HERPES SIMPLEX",
      "count": 84
    },
    {
      "term": "BLOOD UREA INCREASED",
      "count": 83
    },
    {
      "term": "POLYOMAVIRUS VIRAEMIA",
      "count": 83
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 81
    },
    {
      "term": "NEUTROPHIL COUNT INCREASED",
      "count": 81
    },
    {
      "term": "HEADACHE",
      "count": 80
    },
    {
      "term": "HEPATIC FAILURE",
      "count": 80
    },
    {
      "term": "LIVER TRANSPLANT REJECTION",
      "count": 80
    },
    {
      "term": "ADENOVIRUS INFECTION",
      "count": 78
    },
    {
      "term": "LYMPHOPENIA",
      "count": 78
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 77
    },
    {
      "term": "PATHOGEN RESISTANCE",
      "count": 77
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 77
    },
    {
      "term": "GASTROINTESTINAL DISORDER",
      "count": 76
    }
  ]
}