{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "OFF LABEL USE",
      "count": 387
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 311
    },
    {
      "term": "COVID-19",
      "count": 173
    },
    {
      "term": "PULMONARY EMBOLISM",
      "count": 170
    },
    {
      "term": "PNEUMONIA",
      "count": 134
    },
    {
      "term": "RHEUMATOID ARTHRITIS",
      "count": 123
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 122
    },
    {
      "term": "DEATH",
      "count": 105
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 100
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 87
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 69
    },
    {
      "term": "COVID-19 PNEUMONIA",
      "count": 69
    },
    {
      "term": "HERPES ZOSTER",
      "count": 69
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 68
    },
    {
      "term": "HEADACHE",
      "count": 67
    },
    {
      "term": "NAUSEA",
      "count": 67
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 62
    },
    {
      "term": "DIARRHOEA",
      "count": 60
    },
    {
      "term": "LEUKOPENIA",
      "count": 59
    },
    {
      "term": "VOMITING",
      "count": 59
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 58
    },
    {
      "term": "ARTHRITIS",
      "count": 58
    },
    {
      "term": "DYSPNOEA",
      "count": 57
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 54
    },
    {
      "term": "HAEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS",
      "count": 50
    },
    {
      "term": "INFECTION",
      "count": 50
    },
    {
      "term": "SEPSIS",
      "count": 50
    },
    {
      "term": "FATIGUE",
      "count": 49
    },
    {
      "term": "PYREXIA",
      "count": 49
    },
    {
      "term": "COUGH",
      "count": 48
    },
    {
      "term": "WEIGHT INCREASED",
      "count": 48
    },
    {
      "term": "ARTHRALGIA",
      "count": 47
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 47
    },
    {
      "term": "STAPHYLOCOCCAL INFECTION",
      "count": 47
    },
    {
      "term": "RASH",
      "count": 44
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 44
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 43
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 42
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 41
    },
    {
      "term": "LIVER FUNCTION TEST INCREASED",
      "count": 40
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 40
    },
    {
      "term": "ACUTE RESPIRATORY FAILURE",
      "count": 38
    },
    {
      "term": "CARDIAC ARREST",
      "count": 38
    },
    {
      "term": "OXYGEN SATURATION DECREASED",
      "count": 38
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 37
    },
    {
      "term": "PAIN",
      "count": 37
    },
    {
      "term": "PNEUMONIA BACTERIAL",
      "count": 37
    },
    {
      "term": "HYPOXIA",
      "count": 36
    },
    {
      "term": "BLOOD FOLATE DECREASED",
      "count": 35
    },
    {
      "term": "LEUKOCYTOSIS",
      "count": 35
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 35
    },
    {
      "term": "LIMB DISCOMFORT",
      "count": 34
    },
    {
      "term": "ACUTE RESPIRATORY DISTRESS SYNDROME",
      "count": 33
    },
    {
      "term": "HYPOTENSION",
      "count": 33
    },
    {
      "term": "TACHYCARDIA",
      "count": 33
    },
    {
      "term": "ARTHROPATHY",
      "count": 32
    },
    {
      "term": "MASS",
      "count": 32
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 32
    },
    {
      "term": "FIBRIN D DIMER INCREASED",
      "count": 31
    },
    {
      "term": "CEREBROVASCULAR ACCIDENT",
      "count": 30
    },
    {
      "term": "HEPATITIS",
      "count": 30
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 30
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 29
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 28
    },
    {
      "term": "PNEUMOCYSTIS JIROVECII PNEUMONIA",
      "count": 28
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 27
    },
    {
      "term": "OSTEOARTHRITIS",
      "count": 27
    },
    {
      "term": "PERIPHERAL SWELLING",
      "count": 27
    },
    {
      "term": "ANAEMIA",
      "count": 26
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 26
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 26
    },
    {
      "term": "LUMBOSACRAL PLEXOPATHY",
      "count": 26
    },
    {
      "term": "LYMPHOPENIA",
      "count": 26
    },
    {
      "term": "NEUROGENIC BLADDER",
      "count": 26
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 26
    },
    {
      "term": "TRANSAMINASES INCREASED",
      "count": 26
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 25
    },
    {
      "term": "MALAISE",
      "count": 25
    },
    {
      "term": "PERINEAL RASH",
      "count": 25
    },
    {
      "term": "BLOOD TEST ABNORMAL",
      "count": 24
    },
    {
      "term": "BACTERAEMIA",
      "count": 23
    },
    {
      "term": "CHEST PAIN",
      "count": 23
    },
    {
      "term": "DIZZINESS",
      "count": 23
    },
    {
      "term": "DRUG INTERACTION",
      "count": 23
    },
    {
      "term": "THERAPY PARTIAL RESPONDER",
      "count": 23
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 22
    },
    {
      "term": "CANDIDA INFECTION",
      "count": 22
    },
    {
      "term": "PSEUDOMONAS INFECTION",
      "count": 22
    },
    {
      "term": "CARDIO-RESPIRATORY ARREST",
      "count": 21
    },
    {
      "term": "GASTROENTERITIS",
      "count": 21
    },
    {
      "term": "HYPERTENSION",
      "count": 21
    },
    {
      "term": "NEOPLASM MALIGNANT",
      "count": 21
    },
    {
      "term": "PRURITUS",
      "count": 21
    },
    {
      "term": "ACUTE MYOCARDIAL INFARCTION",
      "count": 20
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 20
    },
    {
      "term": "INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION",
      "count": 20
    },
    {
      "term": "LYMPHOCYTE COUNT DECREASED",
      "count": 20
    },
    {
      "term": "OVERDOSE",
      "count": 20
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 20
    },
    {
      "term": "RESPIRATORY TRACT INFECTION",
      "count": 20
    }
  ]
}