{
  "meta": {
    "disclaimer": "Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.",
    "terms": "https://open.fda.gov/terms/",
    "license": "https://open.fda.gov/license/",
    "last_updated": "2026-04-28"
  },
  "results": [
    {
      "term": "FEBRILE NEUTROPENIA",
      "count": 2087
    },
    {
      "term": "DEATH",
      "count": 1984
    },
    {
      "term": "OFF LABEL USE",
      "count": 1473
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA",
      "count": 1377
    },
    {
      "term": "NEUTROPENIA",
      "count": 1366
    },
    {
      "term": "MYELOSUPPRESSION",
      "count": 1358
    },
    {
      "term": "PNEUMONIA",
      "count": 1171
    },
    {
      "term": "PYREXIA",
      "count": 1043
    },
    {
      "term": "THROMBOCYTOPENIA",
      "count": 1022
    },
    {
      "term": "DRUG INEFFECTIVE",
      "count": 1000
    },
    {
      "term": "ANAEMIA",
      "count": 820
    },
    {
      "term": "SEPSIS",
      "count": 719
    },
    {
      "term": "INFECTION",
      "count": 713
    },
    {
      "term": "PANCYTOPENIA",
      "count": 653
    },
    {
      "term": "PLATELET COUNT DECREASED",
      "count": 594
    },
    {
      "term": "NAUSEA",
      "count": 497
    },
    {
      "term": "WHITE BLOOD CELL COUNT DECREASED",
      "count": 484
    },
    {
      "term": "DIARRHOEA",
      "count": 459
    },
    {
      "term": "CYTOPENIA",
      "count": 452
    },
    {
      "term": "ACUTE MYELOID LEUKAEMIA RECURRENT",
      "count": 446
    },
    {
      "term": "DISEASE PROGRESSION",
      "count": 443
    },
    {
      "term": "NEUTROPHIL COUNT DECREASED",
      "count": 432
    },
    {
      "term": "SEPTIC SHOCK",
      "count": 419
    },
    {
      "term": "MYELODYSPLASTIC SYNDROME",
      "count": 385
    },
    {
      "term": "FATIGUE",
      "count": 373
    },
    {
      "term": "ASTHENIA",
      "count": 332
    },
    {
      "term": "TUMOUR LYSIS SYNDROME",
      "count": 301
    },
    {
      "term": "VOMITING",
      "count": 299
    },
    {
      "term": "RESPIRATORY FAILURE",
      "count": 284
    },
    {
      "term": "ACUTE KIDNEY INJURY",
      "count": 278
    },
    {
      "term": "DYSPNOEA",
      "count": 271
    },
    {
      "term": "HAEMOGLOBIN DECREASED",
      "count": 267
    },
    {
      "term": "COVID-19",
      "count": 259
    },
    {
      "term": "GENERAL PHYSICAL HEALTH DETERIORATION",
      "count": 236
    },
    {
      "term": "CONSTIPATION",
      "count": 227
    },
    {
      "term": "PRODUCT USE IN UNAPPROVED INDICATION",
      "count": 225
    },
    {
      "term": "HYPOTENSION",
      "count": 217
    },
    {
      "term": "MALIGNANT NEOPLASM PROGRESSION",
      "count": 211
    },
    {
      "term": "MULTIPLE ORGAN DYSFUNCTION SYNDROME",
      "count": 197
    },
    {
      "term": "PRODUCT USE ISSUE",
      "count": 191
    },
    {
      "term": "FALL",
      "count": 184
    },
    {
      "term": "BRONCHOPULMONARY ASPERGILLOSIS",
      "count": 183
    },
    {
      "term": "PLEURAL EFFUSION",
      "count": 182
    },
    {
      "term": "PNEUMONITIS",
      "count": 182
    },
    {
      "term": "ATRIAL FIBRILLATION",
      "count": 175
    },
    {
      "term": "BACTERAEMIA",
      "count": 171
    },
    {
      "term": "DECREASED APPETITE",
      "count": 170
    },
    {
      "term": "CARDIAC FAILURE",
      "count": 169
    },
