{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "RENAL IMPAIRMENT",
      "count": 129
    },
    {
      "term": "HYPERTENSION",
      "count": 119
    },
    {
      "term": "DIARRHOEA",
      "count": 111
    },
    {
      "term": "DECREASED APPETITE",
      "count": 104
    },
    {
      "term": "OFF LABEL USE",
      "count": 97
    },
    {
      "term": "NAUSEA",
      "count": 76
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 74
    },
    {
      "term": "MALAISE",
      "count": 72
    },
    {
      "term": "PYREXIA",
      "count": 71
    },
    {
      "term": "CEREBRAL INFARCTION",
      "count": 69
    },
    {
      "term": "INTERSTITIAL LUNG DISEASE",
      "count": 67
    },
    {
      "term": "ANAEMIA",
      "count": 64
    },
    {
      "term": "DEHYDRATION",
      "count": 61
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 58
    },
    {
      "term": "DRUG INTERACTION",
      "count": 55
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 55
    },
    {
      "term": "PNEUMONIA",
      "count": 55
    },
    {
      "term": "VOMITING",
      "count": 54
    },
    {
      "term": "DIZZINESS",
      "count": 53
    },
    {
      "term": "HEPATIC FUNCTION ABNORMAL",
      "count": 52
    },
    {
      "term": "HYPERKALAEMIA",
      "count": 49
    },
    {
      "term": "HYPOTENSION",
      "count": 41
    },
    {
      "term": "PROTEINURIA",
      "count": 40
    },
    {
      "term": "COVID-19",
      "count": 39
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 39
    },
    {
      "term": "FALL",
      "count": 38
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 37
    },
    {
      "term": "ALTERED STATE OF CONSCIOUSNESS",
      "count": 35
    },
    {
      "term": "CONSTIPATION",
      "count": 35
    },
    {
      "term": "PRURITUS",
      "count": 35
    },
    {
      "term": "RASH",
      "count": 34
    },
    {
      "term": "BLOOD PRESSURE DECREASED",
      "count": 33
    },
    {
      "term": "FATIGUE",
      "count": 33
    },
    {
      "term": "RENAL FAILURE",
      "count": 33
    },
    {
      "term": "HEADACHE",
      "count": 32
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 32
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 32
    },
    {
      "term": "DEATH",
      "count": 31
    },
    {
      "term": "HYPOTHYROIDISM",
      "count": 31
    },
    {
      "term": "LIVER DISORDER",
      "count": 31
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 30
    },
    {
      "term": "CHRONIC KIDNEY DISEASE",
      "count": 30
    },
    {
      "term": "LACTIC ACIDOSIS",
      "count": 30
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 30
    },
    {
      "term": "ARTHRALGIA",
      "count": 29
    },
    {
      "term": "BLOOD PRESSURE INCREASED",
      "count": 29
    },
    {
      "term": "DYSPNOEA",
      "count": 28
    },
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 28
    },
    {
      "term": "PALMAR-PLANTAR ERYTHRODYSAESTHESIA SYNDROME",
      "count": 28
    },
    {
      "term": "RHABDOMYOLYSIS",
      "count": 28
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 27
    },
    {
      "term": "OEDEMA",
      "count": 27
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 27
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 27
    },
    {
      "term": "LOSS OF CONSCIOUSNESS",
      "count": 26
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 25
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 24
    },
    {
      "term": "SEPSIS",
      "count": 23
    },
    {
      "term": "ALANINE AMINOTRANSFERASE INCREASED",
      "count": 22
    },
    {
      "term": "HYPOGLYCAEMIA",
      "count": 22
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 22
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 21
    },
    {
      "term": "ERYTHEMA",
      "count": 21
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 21
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 21
    },
    {
      "term": "ADRENAL INSUFFICIENCY",
      "count": 20
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 20
    },
    {
      "term": "DIABETES MELLITUS",
      "count": 20
    },
    {
      "term": "DRUG-INDUCED LIVER INJURY",
      "count": 20
    },
    {
      "term": "ASCITES",
      "count": 19
    },
    {
      "term": "BLOOD CREATINE PHOSPHOKINASE INCREASED",
      "count": 19
    },
    {
      "term": "BRADYCARDIA",
      "count": 19
    },
    {
      "term": "CARDIAC FAILURE CONGESTIVE",
      "count": 19
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 19
    },
    {
      "term": "ASTHENIA",
      "count": 18
    },
    {
      "term": "DRUG ERUPTION",
      "count": 18
    },
    {
      "term": "HYPONATRAEMIA",
      "count": 18
    },
    {
      "term": "NEPHROTIC SYNDROME",
      "count": 18
    },
    {
      "term": "OVERDOSE",
      "count": 18
    },
    {
      "term": "PANCYTOPENIA",
      "count": 18
    },
    {
      "term": "PNEUMONIA ASPIRATION",
      "count": 18
    },
    {
      "term": "PYELONEPHRITIS",
      "count": 18
    },
    {
      "term": "ASPARTATE AMINOTRANSFERASE INCREASED",
      "count": 17
    },
    {
      "term": "BACK PAIN",
      "count": 17
    },
    {
      "term": "CYTOKINE RELEASE SYNDROME",
      "count": 17
    },
    {
      "term": "PEMPHIGOID",
      "count": 17
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 17
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 17
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 17
    },
    {
      "term": "CARDIAC ARREST",
      "count": 16
    },
    {
      "term": "MUSCULAR WEAKNESS",
      "count": 16
    },
    {
      "term": "SHOCK",
      "count": 16
    },
    {
      "term": "STOMATITIS",
      "count": 16
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 15
    },
    {
      "term": "DRUG LEVEL INCREASED",
      "count": 15
    },
    {
      "term": "DYSPHAGIA",
      "count": 15
    },
    {
      "term": "GLOMERULAR FILTRATION RATE DECREASED",
      "count": 15
    },
    {
      "term": "PAIN IN EXTREMITY",
      "count": 15
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 15
    },
    {
      "term": "UNDERDOSE",
      "count": 15
    }
  ]
}