    {
      "term": "LEUKOPENIA",
      "count": 168
    },
    {
      "term": "RASH",
      "count": 166
    },
    {
      "term": "CONDITION AGGRAVATED",
      "count": 165
    },
    {
      "term": "THERAPY NON-RESPONDER",
      "count": 158
    },
    {
      "term": "BONE MARROW FAILURE",
      "count": 157
    },
    {
      "term": "PNEUMONIA FUNGAL",
      "count": 156
    },
    {
      "term": "HAEMATOTOXICITY",
      "count": 155
    },
    {
      "term": "HYPOKALAEMIA",
      "count": 153
    },
    {
      "term": "URINARY TRACT INFECTION",
      "count": 151
    },
    {
      "term": "RENAL FAILURE",
      "count": 147
    },
    {
      "term": "CELLULITIS",
      "count": 146
    },
    {
      "term": "ABDOMINAL PAIN",
      "count": 144
    },
    {
      "term": "OEDEMA PERIPHERAL",
      "count": 144
    },
    {
      "term": "THERAPEUTIC PRODUCT EFFECT INCOMPLETE",
      "count": 144
    },
    {
      "term": "DIZZINESS",
      "count": 142
    },
    {
      "term": "NEUTROPENIC SEPSIS",
      "count": 137
    },
    {
      "term": "COUGH",
      "count": 136
    },
    {
      "term": "GASTROINTESTINAL HAEMORRHAGE",
      "count": 135
    },
    {
      "term": "EPISTAXIS",
      "count": 134
    },
    {
      "term": "MALAISE",
      "count": 134
    },
    {
      "term": "TREATMENT FAILURE",
      "count": 133
    },
    {
      "term": "FULL BLOOD COUNT DECREASED",
      "count": 132
    },
    {
      "term": "AGRANULOCYTOSIS",
      "count": 131
    },
    {
      "term": "TOXICITY TO VARIOUS AGENTS",
      "count": 127
    },
    {
      "term": "SYNCOPE",
      "count": 123
    },
    {
      "term": "LEUKOCYTOSIS",
      "count": 120
    },
    {
      "term": "CEREBRAL HAEMORRHAGE",
      "count": 117
    },
    {
      "term": "DRUG INTERACTION",
      "count": 117
    },
    {
      "term": "COLITIS",
      "count": 110
    },
    {
      "term": "HYPOXIA",
      "count": 110
    },
    {
      "term": "PAIN",
      "count": 109
    },
    {
      "term": "FUNGAL INFECTION",
      "count": 104
    },
    {
      "term": "GRAFT VERSUS HOST DISEASE",
      "count": 104
    },
    {
      "term": "BLOOD CREATININE INCREASED",
      "count": 103
    },
    {
      "term": "DISEASE RECURRENCE",
      "count": 102
    },
    {
      "term": "HAEMORRHAGE",
      "count": 102
    },
    {
      "term": "CARDIAC ARREST",
      "count": 99
    },
    {
      "term": "CONFUSIONAL STATE",
      "count": 99
    },
    {
      "term": "HOSPITALISATION",
      "count": 99
    },
    {
      "term": "PERICARDITIS",
      "count": 99
    },
    {
      "term": "PERICARDIAL EFFUSION",
      "count": 97
    },
    {
      "term": "HEADACHE",
      "count": 96
    },
    {
      "term": "DEEP VEIN THROMBOSIS",
      "count": 95
    },
    {
      "term": "DRUG INEFFECTIVE FOR UNAPPROVED INDICATION",
      "count": 95
    },
    {
      "term": "MUCOSAL INFLAMMATION",
      "count": 95
    },
    {
      "term": "RENAL IMPAIRMENT",
      "count": 95
    },
    {
      "term": "SUBDURAL HAEMATOMA",
      "count": 95
    },
    {
      "term": "ASPERGILLUS INFECTION",
      "count": 94
    },
    {
      "term": "WEIGHT DECREASED",
      "count": 94
    },
    {
      "term": "CHILLS",
      "count": 91
    },
    {
      "term": "BACK PAIN",
      "count": 90
    },
    {
      "term": "C-REACTIVE PROTEIN INCREASED",
      "count": 88
    }
  ]
}